PANTHER Gene Information   
Gene Symbol(s): Tdo2
Organism: Rattus norvegicus
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Gene Name: Tryptophan 2,3-dioxygenase
Gene ID: 68370
Protein ID: P21643
Persistent Id: PTN000015606
Alternate Ids:
T23O_RAT(UniProtKB-ID) TO {ECO:0000255|HAMAP-Rule:MF_03020}(Synonym)
NM_022403(refSeq) Q6LBW3(AltAccession)
56811(GI) 1.13.11.11 {ECO:0000255|HAMAP-Rule:MF_03020}(EC)
CAA25974(EMBL-CDS) ENSRNOG00000011612(Ensembl)
ENSRNOT00000015732(Ensembl_TRS) X01849(EMBL)
64206(GeneID) Tdo2{ECO:0000255|HAMAP-Rule:MF_03020}(Symbol)
68370(RGD) ENSRNOP00000015732(Ensembl_PRO)
CHEMBL2686(ChEMBL)
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PANTHER Classification
PANTHER Family: TRYPTOPHAN 2,3-DIOXYGENASE (PTHR10138)
PANTHER Subfamily: TRYPTOPHAN 2,3-DIOXYGENASE (PTHR10138:SF0)  
PANTHER GO-slim Molecular Function: heme binding
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
PANTHER GO-slim Biological Process: cellular nitrogen compound catabolic process
aromatic amino acid family catabolic process
biogenic amine metabolic process
acyl-CoA metabolic process
alpha-amino acid metabolic process
amino acid catabolic process
heterocycle catabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class: oxygenase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: oxygen binding, identical protein binding, tryptophan 2,3-dioxygenase activity, metal ion binding, amino acid binding, heme binding
GO BP Complete: protein homotetramerization, tryptophan catabolic process to kynurenine, tryptophan catabolic process to acetyl-CoA, response to nitroglycerin, tryptophan metabolic process
GO CC Complete: -
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Metabolism, Tryptophan catabolism, Metabolism of amino acids and derivatives

Orthologs