PANTHER Gene Information   
Gene Symbol(s): Il6st
Organism: Rattus norvegicus
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Gene Name: Interleukin-6 receptor subunit beta
Gene ID: 2903
Protein ID: P40190
Persistent Id: PTN000547720
Alternate Ids:
M92340(EMBL) Oncostatin-M receptor subunit alpha(Synonym)
2903(RGD) 729835(GI)
Il6st{ECO:0000312|RGD:2903}(Symbol) IL6RB_RAT(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: CYTOKINE RECEPTOR (PTHR23036)
PANTHER Subfamily: INTERLEUKIN-6 RECEPTOR SUBUNIT BETA (PTHR23036:SF83)  
PANTHER GO-slim Molecular Function: cytokine receptor activity
cytokine binding
PANTHER GO-slim Biological Process: cytokine-mediated signaling pathway
PANTHER GO-slim Cellular Component: external side of plasma membrane
receptor complex
PANTHER protein class: transmembrane signal receptor
Pathway Categories: Interleukin signaling pathway
   Signaling subunit

GO MF Complete: coreceptor activity, growth factor binding, identical protein binding, cytokine receptor activity, ciliary neurotrophic factor receptor binding, interleukin-6 receptor binding, ciliary neurotrophic factor receptor activity, scaffold protein binding, interleukin-11 receptor activity, oncostatin-M receptor activity, leukemia inhibitory factor receptor activity, interleukin-6 receptor activity, interleukin-11 binding, interleukin-6 binding, protein tyrosine kinase activator activity, cytokine binding
GO BP Complete: response to cytokine, interleukin-11-mediated signaling pathway, oncostatin-M-mediated signaling pathway, signal transduction, regulation of Notch signaling pathway, positive regulation of cell population proliferation, negative regulation of cytosolic calcium ion concentration, response to nutrient, positive regulation of astrocyte differentiation, positive regulation of T cell proliferation, positive regulation of tyrosine phosphorylation of STAT protein, positive regulation of osteoblast differentiation, intestinal epithelial cell development, positive regulation of Notch signaling pathway, triglyceride mobilization, negative regulation of neuron apoptotic process, glycogen metabolic process, cytokine-mediated signaling pathway, leukemia inhibitory factor signaling pathway, ciliary neurotrophic factor-mediated signaling pathway, negative regulation of interleukin-6-mediated signaling pathway, interleukin-6-mediated signaling pathway, positive regulation of smooth muscle cell migration, interleukin-27-mediated signaling pathway
GO CC Complete: external side of plasma membrane, neuronal cell body membrane, receptor complex, neuronal cell body, plasma membrane, interleukin-6 receptor complex, dendrite, extracellular space, oncostatin-M receptor complex, membrane, cell body, membrane raft, ciliary neurotrophic factor receptor complex
Reactome Pathways: MAPK1 (ERK2) activation, MAPK3 (ERK1) activation, MAPK1/MAPK3 signaling, MAPK family signaling cascades, Signal Transduction, Interleukin-35 Signalling, Interleukin-12 family signaling, Signaling by Interleukins, Immune System, RAF-independent MAPK1/3 activation, Interleukin-27 signaling, Interleukin-6 family signaling, IL-6-type cytokine receptor ligand interactions, Cytokine Signaling in Immune system, Interleukin-6 signaling