PANTHER Gene Information

Gene Symbol(s):

snt-1

Organism:

Caenorhabditis elegans

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Gene Name:

Synaptotagmin-1

Gene ID:

WBGene00004921

Protein ID:

P34693

Persistent Id:

PTN000001961

Alternate Ids:

CCD62852(EMBL-CDS)	289718(GI)
Synaptotagmin I(Synonym)	snt-1(Symbol)
WBGene00004921(WormBase)	174120(GeneID)
F31E8.2a(Ensembl_TRS)	CE02711(WormBase_PRO)
NP_001022129(refSeq)	F31E8.2a(WormBase_TRS)
L15302(EMBL)	WBGene00004921(Ensembl)
SYT1_CAEEL(UniProtKB-ID)	F31E8.2a(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	SYNAPTOTAGMIN (PTHR10024)
PANTHER Subfamily:	SYNAPTOTAGMIN 1 (PTHR10024:SF227)
PANTHER GO-slim Molecular Function:	SNARE binding calcium ion binding phosphatidylserine binding clathrin binding
PANTHER GO-slim Biological Process:	synaptic vesicle exocytosis synaptic vesicle endocytosis calcium-ion regulated exocytosis
PANTHER GO-slim Cellular Component:	plasma membrane exocytic vesicle
PANTHER protein class:	membrane trafficking regulatory protein

Pathway Categories:

Synaptic vesicle trafficking

Synaptotagmin

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metal ion binding, calcium ion binding, calcium ion sensor activity, SNARE binding, calcium-dependent phospholipid binding
GO BP Complete:	regulation of neurotransmitter secretion, regulation of nematode pharyngeal pumping, locomotory behavior, vesicle-mediated transport, synaptic vesicle endocytosis, necroptotic process, calcium-dependent activation of synaptic vesicle fusion, regulation of synaptic vesicle exocytosis, synaptic vesicle exocytosis, regulation of calcium ion-dependent exocytosis, programmed cell death, defecation
GO CC Complete:	exocytic vesicle, synaptic vesicle, membrane, cytoplasmic vesicle, synaptic vesicle membrane, dense core granule, synapse, plasma membrane, axon

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Neurotransmitter release cycle, Norepinephrine Neurotransmitter Release Cycle, GABA synthesis, release, reuptake and degradation, Vesicle-mediated transport, Membrane Trafficking, Serotonin Neurotransmitter Release Cycle, Glutamate Neurotransmitter Release Cycle, Clathrin-mediated endocytosis, Cargo recognition for clathrin-mediated endocytosis, Dopamine Neurotransmitter Release Cycle, Acetylcholine Neurotransmitter Release Cycle, Neuronal System, Transmission across Chemical Synapses

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11513\|UniProtKB=O00445	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000011491.5\|UniProtKB=A0A2J8IWZ5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000009037.3\|UniProtKB=G3R0Z1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000007653.4\|UniProtKB=F7AI08	Macaca mulatta	O
MOUSE\|MGI=MGI=1926368\|UniProtKB=Q9R0N5	Mus musculus	O
RAT\|RGD=3806\|UniProtKB=P47861	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000002522.5\|UniProtKB=A4IFJ2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000021843.4\|UniProtKB=A0A480Y3T9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000003943.4\|UniProtKB=A0A5F5PF67	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005629.5\|UniProtKB=M3W4F2	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845001583.1\|UniProtKB=A0A8I3ME41	Canis lupus familiaris	O
ANOCA\|Ensembl=ENSACAG00000017137.4\|UniProtKB=A0A803T5S5	Anolis carolinensis	O
XENLA\|Gene=syt5.S\|UniProtKB=A0A8J1LD46	Xenopus laevis	O
XENLA\|Gene=syt5.L\|UniProtKB=A0A8J1L9W1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-991349\|UniProtKB=A0A6I8R0H6	Xenopus tropicalis	O
HUMAN\|HGNC=11509\|UniProtKB=P21579	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000024064.5\|UniProtKB=H2R3R2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000024224.2\|UniProtKB=G3S3Z1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005530.4\|UniProtKB=F7GFB1	Macaca mulatta	LDO
MOUSE\|MGI=MGI=99667\|UniProtKB=P46096	Mus musculus	LDO
RAT\|RGD=3803\|UniProtKB=P21707	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000034693\|UniProtKB=P48018	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000948.5\|UniProtKB=F1RYK1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000012832.4\|UniProtKB=F6R134	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000024865.4\|UniProtKB=A0A337STW9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845007651.1\|UniProtKB=A0A8I3N2E5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000020467.5\|UniProtKB=F7FJ84	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007531.4\|UniProtKB=A0A6I8PE80	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012026\|UniProtKB=P47191	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013826.3\|UniProtKB=G1KPD2	Anolis carolinensis	LDO
XENLA\|Gene=LOC108713136\|UniProtKB=A0A1L8GUB6	Xenopus laevis	O
XENLA\|Gene=LOC108711107\|UniProtKB=A0A1L8GYR8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5752629\|UniProtKB=A0A803JC88	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008768.2\|UniProtKB=H2LY02	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000016339.2\|UniProtKB=A0A3B3H997	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040718-165\|UniProtKB=Q5TZ27	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016283.1\|UniProtKB=W5NHI2	lepisosteus oculatus	LDO
CHICK\|Ensembl=ENSGALG00010025620.1\|UniProtKB=A0A8V1AB59	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000028750.2\|UniProtKB=R4GBF2	Anolis carolinensis	O
XENLA\|Gene=LOC108713892\|UniProtKB=A0A1L8GJL0	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000006049\|UniProtKB=F7DU57	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000027185.1\|UniProtKB=A0A3B3IFE2	Oryzias latipes	O
DANRE\|Ensembl=ENSDARG00000107077.2\|UniProtKB=A0A2R8QQP8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002698.1\|UniProtKB=W5M464	lepisosteus oculatus	O
HUMAN\|HGNC=11510\|UniProtKB=Q8N9I0	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001854.5\|UniProtKB=A0A2J8QWL9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000004495.3\|UniProtKB=G3QPB7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000004001.4\|UniProtKB=F6XQZ0	Macaca mulatta	O
MOUSE\|MGI=MGI=99666\|UniProtKB=P46097	Mus musculus	O
RAT\|RGD=3804\|UniProtKB=P29101	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000047648.2\|UniProtKB=A0A3Q1LZP6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000010926.5\|UniProtKB=F1S5A0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000010960.4\|UniProtKB=A0A9L0SH25	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000000454.5\|UniProtKB=A0A337S2H8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845015072.1\|UniProtKB=A0A8I3P087	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000000684.4\|UniProtKB=F6WM83	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000040777.1\|UniProtKB=A0A6I8NT59	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010026315.1\|UniProtKB=A0A8V1A869	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000003847.4\|UniProtKB=G1KCC0	Anolis carolinensis	O
XENLA\|Gene=LOC108709437\|UniProtKB=A0A1L8H6M9	Xenopus laevis	O
XENLA\|Gene=LOC108708151\|UniProtKB=A0A1L8HET0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-981211\|UniProtKB=F7EGU7	Xenopus tropicalis	O
XENTR\|Gene=LOC100493529\|UniProtKB=A0A8J0R089	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000013338.2\|UniProtKB=H2MDR8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060503-315\|UniProtKB=F1R5C0	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000007159.2\|UniProtKB=A0A3B3H431	Oryzias latipes	O
DANRE\|Gene=LOC559637\|UniProtKB=A0A8M9QBF7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009878.1\|UniProtKB=W5MUL7	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000006816.3\|UniProtKB=F6TZR8	Ciona intestinalis	LDO
HUMAN\|HGNC=14962\|UniProtKB=Q7L8C5	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000003534.4\|UniProtKB=H2Q3G7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000017096.3\|UniProtKB=G3S633	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000011449.4\|UniProtKB=G7NDI3	Macaca mulatta	O
MOUSE\|MGI=MGI=1933945\|UniProtKB=Q9EQT6	Mus musculus	O
RAT\|RGD=621877\|UniProtKB=Q925B5	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000001703.5\|UniProtKB=A5D7D7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000031590.3\|UniProtKB=A0A287AVR7	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000023889.4\|UniProtKB=F6XJK4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000030929.4\|UniProtKB=M3XEY5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845029683.1\|UniProtKB=A0A8I3S795	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000019875.4\|UniProtKB=F6WL38	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000039954.1\|UniProtKB=A0A6I8P6V5	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021743.1\|UniProtKB=A0A8V0ZM10	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000014581.4\|UniProtKB=G1KQ23	Anolis carolinensis	O
XENLA\|Gene=LOC108713749\|UniProtKB=A0A1L8GIK8	Xenopus laevis	O
XENLA\|Gene=LOC108715267\|UniProtKB=A0A8J1KHT0	Xenopus laevis	O
XENTR\|Gene=syt13\|UniProtKB=A0A8J1JH03	Xenopus tropicalis	O
DANRE\|Gene=syt13\|UniProtKB=A0A8M6Z749	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000005889.1\|UniProtKB=W5MFF6	lepisosteus oculatus	O
HUMAN\|HGNC=19264\|UniProtKB=Q8NBV8	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000003160.7\|UniProtKB=H2R5N4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000008429.3\|UniProtKB=G3QZC5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000004837.4\|UniProtKB=F7AUE6	Macaca mulatta	O
MOUSE\|MGI=MGI=1859867\|UniProtKB=Q9R0N6	Mus musculus	O
RAT\|RGD=68399\|UniProtKB=Q925B4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000040103.3\|UniProtKB=F1MRS2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000023537.4\|UniProtKB=I3LBJ6	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000025962.4\|UniProtKB=M3X6S3	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845010168.1\|UniProtKB=A0A8I3N970	Canis lupus familiaris	O
CHICK\|Ensembl=ENSGALG00010024615.1\|UniProtKB=A0A8V1A2U0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000009464.4\|UniProtKB=G1KIZ9	Anolis carolinensis	O
XENLA\|Gene=syt1.L\|UniProtKB=Q66KE5	Xenopus laevis	O
XENLA\|Gene=LOC108715204\|UniProtKB=A0A1L8GD54	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-978920\|UniProtKB=F6YG36	Xenopus tropicalis	O
DANRE\|Gene=LOC103909874\|UniProtKB=A0A8M9PND4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002263.1\|UniProtKB=W5M2P4	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000016779.2\|UniProtKB=H2MQH0	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040718-110\|UniProtKB=A7MCG9	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000006860.2\|UniProtKB=H2LRC4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050522-134\|UniProtKB=F1QCC9	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-060503-166\|UniProtKB=A3KQ92	Danio rerio	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_120531\|UniProtKB=C3Z4L9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417681\|UniProtKB=A0A9J7LAS0	Branchiostoma floridae	LDO
BRAFL\|Gene=LOC118406658\|UniProtKB=A0A9J7KK38	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC752447\|UniProtKB=A0A7M7NZL4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC755798\|UniProtKB=A0A7M7G0T7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115917880\|UniProtKB=A0A7M7NYG5	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC115921646\|UniProtKB=A0A7M7NGD2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC373478\|UniProtKB=A0A7M7NYD5	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00032329\|UniProtKB=A8XCL2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00097802\|UniProtKB=A0A2A6BZB9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0261089\|UniProtKB=C0HDP4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008650\|UniProtKB=A0A1S4GYU8	Anopheles gambiae	O
DROME\|FlyBase=FBgn0004242\|UniProtKB=P21521	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007942\|UniProtKB=Q7PN22	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC007227\|UniProtKB=D2A0P6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_442623\|UniProtKB=E9FTC0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011463\|UniProtKB=B7Q6I0	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG170390\|UniProtKB=T1F2Z9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG65797\|UniProtKB=T1FYC7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG163371\|UniProtKB=T1ETY8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG78642\|UniProtKB=T1G3E0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82086\|UniProtKB=T1G4M6	helobdella robusta	LDO
HELRO\|EnsemblGenome=HelroG85838\|UniProtKB=T1G633	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247877\|UniProtKB=A7SX18	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g85661\|UniProtKB=A7RKX9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g136167\|UniProtKB=A7SX19	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g115870\|UniProtKB=A7SEZ4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g136571\|UniProtKB=A7SXC9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g130783\|UniProtKB=A7ST77	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g136185\|UniProtKB=A7SX17	Nematostella vectensis	LDO
TRIAD\|Gene_ORFName=TRIADDRAFT_61791\|UniProtKB=B3SBZ4	Trichoplax adhaerens	LDO