PANTHER Gene Information   
Gene Symbol(s): Hsd11b1
Organism: Rattus norvegicus
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Gene Name: 11-beta-hydroxysteroid dehydrogenase 1
Gene ID: 2834
Protein ID: P16232
Persistent Id: PTN000674102
Alternate Ids:
1.1.1.146 {ECO:0000269|PubMed:12460758, ECO:0000269|PubMed:14973125, ECO:0000269|PubMed:2808402, ECO:0000269|PubMed:8613810}(EC) 23830928(GI)
Q6LDH6(AltAccession) Hsd11b1{ECO:0000312|RGD:2834}(Symbol)
BC078865(EMBL) 25116(GeneID)
2834(RGD) Hsd11(Synonym)
CHEMBL2391(ChEMBL) DHI1_RAT(UniProtKB-ID)
AAH78865(EMBL-CDS)
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PANTHER Classification
PANTHER Family: HYDROXYSTEROID (11-BETA) DEHYDROGENASE 1-LIKE B-RELATED (PTHR44279)
PANTHER Subfamily: 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 (PTHR44279:SF1)  
PANTHER GO-slim Molecular Function: steroid binding
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
PANTHER GO-slim Biological Process: steroid catabolic process
PANTHER GO-slim Cellular Component: endoplasmic reticulum membrane
PANTHER protein class: dehydrogenase
Pathway Categories: No pathway information available
GO MF Complete: 7-beta-hydroxysteroid dehydrogenase (NADP+) activity, NADP binding, protein homodimerization activity, oxidoreductase activity, steroid binding, 11-beta-hydroxysteroid dehydrogenase (NADP+) activity
GO BP Complete: glucocorticoid biosynthetic process, cellular response to estradiol stimulus, glucocorticoid catabolic process, steroid catabolic process, mineralocorticoid metabolic process, response to nutrient levels, regulation of pentose-phosphate shunt, lung development
GO CC Complete: endoplasmic reticulum membrane, nuclear membrane, apical part of cell, intracellular membrane-bounded organelle
Reactome Pathways: Metabolism, Prednisone ADME, Glucocorticoid biosynthesis, Metabolism of lipids, Drug ADME, Metabolism of steroids, Metabolism of steroid hormones