PANTHER Gene Information

Gene Symbol(s):

DUN1

Organism:

Saccharomyces cerevisiae

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Gene Name:

DNA damage response protein kinase DUN1

Gene ID:

S000002259

Protein ID:

P39009

Persistent Id:

PTN002389433

Alternate Ids:

NP_010182(refSeq)	YEAST:G3O-29504-MON(BioCyc)
DUN1_YEAST(UniProtKB-ID)	D6VRP9(AltAccession)
YDL101C(Ensembl_PRO)	AAA16324(EMBL-CDS)
DUN1(Symbol)	851457(GeneID)
DUN1(Synonym)	YDL101C_mRNA(Ensembl_TRS)
6320102(GI)	YDL101C(Ensembl)
2.7.11.1(EC)	S000002259(SGD)
Z74149(EMBL)
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PANTHER Classification

PANTHER Family:	OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED (PTHR44167)
PANTHER Subfamily:	PHOSPHORYLASE KINASE (PTHR44167:SF30)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	mitotic DNA damage checkpoint signaling
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway

Phosphorylase b kinase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP binding, protein kinase activity, protein serine/threonine kinase activity, protein serine kinase activity
GO BP Complete:	DNA damage checkpoint signaling, mitotic DNA damage checkpoint signaling, replication fork processing, double-strand break repair via nonhomologous end joining, DNA damage response
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex, G2/M Checkpoints, DNA Repair, DNA Double-Strand Break Repair, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks, Cell Cycle Checkpoints, p53-Independent DNA Damage Response, DNA Double Strand Break Response, G2/M DNA damage checkpoint, G1/S DNA Damage Checkpoints, Ubiquitin Mediated Degradation of Phosphorylated Cdc25A, p53-Independent G1/S DNA damage checkpoint, Cell Cycle

Orthologs

ID	Organism	Type
HUMAN\|HGNC=14568\|UniProtKB=Q9BYT3	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000003331.6\|UniProtKB=A0A2J8P623	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000041698.1\|UniProtKB=A0A2I2ZSF5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000018471.4\|UniProtKB=F6Y578	Macaca mulatta	O
MOUSE\|MGI=MGI=2152419\|UniProtKB=Q924X7	Mus musculus	O
RAT\|RGD=1590972\|UniProtKB=D4A165	Rattus norvegicus	O
BOVIN\|Gene=STK33\|UniProtKB=Q0VD22	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000011910.5\|UniProtKB=A0A452DJB6	Bos taurus	O
FELCA\|Ensembl=ENSFCAG00000008403.6\|UniProtKB=A0A2I2UA11	Felis catus	O
MONDO\|Ensembl=ENSMODG00000007414.4\|UniProtKB=F7EE88	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000020955.3\|UniProtKB=F7G6A6	Ornithorhynchus anatinus	O
DANRE\|ZFIN=ZDB-GENE-040724-242\|UniProtKB=Q5RHZ0	Danio rerio	O
PIG\|Ensembl=ENSSSCG00005024903.1\|UniProtKB=A0A024BTL2	Sus scrofa	LDO
CANLF\|Ensembl=ENSCAFG00845013041.1\|UniProtKB=A0A8I3RZU2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000043196.1\|UniProtKB=A0A5F8H1W5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000010442.4\|UniProtKB=F6TC62	Ornithorhynchus anatinus	LDO
DANRE\|Gene=zmp=0000000881\|UniProtKB=A0A8M1RKR9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005019.1\|UniProtKB=W5MCD3	lepisosteus oculatus	LDO
STRPU\|EnsemblGenome=LOC582497\|UniProtKB=A0A7M7PA13	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00006993\|UniProtKB=Q95QC4	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG18173\|UniProtKB=A8XT66	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00111361\|UniProtKB=A0A2A6CZS1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00107447\|UniProtKB=A0A2A6C9N8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0011754\|UniProtKB=Q9I7D0	Drosophila melanogaster	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_303518\|UniProtKB=E9HR59	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW015509\|UniProtKB=B7QMZ0	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g94804\|UniProtKB=A7RV77	Nematostella vectensis	LDO
EREGS\|EnsemblGenome=AGOS_AFL188C\|UniProtKB=Q755K5	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000178305\|UniProtKB=A0A1D8PP50	Candida albicans	LDO
EMENI\|EnsemblGenome=ANIA_04279\|UniProtKB=C8V3Z7	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_7G00530\|UniProtKB=Q4WA97	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_7G03750\|UniProtKB=Q4WG46	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU02814\|UniProtKB=Q7SEK0	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_04069\|UniProtKB=A7EFH8	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03701\|UniProtKB=Q0UX13	Phaeosphaeria nodorum	LDO
ENTH1\|EnsemblGenome=CL6EHI_004470\|UniProtKB=C4LYQ8	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_004390\|UniProtKB=C4LYQ2	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_069290\|UniProtKB=C4LWL7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_075160\|UniProtKB=C4MA72	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_194420\|UniProtKB=C4LZV5	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_168060\|UniProtKB=C4M4Q3	Entamoeba histolytica	LDO
ENTH1\|EnsemblGenome=CL6EHI_151730\|UniProtKB=C4LSL4	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0280321\|UniProtKB=Q54VI1	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_29047\|UniProtKB=F0ZCY1	Dictyostelium purpureum	LDO
DICDI\|dictyBase=DDB_G0281567\|UniProtKB=P34101	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_57246\|UniProtKB=F0ZV38	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_157188\|UniProtKB=F0ZYH6	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_10_0830\|UniProtKB=Q4QHD1	Leishmania major	LDO
GIAIC\|EnsemblGenome=GL50803_4191\|UniProtKB=A8BQH5	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_480650\|UniProtKB=A2FLG5	Trichomonas vaginalis	LDO
PARTE\|EnsemblGenome=GSPATT00030806001\|UniProtKB=A0BNQ0	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00004832001\|UniProtKB=A0BIU3	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_5509\|UniProtKB=B8C341	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_23776\|UniProtKB=B8C710	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GRP4_PHYRM\|UniProtKB=H3GRP4	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_03g184450v5\|UniProtKB=A0A2K3DXY4	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g296200v5\|UniProtKB=A0A2K3DQS1	Chlamydomonas reinhardtii	LDO
MAIZE\|EnsemblGenome=Zm00001eb374320\|UniProtKB=K7W5N4	Zea mays	LDO
MAIZE\|EnsemblGenome=Zm00001eb374310\|UniProtKB=K7V640	Zea mays	LDO
ARATH\|Gene_OrderedLocusName=At3g63330\|UniProtKB=Q8RXY0	Arabidopsis thaliana	LDO
KLENI\|Gene_ORFName=KFL_006660010\|UniProtKB=A0A1Y1IR70	Klebsormidium nitens	LDO