PANTHER Gene Information

Gene Symbol(s):

aroE

Organism:

Escherichia coli

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Gene Name:

Shikimate dehydrogenase (NADP(+))

Gene ID:

BAE78010

Protein ID:

P15770

Persistent Id:

PTN001078618

Alternate Ids:

U00096(EMBL)	991973108(GI)
BAE78010(EMBL-CDS)	AROE_ECOLI(UniProtKB-ID)
BAE78010(Ensembl)	SD {ECO:0000303\|PubMed:3883995}(Synonym)
1.1.1.25 {ECO:0000269\|PubMed:12637497}(EC)	NC_000913(refSeq)
Q2M6U6(AltAccession)	EcoCyc:AROE-MON(BioCyc)
BAE78010(Ensembl_TRS)	aroE{ECO:0000255\|HAMAP-Rule:MF_00222,ECO:0000303\|PubMed:3883995}(Symbol)
BAE78010(Ensembl_PRO)	947776(GeneID)
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PANTHER Classification

PANTHER Family:	SHIKIMATE DEHYDROGENASE (PTHR21089)
PANTHER Subfamily:	BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC (PTHR21089:SF1)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
PANTHER GO-slim Biological Process:	carboxylic acid biosynthetic process monocarboxylic acid metabolic process dicarboxylic acid metabolic process organic hydroxy compound metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	dehydrogenase

Pathway Categories:

Chorismate biosynthesis

Shikimate dehydrogenase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	nucleotide binding, NADP binding, protein binding, oxidoreductase activity, shikimate 3-dehydrogenase (NADP+) activity
GO BP Complete:	aromatic amino acid family biosynthetic process, chorismate biosynthetic process, amino acid biosynthetic process, shikimate metabolic process
GO CC Complete:	cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
EMENI\|EnsemblGenome=ANIA_01137\|UniProtKB=P25415	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G11590\|UniProtKB=Q4WSU5	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU06025\|UniProtKB=P11635	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_09188\|UniProtKB=A7EV30	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_11439\|UniProtKB=Q0U9X5	Phaeosphaeria nodorum	O
ASPFU\|EnsemblGenome=AFUA_3G14790\|UniProtKB=Q4WYZ4	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_3G14800\|UniProtKB=Q4WYZ6	Neosartorya fumigata	O
PHANO\|EnsemblGenome=SNOG_10413\|UniProtKB=Q0UCV1	Phaeosphaeria nodorum	O
ASPFU\|EnsemblGenome=AFUA_3G14830\|UniProtKB=Q4WYZ9	Neosartorya fumigata	O
CHLRE\|EnsemblGenome=CHLRE_08g380201v5\|UniProtKB=A0A2K3DHZ1	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00057p00139480\|UniProtKB=U5D353	Amborella trichopoda	O
AMBTC\|EnsemblGenome=AMTR_s00057p00139000\|UniProtKB=U5D8Z0	Amborella trichopoda	O
AMBTC\|EnsemblGenome=AMTR_s00057p00137940\|UniProtKB=U5D5Z9	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_21G00140\|UniProtKB=A0A0K9PLS3	Zostera marina	O
MUSAM\|EnsemblGenome=Ma07_g03780\|UniProtKB=A0A804JRU2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma07_g03770\|UniProtKB=A0A804JRU1	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma00_g01290\|UniProtKB=A0A804HM87	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_000995mg\|UniProtKB=K3XGH5	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3003G169900\|UniProtKB=C5XLB0	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb131900\|UniProtKB=A0A804N3I3	Zea mays	O
ORYSJ\|EnsemblGenome=Os01g0375200\|UniProtKB=A0A0P0V2T4	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_2g13170v3\|UniProtKB=I1HFE3	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0263100\|UniProtKB=A0A287KXN1	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS3B02G229000\|UniProtKB=A0A077RRZ5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G196700\|UniProtKB=A0A3B6EEU1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G205800\|UniProtKB=A0A3B6GR09	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_021763mg\|UniProtKB=K3Z5E5	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3008G116100\|UniProtKB=A0A1B6PDJ7	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb137730\|UniProtKB=A0A804N5Z6	Zea mays	O
SETIT\|EnsemblGenome=SETIT_021701mg\|UniProtKB=K3Z583	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3008G116000\|UniProtKB=A0A1B6PD58	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb410660\|UniProtKB=B4FAK2	Zea mays	O
BRADI\|EnsemblGenome=BRADI_4g05897v3\|UniProtKB=A0A0Q3EJC2	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0446450\|UniProtKB=F2DVE5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5B02G102400\|UniProtKB=A0A3B6LID5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G096500\|UniProtKB=A0A3B6KD16	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G109200\|UniProtKB=A0A3B6MML5	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_012320\|UniProtKB=A0A1U7YTB9	Nelumbo nucifera	O
NELNU\|Gene=LOC104588429\|UniProtKB=A0A1U7YYL0	Nelumbo nucifera	O
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0386091\|UniProtKB=A0A251TVZ3	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400211510\|UniProtKB=A0A9R1W0G4	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a018925mg\|UniProtKB=A0A022QK40	Erythranthe guttata	O
SOLTU\|EnsemblGenome=PGSC0003DMG400005284\|UniProtKB=M1A2Z6	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc10g038080.2\|UniProtKB=A0A3Q7IET9	Solanum lycopersicum	O
TOBAC\|Gene=LOC107767176\|UniProtKB=A0A1S3XNU3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107777512\|UniProtKB=A0A1S3YM00	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi14g00340\|UniProtKB=D7TUX1	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_B01770\|UniProtKB=A0A059D2L5	Eucalyptus grandis	O
GOSHI\|Gene=LOC107948831\|UniProtKB=A0A1U8NLR6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107895018\|UniProtKB=A0A1U8IC59	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_025937\|UniProtKB=A0A061F7Z5	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g010050mg\|UniProtKB=A0A067DTM3	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_013G029900v3\|UniProtKB=A0A2K1Y068	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_005G043400v3\|UniProtKB=B9MZN1	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_09G160900\|UniProtKB=A0A2C9VDJ1	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1429640\|UniProtKB=B9REX9	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_19G239800\|UniProtKB=I1NC40	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_03G242400\|UniProtKB=K7KGR8	Glycine max	O
JUGRE\|EnsemblGenome=Jr11_01690\|UniProtKB=A0A6P9F9E2	Juglans regia	O
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0178011\|UniProtKB=A0A251V236	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900484080\|UniProtKB=A0A9R1WSD3	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C800411630\|UniProtKB=A0A9R1WZ17	Lactuca sativa	O
CAPAN\|EnsemblGenome=T459_18594\|UniProtKB=A0A1U8H1H5	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG402024041\|UniProtKB=M1C808	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc06g084460.3\|UniProtKB=A0A3Q7H2B2	Solanum lycopersicum	O
TOBAC\|Gene=LOC107832188\|UniProtKB=A0A1S4DPY2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107780015\|UniProtKB=A0A1S3YV46	Nicotiana tabacum	O
EUCGR\|EnsemblGenome=EUGRSUZ_H01214\|UniProtKB=A0A059AXT5	Eucalyptus grandis	O
GOSHI\|Gene=LOC107912389\|UniProtKB=A0A1U8K5W4	Gossypium hirsutum	O
CITSI\|Gene_ORFName=CISIN_1g0101011mg\|UniProtKB=A0A067H5W7	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_014G135500v3\|UniProtKB=A0A2K1XV59	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_05G068500\|UniProtKB=A0A2C9VTX1	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0556770\|UniProtKB=B9S3X5	Ricinus communis	O
JUGRE\|Gene=LOC108992125\|UniProtKB=A0A6P9DT45	Juglans regia	O
SPIOL\|Gene=LOC110790994\|UniProtKB=A0A9R0ILV6	Spinacia oleracea	O
VITVI\|EnsemblGenome=Vitvi14g00338\|UniProtKB=D7TUX3	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_H04428\|UniProtKB=A0A059B665	Eucalyptus grandis	O
GOSHI\|Gene=LOC107936270\|UniProtKB=A0A1U8MC81	Gossypium hirsutum	O
GOSHI\|Gene=LOC107899185\|UniProtKB=A0A1U8IWL5	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_025933\|UniProtKB=A0A061F7Y9	Theobroma cacao	O
THECC\|EnsemblGenome=TCM_028418\|UniProtKB=A0A061GBR9	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_013G029800v3\|UniProtKB=B9I835	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_09G161200\|UniProtKB=A0A2C9VCT3	Manihot esculenta	O
SOYBN\|EnsemblGenome=GLYMA_20G230300\|UniProtKB=K7N563	Glycine max	O
JUGRE\|EnsemblGenome=Jr11_01710\|UniProtKB=A0A2I4GUQ8	Juglans regia	O
PRUPE\|EnsemblGenome=PRUPE_6G334000\|UniProtKB=A0A251NZB1	Prunus persica	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0596901\|UniProtKB=A0A251SU60	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr13g0410851\|UniProtKB=A0A251SUT8	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr13g0596861\|UniProtKB=A0A9K3EJR9	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr03g0122341\|UniProtKB=A0A251V834	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C500247010\|UniProtKB=A0A9R1VMN3	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a004563mg\|UniProtKB=A0A022QM17	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_02922\|UniProtKB=A0A2G3ALF2	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc01g067750.3\|UniProtKB=O65917	Solanum lycopersicum	O
TOBAC\|Gene=LOC107767464\|UniProtKB=A0A1S3XPT5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107791190\|UniProtKB=A0A1S3ZWB9	Nicotiana tabacum	O
TOBAC\|Gene=LOC107793657\|UniProtKB=A0A1S4A4K2	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi14g00339\|UniProtKB=D7TUX2	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_H04427\|UniProtKB=A0A059B7R5	Eucalyptus grandis	O
THECC\|EnsemblGenome=TCM_025936\|UniProtKB=A0A061F132	Theobroma cacao	O
MANES\|EnsemblGenome=MANES_09G161100\|UniProtKB=A0A2C9VCI6	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1429650\|UniProtKB=B9REY0	Ricinus communis	O
JUGRE\|EnsemblGenome=Jr11_01700\|UniProtKB=A0A2I4GUQ1	Juglans regia	O
VITVI\|EnsemblGenome=Vitvi05g00364\|UniProtKB=F6HDI5	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_J00263\|UniProtKB=A0A059AA60	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C03P42120.1\|UniProtKB=A0A078F0U2	Brassica napus	O
BRACM\|EnsemblGenome=Bra001195\|UniProtKB=M4CAG6	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A05P41690.1\|UniProtKB=A0A078GDT9	Brassica napus	O
BRACM\|EnsemblGenome=Bra020756\|UniProtKB=M4DW62	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00006032001\|UniProtKB=A0A078G2G2	Brassica napus	O
BRACM\|EnsemblGenome=Bra040225\|UniProtKB=M4FGJ7	Brassica campestris	O
ARATH\|TAIR=locus=2081036\|UniProtKB=Q9SQT8	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107891874\|UniProtKB=A0A1U8I213	Gossypium hirsutum	O
GOSHI\|Gene=LOC107888918\|UniProtKB=A0A1U8HRQ8	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_021117\|UniProtKB=A0A061ENF3	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g0071512mg\|UniProtKB=A0A067G8P9	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_010G019000v3\|UniProtKB=B9HSF2	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_008G196100v3\|UniProtKB=A0A2K1ZK61	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_010G020600v3\|UniProtKB=A0A2K1YMJ3	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_12G070400\|UniProtKB=A0A2C9UU20	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_2109380\|UniProtKB=B9TKW5	Ricinus communis	O
RICCO\|Gene_ORFName=RCOM_0679510\|UniProtKB=B9RSY7	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_08G264000\|UniProtKB=A0A0R0IYA2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_01G082200\|UniProtKB=A0A0R0LCZ4	Glycine max	O
MEDTR\|EnsemblGenome=MTR_4g090620\|UniProtKB=G7JQT3	Medicago truncatula	O
JUGRE\|Gene=LOC108995064\|UniProtKB=A0A6P9EK95	Juglans regia	O
JUGRE\|EnsemblGenome=Jr12_11820\|UniProtKB=A0A2I4G9N3	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_6G486810\|UniProtKB=A0A0A0KFV4	Cucumis sativus	O
CUCSA\|EnsemblGenome=Csa_2G297240\|UniProtKB=A0A0A0LQ48	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_6G166100\|UniProtKB=A0A251NRG5	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_6G166200\|UniProtKB=M5WAF1	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_269650\|UniProtKB=D8T411	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_233322\|UniProtKB=D8S7P3	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c3_23920\|UniProtKB=A0A7I4FMC2	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0047s0090\|UniProtKB=A0A2R6WZ31	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_002570140\|UniProtKB=A0A1Y1IAX7	Klebsormidium nitens	O
NITMS\|EnsemblGenome=Nmar_0550\|UniProtKB=A9A233	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_1090\|UniProtKB=B1L5V7	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0306\|UniProtKB=Q980I8	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE1913\|UniProtKB=Q8ZW89	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_4594\|UniProtKB=Q8THC3	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_1084\|UniProtKB=Q58484	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_0382G\|UniProtKB=Q9HS68	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0265\|UniProtKB=Q5JFT1	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_1944\|UniProtKB=A9WE00	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO1498\|UniProtKB=Q9KXQ2	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv2552c\|UniProtKB=I6Y120	Mycobacterium tuberculosis	O
CLOBH\|Gene_OrderedLocusName=CBO2540\|UniProtKB=A5I4X1	Clostridium botulinum	O
STAA8\|EnsemblGenome=SAOUHSC_01699\|UniProtKB=Q2FXY1	Staphylococcus aureus	O
LISMO\|Gene=aroE\|UniProtKB=Q8Y733	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_25660\|UniProtKB=P54374	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4331\|UniProtKB=Q818D0	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_0346\|UniProtKB=Q9WYI1	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_1173\|UniProtKB=Q9RV57	Deinococcus radiodurans	O
GLOVI\|Gene=aroE\|UniProtKB=Q7NG95	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA18699\|UniProtKB=P74591	Synechocystis	O
LEPIN\|EnsemblGenome=LA_0638\|UniProtKB=Q8F8C0	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_4215\|UniProtKB=Q8A006	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB6488\|UniProtKB=Q7UQ72	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_901\|UniProtKB=O67049	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A0423\|UniProtKB=B5YJ55	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_1054\|UniProtKB=B8E257	Dictyoglomus turgidum	O
FUSNN\|EnsemblGenome=FN0045\|UniProtKB=Q8RH65	Fusobacterium nucleatum	O
NEIMB\|EnsemblGenome=NMB0358\|UniProtKB=P56992	Neisseria meningitidis serogroup b	LDO
COXBU\|EnsemblGenome=CBU_0010\|UniProtKB=Q83FD0	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_0655\|UniProtKB=P43876	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_0040\|UniProtKB=Q8EKQ0	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_0056\|UniProtKB=Q9KVT3	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC3953\|UniProtKB=Q8P3W6	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA0025\|UniProtKB=P43904	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM3401\|UniProtKB=Q8ZLN1	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_0245\|UniProtKB=Q8ZJ74	Yersinia pestis	LDO