PANTHER Gene Information   
Gene Symbol(s): Ascl1
Organism: Rattus norvegicus
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Gene Name: Achaete-scute homolog 1
Gene ID: 71010
Protein ID: P19359
Persistent Id: PTN000358380
Alternate Ids:
64186(GeneID) NP_071779(refSeq)
Ascl1(Symbol) Mash-1(Synonym)
CAA37760(EMBL-CDS) 71010(RGD)
114254(GI) ASCL1_RAT(UniProtKB-ID)
X53725(EMBL) ENSRNOG00000004294(Ensembl)
ENSRNOP00000005674(Ensembl_PRO) ENSRNOT00000005674(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED (PTHR13935)
PANTHER Subfamily: ACHAETE-SCUTE HOMOLOG 1 (PTHR13935:SF66)  
PANTHER GO-slim Molecular Function: DNA-binding transcription factor activity, RNA polymerase II-specific
RNA polymerase II transcription regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process: positive regulation of transcription by RNA polymerase II
neuron differentiation
regulation of neurogenesis
sensory organ development
PANTHER GO-slim Cellular Component: RNA polymerase II transcription regulator complex
PANTHER protein class: basic helix-loop-helix transcription factor
Pathway Categories: Gonadotropin-releasing hormone receptor pathway
   MASH1
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: identical protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, double-stranded DNA binding, sequence-specific DNA binding, protein dimerization activity, DNA-binding transcription repressor activity, RNA polymerase II-specific, chromatin binding, DNA-binding transcription factor activity, RNA polymerase II-specific, bHLH transcription factor binding, nucleic acid binding, DNA-binding transcription factor activity, sequence-specific double-stranded DNA binding, E-box binding
GO BP Complete: regulation of timing of subpallium neuron differentiation, response to epidermal growth factor, olfactory pit development, forebrain neuron differentiation, subpallium neuron fate commitment, neurogenesis, central nervous system neuron development, vestibular nucleus development, neuroblast proliferation, response to retinoic acid, negative regulation of DNA-templated transcription, cellular response to magnetism, neuron differentiation, regulation of Notch signaling pathway, commitment of neuronal cell to specific neuron type in forebrain, pattern specification process, cerebral cortex development, regulation of mitotic cell cycle, sensory organ development, musculoskeletal movement, spinal reflex action, Notch signaling pathway, regulation of epithelial cell differentiation, regulation of gene expression, positive regulation of neurogenesis, regulation of neurogenesis, oligodendrocyte development, oligodendrocyte cell fate commitment, neural precursor cell proliferation, nervous system development, negative regulation of neuron differentiation, positive regulation of neuron differentiation, positive regulation of cell cycle, generation of neurons, cerebral cortex GABAergic interneuron differentiation, positive regulation of transcription by RNA polymerase II, spinal cord oligodendrocyte cell fate specification, positive regulation of Notch signaling pathway, positive regulation of neuron apoptotic process, peripheral nervous system neuron development, negative regulation of transcription by RNA polymerase II, heart development, neuron fate specification, neuron fate commitment, positive regulation of neural precursor cell proliferation, lung neuroendocrine cell differentiation, oligodendrocyte differentiation, neuroendocrine cell differentiation, stomach neuroendocrine cell differentiation, carotid body glomus cell differentiation, spinal cord association neuron differentiation, spinal cord oligodendrocyte cell differentiation, neuroblast fate determination, sympathetic ganglion development, cell maturation, neuron development, adrenal chromaffin cell differentiation, regulation of cell population proliferation, regulation of transcription by RNA polymerase II, ventral spinal cord interneuron fate commitment, noradrenergic neuron development, GABAergic neuron differentiation, noradrenergic neuron fate commitment, motor neuron migration, negative regulation of apoptotic process, response to folic acid
GO CC Complete: nucleus, RNA polymerase II transcription regulator complex, neuronal cell body, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs