PANTHER Gene Information

Gene Symbol(s):

PUS4

Organism:

Saccharomyces cerevisiae

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Gene Name:

tRNA pseudouridine synthase 4

Gene ID:

S000005236

Protein ID:

P48567

Persistent Id:

PTN000349208

Alternate Ids:

YNL292W(Ensembl_PRO)	tRNA pseudouridylate synthase 4(Synonym)
PUS4(Symbol)	855424(GeneID)
BK006947(EMBL)	YNL292W_mRNA(Ensembl_TRS)
YNL292W(Ensembl)	CAA96210(EMBL-CDS)
S000005236(SGD)	6324037(GI)
YEAST:YNL292W-MON(BioCyc)	5.4.99.25 {ECO:0000269\|PubMed:9358157}(EC)
NP_014107(refSeq)	PUS4_YEAST(UniProtKB-ID)
D6W0Q1(AltAccession)
Show All

PANTHER Classification

PANTHER Family:	TRNA-PSEUDOURIDINE SYNTHASE (PTHR13767)
PANTHER Subfamily:	PSEUDOURIDYLATE SYNTHASE TRUB1 (PTHR13767:SF2)
PANTHER GO-slim Molecular Function:	intramolecular transferase activity
PANTHER GO-slim Biological Process:	mRNA modification pseudouridine synthesis tRNA modification
PANTHER GO-slim Cellular Component:
PANTHER protein class:	isomerase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	tRNA pseudouridine(55) synthase activity, RNA binding, pseudouridine synthase activity, isomerase activity
GO BP Complete:	pseudouridine synthesis, tRNA processing, RNA processing, mRNA pseudouridine synthesis, tRNA modification
GO CC Complete:	nucleus, mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=16060\|UniProtKB=Q8WWH5	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000002964.4\|UniProtKB=K7CFC2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004583.3\|UniProtKB=G3QPK0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000001902.3\|UniProtKB=F7FWZ2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1919383\|UniProtKB=Q8C0D0	Mus musculus	LDO
RAT\|RGD=1308502\|UniProtKB=Q5M934	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000012955.6\|UniProtKB=E1BEB7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010653.5\|UniProtKB=A0A287AWV0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000007177.3\|UniProtKB=A0A9L0RGX8	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000031927.4\|UniProtKB=M3WVR4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845030859.1\|UniProtKB=A0A8I3SCV0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000009676.4\|UniProtKB=A0A5F8H3V1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000001556.3\|UniProtKB=A0A6I8PAT5	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000009282.4\|UniProtKB=H9GF07	Anolis carolinensis	LDO
XENLA\|Gene=trub1.L\|UniProtKB=A0A8J1L990	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1008962\|UniProtKB=A0A803J5Q4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000029719.1\|UniProtKB=A0A3B3HYU9	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-080723-73\|UniProtKB=B3DHG0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012979.1\|UniProtKB=W5N5S7	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118414978\|UniProtKB=A0A9J7L348	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC764958\|UniProtKB=A0A7M7NTQ1	Strongylocentrotus purpuratus	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_33293\|UniProtKB=E9FRC5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW021275\|UniProtKB=B7Q670	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG70692\|UniProtKB=T1G0A8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g5335\|UniProtKB=A7T9C1	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_13301\|UniProtKB=A9UQA2	Monosiga brevicollis	LDO
EREGS\|EnsemblGenome=AGOS_AEL198W\|UniProtKB=Q758G0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000191725\|UniProtKB=A0A1D8PN62	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D25234g\|UniProtKB=Q6C7U6	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00072\|UniProtKB=Q5BHA8	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G12310\|UniProtKB=Q4WVJ3	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU04153\|UniProtKB=Q1K7K6	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_11533\|UniProtKB=A7F1R2	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_13491\|UniProtKB=Q0U423	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_09940\|UniProtKB=Q0UE74	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC11C11.10\|UniProtKB=O59721	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04065\|UniProtKB=B6K5T9	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC01370\|UniProtKB=Q5KKZ0	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03057\|UniProtKB=A0A0D1CR96	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_10577\|UniProtKB=E3KIS4	Puccinia graminis	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_160185\|UniProtKB=F1A5V6	Dictyostelium purpureum	LDO
PLAF7\|EnsemblGenome=PF3D7_1018000\|UniProtKB=Q8I715	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_37374\|UniProtKB=B8CCU3	Thalassiosira pseudonana	LDO
CHLRE\|EnsemblGenome=CHLRE_16g690250v5\|UniProtKB=A0A2K3CU80	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00049p00225390\|UniProtKB=W1Q0X6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_15G00760\|UniProtKB=A0A0K9PUM8	Zostera marina	LDO
ZOSMR\|Gene_ORFName=ZOSMA_56G00480\|UniProtKB=A0A0K9NXP0	Zostera marina	O
MUSAM\|EnsemblGenome=Ma06_g08300\|UniProtKB=A0A804JDZ4	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_021882mg\|UniProtKB=K3Z5R4	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3009G007800\|UniProtKB=A0A1Z5R1C6	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb267110\|UniProtKB=A0A1D6LHY8	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os05g0108000\|UniProtKB=Q65X25	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g39361v3\|UniProtKB=A0A0Q3J607	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0003900\|UniProtKB=A0A8I6WPQ4	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1D02G024800\|UniProtKB=A0A3B5ZP14	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G024700\|UniProtKB=A0A3B5XTS3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G031100\|UniProtKB=A0A3B5YQT7	Triticum aestivum	LDO
NELNU\|Gene=LOC104593067\|UniProtKB=A0A1U7ZE01	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110805626\|UniProtKB=A0A9R0JF62	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0386741\|UniProtKB=A0A251TVN6	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400227550\|UniProtKB=A0A9R1XC81	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a004345mg\|UniProtKB=A0A022RW93	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_07080\|UniProtKB=A0A2G3ACK6	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400012609\|UniProtKB=M1AY56	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc02g093460.3\|UniProtKB=A0A3Q7FDR6	Solanum lycopersicum	LDO
VITVI\|EnsemblGenome=Vitvi14g01673\|UniProtKB=F6HUT7	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J02259\|UniProtKB=A0A059AG15	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C09P62720.1\|UniProtKB=A0A078F8Z9	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra008756\|UniProtKB=M4CX09	Brassica campestris	LDO
ARATH\|TAIR=locus=2145708\|UniProtKB=Q0WVR7	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107926046\|UniProtKB=A0A1U8LCG9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107897898\|UniProtKB=A0A1U8ILG0	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_016990\|UniProtKB=A0A061EC22	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g0097072mg\|UniProtKB=A0A067E1R5	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G343100v3\|UniProtKB=A0A2K2C824	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_17G111000\|UniProtKB=A0A2C9U8N5	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1065100\|UniProtKB=B9S669	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_05G002300\|UniProtKB=I1K1M6	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_6g004400\|UniProtKB=A0A072U4X6	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr10_03770\|UniProtKB=A0A2I4GRF3	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G522940\|UniProtKB=A0A0A0KP03	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G294000\|UniProtKB=M5WXR0	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_75554\|UniProtKB=D8QNU2	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_180168\|UniProtKB=D8SJ84	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c2_21370\|UniProtKB=A0A2K1L2I3	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0093s0080\|UniProtKB=A0A2R6WGP7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001810050\|UniProtKB=A0A1Y1HZY6	Klebsormidium nitens	LDO
CHLAA\|EnsemblGenome=Caur_3017\|UniProtKB=A9WGQ0	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO5709\|UniProtKB=Q9Z528	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv2793c\|UniProtKB=P9WHP7	Mycobacterium tuberculosis	LDO
CLOBH\|Gene_OrderedLocusName=CBO2416\|UniProtKB=A5I4J0	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr1092\|UniProtKB=Q8CWR2	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_01248\|UniProtKB=Q2G2Q3	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAC99406\|UniProtKB=Q8Y7F3	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_16660\|UniProtKB=P32732	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_3808\|UniProtKB=Q812X9	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_0856\|UniProtKB=Q9WZW0	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_1323\|UniProtKB=Q9RUQ9	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC91631\|UniProtKB=Q7MBB8	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA18814\|UniProtKB=P74696	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_0945\|UniProtKB=Q8CXU1	Leptospira interrogans	LDO
CHLTR\|EnsemblGenome=CT_094\|UniProtKB=O84096	Chlamydia trachomatis	LDO
RHOBA\|EnsemblGenome=RB6411\|UniProtKB=P59883	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_705\|UniProtKB=O66922	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0556\|UniProtKB=B5YJI4	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_1212\|UniProtKB=B8E2Z1	Dictyoglomus turgidum	LDO
FUSNN\|EnsemblGenome=FN0635\|UniProtKB=Q8R5X8	Fusobacterium nucleatum	LDO
NEIMB\|EnsemblGenome=NMB1374\|UniProtKB=Q9JYY1	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU1591\|UniProtKB=P60344	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC46046\|UniProtKB=Q89WB1	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_1430\|UniProtKB=Q4AAX7	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_1289\|UniProtKB=P45142	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_1206\|UniProtKB=K4PSE0	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_0645\|UniProtKB=Q9KU78	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC2509\|UniProtKB=Q8P7U9	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA4742\|UniProtKB=P72154	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM3284\|UniProtKB=Q8ZLT2	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_0589\|UniProtKB=Q8ZBC4	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAE77212\|UniProtKB=P60340	Escherichia coli	LDO