PANTHER Gene Information

Gene Symbol(s):

CHA1

Organism:

Saccharomyces cerevisiae

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Gene Name:

Catabolic L-serine_threonine dehydratase

Gene ID:

S000000569

Protein ID:

P25379

Persistent Id:

PTN000034627

Alternate Ids:

STDH_YEAST(UniProtKB-ID)	NM_001178706(refSeq)
D6VQV4(AltAccession)	63535562(GI)
4.3.1.19(EC)	YEAST:YCL064C-MON(BioCyc)
M85194(EMBL)	S000000569(SGD)
CHA1(Symbol)	YCL064C_mRNA(Ensembl_TRS)
AAA35040(EMBL-CDS)	L-threonine deaminase(Synonym)
YCL064C(Ensembl_PRO)	YCL064C(Ensembl)
850295(GeneID)
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PANTHER Classification

PANTHER Family:	THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED (PTHR48078)
PANTHER Subfamily:	CATABOLIC L-SERINE_THREONINE DEHYDRATASE (PTHR48078:SF2)
PANTHER GO-slim Molecular Function:	lyase activity
PANTHER GO-slim Biological Process:	branched-chain amino acid biosynthetic process aspartate family amino acid metabolic process amino acid catabolic process alpha-amino acid biosynthetic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	dehydratase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	L-serine ammonia-lyase activity, pyridoxal phosphate binding, lyase activity, threonine deaminase activity
GO BP Complete:	amino acid metabolic process, threonine catabolic process, L-serine catabolic process
GO CC Complete:	mitochondrion, mitochondrial nucleoid

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism, Metabolism of amino acids and derivatives, Threonine catabolism

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10691\|UniProtKB=P20132	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000005491.3\|UniProtKB=H2Q6Y1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000007318.3\|UniProtKB=G3QWK1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000004208.4\|UniProtKB=F6Z3Z0	Macaca mulatta	O
MOUSE\|MGI=MGI=98270\|UniProtKB=Q8VBT2	Mus musculus	O
RAT\|RGD=67376\|UniProtKB=P09367	Rattus norvegicus	O
BOVIN\|Gene=SDS\|UniProtKB=Q0VCW4	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000031814.3\|UniProtKB=F1N0R8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00005034755.1\|UniProtKB=K9IVJ5	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000024950.4\|UniProtKB=A0A9L0R5E7	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000032375.3\|UniProtKB=A0A2I2US35	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845024052.1\|UniProtKB=A0A8I3PVD9	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000003535.4\|UniProtKB=F7GBQ6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000044882.1\|UniProtKB=A0A6I8PFD4	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000042061.1\|UniProtKB=A0A803T9H3	Anolis carolinensis	O
XENLA\|Gene=sds.S\|UniProtKB=A1L2R8	Xenopus laevis	O
XENLA\|Gene=sds.L\|UniProtKB=A1L2T1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-921978\|UniProtKB=F7BVD4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000023397.1\|UniProtKB=A0A3B3HKT1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029865.1\|UniProtKB=A0A3B3HDD3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000026663.1\|UniProtKB=A0A3B3IPC2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000024632.1\|UniProtKB=A0A3B3IKV0	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000007734.1\|UniProtKB=W5MLY1	lepisosteus oculatus	O
HUMAN\|HGNC=30404\|UniProtKB=Q96GA7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000005492.5\|UniProtKB=H2Q6Y2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010575.3\|UniProtKB=G3R4U7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000020665.4\|UniProtKB=F7BEL5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2182607\|UniProtKB=Q8R238	Mus musculus	LDO
RAT\|RGD=1309192\|UniProtKB=D3ZHV7	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000008945.5\|UniProtKB=A5PKH5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005034510.1\|UniProtKB=A0A4X1TIZ3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022258.4\|UniProtKB=A0A3Q2LE78	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005084.6\|UniProtKB=M3W3F5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845024122.1\|UniProtKB=A0A8I3PH52	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000003565.4\|UniProtKB=F7G139	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000037171.1\|UniProtKB=A0A6I8P497	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010000447.1\|UniProtKB=A0A8V0X067	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000005037.4\|UniProtKB=H9G9U1	Anolis carolinensis	LDO
XENLA\|Gene=sdsl.S\|UniProtKB=Q6PAE9	Xenopus laevis	LDO
XENLA\|Gene=LOC121399475\|UniProtKB=A0A8J1M3A8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-922203\|UniProtKB=A0A6I8Q911	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000026856.1\|UniProtKB=A0A3B3HZL1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-131121-410\|UniProtKB=A0A8M9PEB6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007758.1\|UniProtKB=W5MM16	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000022604.1\|UniProtKB=H2XNN8	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118425400\|UniProtKB=A0A9J7LWP2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC594261\|UniProtKB=A0A7M7P9A3	Strongylocentrotus purpuratus	LDO
HELRO\|EnsemblGenome=HelroG105471\|UniProtKB=T1EDV2	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g241178\|UniProtKB=A7RWI2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG28057\|UniProtKB=B3S1X5	Trichoplax adhaerens	LDO
EREGS\|EnsemblGenome=AGOS_AFR747W\|UniProtKB=Q751S7	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000177673\|UniProtKB=A0A1D8PGA8	Candida albicans	LDO
CANAL\|CGD=CAL0000177340\|UniProtKB=A0A1D8PKG0	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B16214g\|UniProtKB=Q6CEE8	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_E10307g\|UniProtKB=Q6C6D8	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_03866\|UniProtKB=Q5B6G4	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G07810\|UniProtKB=Q4WP28	Neosartorya fumigata	O
EMENI\|EnsemblGenome=ANIA_04217\|UniProtKB=C8V4B5	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G06150\|UniProtKB=Q4WJF6	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03761\|UniProtKB=Q1K7B4	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_06079\|UniProtKB=A7EL82	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03797\|UniProtKB=Q0UWR7	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_09456\|UniProtKB=Q0UFK8	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNK00180\|UniProtKB=Q5K9Z3	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNE02390\|UniProtKB=Q5KGT7	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_01692\|UniProtKB=A0A0D1E4A6	Ustilago maydis	LDO
DICDI\|dictyBase=DDB_G0272787\|UniProtKB=Q86B06	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_98285\|UniProtKB=F0ZP75	Dictyostelium purpureum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_262207\|UniProtKB=B8BZN7	Thalassiosira pseudonana	LDO
NITMS\|EnsemblGenome=Nmar_1549\|UniProtKB=A9A4Z1	Nitrosopumilus maritimus	O
NITMS\|EnsemblGenome=Nmar_0848\|UniProtKB=A9A5N3	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_0521\|UniProtKB=B1L495	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0248\|UniProtKB=Q980P1	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE2316\|UniProtKB=Q8ZVF0	Pyrobaculum aerophilum	O
HALSA\|EnsemblGenome=VNG_2100G\|UniProtKB=Q9HNH6	Halobacterium salinarum	O
BACSU\|EnsemblGenome=BSU_23770\|UniProtKB=P54555	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_1725\|UniProtKB=Q81F73	Bacillus cereus	O
FUSNN\|EnsemblGenome=FN0553\|UniProtKB=Q8RFX6	Fusobacterium nucleatum	O
VIBCH\|EnsemblGenome=VC_A0875\|UniProtKB=Q9KL72	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA3357\|UniProtKB=Q9HYN9	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM3802\|UniProtKB=Q8ZL08	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAA16229\|UniProtKB=P00926	Escherichia coli	O
CHLAA\|EnsemblGenome=Caur_1249\|UniProtKB=A9WK26	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_3892\|UniProtKB=A9WDF0	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO7292\|UniProtKB=Q9K4M2	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4962\|UniProtKB=Q9EWG3	Streptomyces coelicolor	O
CLOBH\|Gene_OrderedLocusName=CBO3502\|UniProtKB=A5I7M9	Clostridium botulinum	O
THEMA\|EnsemblGenome=TM_0356\|UniProtKB=Q9WYJ1	Thermotoga maritima	O
DICTD\|EnsemblGenome=Dtur_1494\|UniProtKB=B8E131	Dictyoglomus turgidum	O
FUSNN\|EnsemblGenome=FN1411\|UniProtKB=Q8RDT9	Fusobacterium nucleatum	O
BRADU\|Gene=Q89G45_BRADU\|UniProtKB=Q89G45	Bradyrhizobium diazoefficiens	O
PSEAE\|EnsemblGenome=PA0851\|UniProtKB=Q9I590	Pseudomonas aeruginosa	O
GEOSL\|EnsemblGenome=GSU0486\|UniProtKB=Q74FW6	Geobacter sulfurreducens	O
BRADU\|Gene=Q89UK3_BRADU\|UniProtKB=Q89UK3	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89L17_BRADU\|UniProtKB=Q89L17	Bradyrhizobium diazoefficiens	O
XANCP\|EnsemblGenome=XCC3326\|UniProtKB=Q8P5L2	Xanthomonas campestris	O
SALTY\|EnsemblGenome=STM3244\|UniProtKB=P11954	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAE77166\|UniProtKB=P0AGF6	Escherichia coli	O