PANTHER Gene Information

Gene Symbol(s):

PRK1

Organism:

Saccharomyces cerevisiae

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Gene Name:

Actin-regulating kinase PRK1

Gene ID:

S000001357

Protein ID:

P40494

Persistent Id:

PTN000540073

Alternate Ids:

YIL095W(Ensembl)	862488(GI)
U24167(EMBL)	CAA86699(EMBL-CDS)
PRK1(Symbol)	YIL095W_mRNA(Ensembl_TRS)
YIL095W(Ensembl_PRO)	PRK1(Synonym)
NP_012171(refSeq)	854713(GeneID)
2.7.11.1 {ECO:0000269\|PubMed:11739778, ECO:0000269\|PubMed:12956961, ECO:0000269\|PubMed:13679512, ECO:0000269\|PubMed:9885245}(EC)	YEAST:G3O-31354-MON(BioCyc)
PRK1_YEAST(UniProtKB-ID)	D6VVJ2(AltAccession)
S000001357(SGD)
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PANTHER Classification

PANTHER Family:	SERINE/THREONINE PROTEIN KINASE (PTHR22967)
PANTHER Subfamily:	AUXILIN, ISOFORM A-RELATED (PTHR22967:SF57)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	histone H3S10 kinase activity, histone H2BS14 kinase activity, histone H2AS1 kinase activity, protein kinase activity, eukaryotic translation initiation factor 2alpha kinase activity, protein serine/threonine kinase activity, 3-phosphoinositide-dependent protein kinase activity, ribosomal protein S6 kinase activity, DNA-dependent protein kinase activity, ATP binding, histone H2AT120 kinase activity, AMP-activated protein kinase activity, histone H2AS121 kinase activity, histone H3S57 kinase activity, histone H4S1 kinase activity, histone H3T3 kinase activity, histone H2BS36 kinase activity, histone H3S28 kinase activity, histone H3T45 kinase activity, histone H2AXS139 kinase activity, Rho-dependent protein serine/threonine kinase activity, histone H3T11 kinase activity, protein serine kinase activity, histone H3T6 kinase activity
GO BP Complete:	negative regulation of actin cortical patch assembly, chromatin remodeling, negative regulation of clathrin-dependent endocytosis, actin filament organization, negative regulation of protein-containing complex assembly, actin cortical patch assembly
GO CC Complete:	cytoskeleton, cytoplasm, mating projection tip, actin cortical patch

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
BRAFL\|Gene=LOC118432516\|UniProtKB=A0A9J7MEY7	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC762929\|UniProtKB=A0A7M7NAV5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC583309\|UniProtKB=A0A7M7PJ12	Strongylocentrotus purpuratus	O
PRIPA\|EnsemblGenome=WBGene00275401\|UniProtKB=A0A2A6BF13	Pristionchus pacificus	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g96644\|UniProtKB=A7RX98	Nematostella vectensis	O
ORNAN\|Ensembl=ENSOANG00000036315.1\|UniProtKB=A0A6I8P190	Ornithorhynchus anatinus	O
ORYLA\|Ensembl=ENSORLG00000008890.2\|UniProtKB=H2LYD9	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000011356.2\|UniProtKB=A0A3B3IHM2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-091118-25\|UniProtKB=A0A8M3B6K5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014966.1\|UniProtKB=W5NCR6	lepisosteus oculatus	O
HUMAN\|HGNC=18041\|UniProtKB=Q9NSY1	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000016203.6\|UniProtKB=H2RA65	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000023805.2\|UniProtKB=G3SHC3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011639.4\|UniProtKB=F6U9P8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2155456\|UniProtKB=Q91Z96	Mus musculus	LDO
RAT\|RGD=1564828\|UniProtKB=A0A8I6GK59	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000001126.6\|UniProtKB=A0A3Q1M6N5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000027722.4\|UniProtKB=I3LT15	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016099.3\|UniProtKB=F6TXI9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002953.6\|UniProtKB=M3VZG3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845016378.1\|UniProtKB=A0A8I3P813	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000020807.3\|UniProtKB=F6S7B5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003566.4\|UniProtKB=F7DGT6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010003165.1\|UniProtKB=E1C764	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006356.4\|UniProtKB=R4GBY1	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000017807.2\|UniProtKB=H2MU27	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041212-72\|UniProtKB=A0A0R4IUS2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007340.1\|UniProtKB=W5MKJ9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000001992.3\|UniProtKB=F6XG01	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118410835\|UniProtKB=A0A9J7KS71	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC753735\|UniProtKB=A0A7M7ND87	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00018516\|UniProtKB=Q20483	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00089165\|UniProtKB=B6IJ49	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004762\|UniProtKB=G5ECQ3	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG18039\|UniProtKB=A8XSW3	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00103856\|UniProtKB=A0A8R1YG10	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0037218\|UniProtKB=Q9VMY8	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0015772\|UniProtKB=Q9VJ30	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002469\|UniProtKB=Q5TTR9	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000132\|UniProtKB=D6WDD1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_328331\|UniProtKB=E9HCV3	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW023598\|UniProtKB=B7QLS5	Ixodes scapularis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_22473\|UniProtKB=A9UQP2	Monosiga brevicollis	LDO
EREGS\|EnsemblGenome=AGOS_ADL217W\|UniProtKB=Q75AY7	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000183416\|UniProtKB=Q5A961	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E22847g\|UniProtKB=W0TYM4	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_10515\|UniProtKB=C8V4L4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G05930\|UniProtKB=Q4WJH7	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU06202\|UniProtKB=Q7SBC1	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_07203\|UniProtKB=A7EPF4	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_11755\|UniProtKB=Q0U909	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCP1E11.02\|UniProtKB=Q9UU85	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04052\|UniProtKB=B6K5S6	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPBC557.04\|UniProtKB=Q9USS2	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04465\|UniProtKB=B6K6W5	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPBC6B1.02\|UniProtKB=O43066	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_00649\|UniProtKB=B6JW78	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNB03330\|UniProtKB=Q5KM16	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03081\|UniProtKB=A0A0D1CRA9	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_01774\|UniProtKB=E3JT06	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_92853\|UniProtKB=F4PEK4	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_103290\|UniProtKB=C4LVH4	Entamoeba histolytica	O
ENTH1\|Gene_ORFName=EHI_158080\|UniProtKB=A0A8U0WPF7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_030400\|UniProtKB=C4M453	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_127410\|UniProtKB=C4LX12	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0276461\|UniProtKB=Q86HW6	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_98203\|UniProtKB=F0ZNI0	Dictyostelium purpureum	LDO
DICDI\|dictyBase=DDB_G0280111\|UniProtKB=Q54VV7	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_95721\|UniProtKB=F0ZZW8	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_15_0770\|UniProtKB=Q4QFA8	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb09.160.4770\|UniProtKB=Q38ES8	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_12223\|UniProtKB=A8BPW2	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_213320\|UniProtKB=A2EEV7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_347840\|UniProtKB=A2DSS5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_144060\|UniProtKB=A2G0G1	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_475520\|UniProtKB=A2D9X6	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1247500\|UniProtKB=Q8I4V7	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00015625001\|UniProtKB=A0DCI0	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00012210001\|UniProtKB=A0D0U1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015448001\|UniProtKB=A0DC04	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_4105\|UniProtKB=B8C0Y2	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GI38_PHYRM\|UniProtKB=H3GI38	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g323100v5\|UniProtKB=A0A2K3DJ59	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00022p00186280\|UniProtKB=W1PV61	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_320G00050\|UniProtKB=A0A0K9P8Q6	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma07_g01980\|UniProtKB=A0A804JR63	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma04_g00610\|UniProtKB=A0A804IJI6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma03_g29720\|UniProtKB=A0A804IHT6	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_016569mg\|UniProtKB=K3YQM6	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G198600\|UniProtKB=C5XWF7	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb245770\|UniProtKB=A0A1D6HBX6	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb183460\|UniProtKB=K7U1D6	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0591900\|UniProtKB=Q69L76	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g47380v3\|UniProtKB=I1IB30	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0589870\|UniProtKB=M0ZBZ8	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G226000\|UniProtKB=A0A3B6PL42	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G189700\|UniProtKB=A0A3B6QGN3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G200200\|UniProtKB=A0A3B6NR56	Triticum aestivum	LDO
SETIT\|EnsemblGenome=SETIT_029095mg\|UniProtKB=K3ZR65	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G152200\|UniProtKB=A0A1B6QBL0	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb094370\|UniProtKB=A0A1D6EK57	Zea mays	O
BRADI\|EnsemblGenome=BRADI_4g26990v3\|UniProtKB=I1IP00	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0470980\|UniProtKB=F2DPI4	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5B02G170700\|UniProtKB=A0A3B6LJ78	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G173300\|UniProtKB=A0A3B6KH64	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G177800\|UniProtKB=A0A3B6MRM4	Triticum aestivum	O
NELNU\|Gene=LOC104597544\|UniProtKB=A0A1U7ZUY2	Nelumbo nucifera	O
NELNU\|Gene=LOC104603524\|UniProtKB=A0A1U8AFQ8	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110788115\|UniProtKB=A0A9R0IG96	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr17g0817971\|UniProtKB=A0A9K3DMC6	Helianthus annuus	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr17g0560591\|UniProtKB=A0A251RSV4	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400175290\|UniProtKB=A0A9R1VNM7	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a022935mg\|UniProtKB=A0A022QKT0	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_35384\|UniProtKB=A0A2G2XTF4	Capsicum annuum	LDO
CAPAN\|EnsemblGenome=T459_02482\|UniProtKB=A0A2G3AK73	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG402006333\|UniProtKB=M1A7A3	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc01g074010.3\|UniProtKB=A0A3Q7EH43	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107788132\|UniProtKB=A0A1S3ZLP5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107794886\|UniProtKB=A0A1S4A8G5	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi13g01805\|UniProtKB=F6HPW0	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_I00278\|UniProtKB=A0A059AKL9	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00061160001\|UniProtKB=A0A078FJ63	Brassica napus	O
BRACM\|EnsemblGenome=Bra005552\|UniProtKB=M4CMW4	Brassica campestris	O
BRACM\|EnsemblGenome=Bra022924\|UniProtKB=M4E2C4	Brassica campestris	LDO
ARATH\|TAIR=locus=2046462\|UniProtKB=Q8H0Z0	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107915630\|UniProtKB=A0A1U8KCN6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107950468\|UniProtKB=A0A1U8NP86	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_005941\|UniProtKB=A0A061DXG9	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g005558mg\|UniProtKB=A0A067E5A7	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G228100v3\|UniProtKB=A0A2K2C256	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_07G001200\|UniProtKB=A0A2C9VH63	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1771100\|UniProtKB=B9REI2	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_15G269800\|UniProtKB=I1MJK2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G150000\|UniProtKB=K7L6T7	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_3g026250\|UniProtKB=A0A072UVR8	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr14_00230\|UniProtKB=A0A2I4FRT4	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G702580\|UniProtKB=A0A0A0L9J9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G004800\|UniProtKB=A0A251Q8W8	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_98319\|UniProtKB=D8RP17	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_187420\|UniProtKB=D8TCP1	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c8_15370\|UniProtKB=A0A2K1K7D0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0022s0104\|UniProtKB=A0A2R6XD28	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000610180\|UniProtKB=A0A0U9HMR3	Klebsormidium nitens	LDO