PANTHER Gene Information   
Gene Symbol(s): CTSL
Organism: Bos taurus
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Gene Name: Procathepsin L
Gene ID: ENSBTAG00000017077
Protein ID: P25975
Persistent Id: PTN000275088
Alternate Ids:
BC102312(EMBL) BAA33398(EMBL-CDS)
CATL1_BOVIN(UniProtKB-ID) O77502(AltAccession)
ENSBTAT00000022710(Ensembl_TRS) NP_776457(refSeq)
1542853(GI) 3.4.22.15 {ECO:0000250|UniProtKB:P07711}(EC)
CTSL(Symbol) ENSBTAG00000017077(Ensembl)
CHEMBL2113(ChEMBL) CATL1(Synonym)
281108(GeneID) ENSBTAP00000022710(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: CYSTEINE PROTEASE FAMILY C1-RELATED (PTHR12411)
PANTHER Subfamily: CATHEPSIN L2 (PTHR12411:SF57)  
PANTHER GO-slim Molecular Function: cysteine-type endopeptidase activity
PANTHER GO-slim Biological Process: proteolysis involved in protein catabolic process
PANTHER GO-slim Cellular Component: extracellular space
lysosome
PANTHER protein class: cysteine protease
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: collagen binding, proteoglycan binding, histone binding, metal ion binding, serpin family protein binding, fibronectin binding, endopeptidase activity, cysteine-type endopeptidase activity
GO BP Complete: fusion of virus membrane with host endosome membrane, enkephalin processing, adaptive immune response, cellular response to thyroid hormone stimulus, zymogen activation, receptor-mediated endocytosis of virus by host cell, elastin catabolic process, fusion of virus membrane with host plasma membrane, apoptotic process, CD4-positive, alpha-beta T cell lineage commitment, antigen processing and presentation of peptide antigen, protein autoprocessing, collagen catabolic process, proteolysis involved in protein catabolic process
GO CC Complete: extracellular space, chromaffin granule, Golgi apparatus, multivesicular body, plasma membrane, apical plasma membrane, lysosome
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Trafficking and processing of endosomal TLR, Adaptive Immune System, Generic Transcription Pathway, Gene expression (Transcription), MHC class II antigen presentation, Immune System, RNA Polymerase II Transcription, Activation of Matrix Metalloproteinases, Innate Immune System, Toll-like Receptor Cascades, RUNX1 regulates transcription of genes involved in differentiation of keratinocytes, Transcriptional regulation by RUNX1, Extracellular matrix organization, Degradation of the extracellular matrix

Orthologs