PANTHER Gene Information

Gene Symbol(s):

dia

Organism:

Drosophila melanogaster

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Gene Name:

Protein diaphanous

Gene ID:

FBgn0011202

Protein ID:

P48608

Persistent Id:

PTN000575576

Alternate Ids:

FBpp0307144(Ensembl_PRO)	NM_057633(refSeq)
35340(GeneID)	FBgn0011202(FlyBase)
DIA(Synonym)	575927(GI)
Q9VIJ7(AltAccession)	FBtr0081411(Ensembl_TRS)
dia(Symbol)	DIA_DROME(UniProtKB-ID)
AAN11087(EMBL-CDS)	FBgn0011202(Ensembl)
U11288(EMBL)
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PANTHER Classification

PANTHER Family:	PROTEIN DIAPHANOUS (PTHR45691)
PANTHER Subfamily:	PROTEIN DIAPHANOUS (PTHR45691:SF6)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	actin filament polymerization
PANTHER GO-slim Cellular Component:	actin filament
PANTHER protein class:	cytoskeletal protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	phosphatidylinositol-4,5-bisphosphate binding, protein binding, actin binding, small GTPase binding
GO BP Complete:	actomyosin contractile ring assembly, meiosis I cytokinesis, protein localization, actin filament organization, pole cell formation, meiosis II cytokinesis, salivary gland morphogenesis, mitotic cell cycle, embryonic, sensory perception of sound, plasma membrane tubulation, maintenance of protein location in cell, spindle assembly, regulation of filopodium assembly, mitotic cytokinesis, actin nucleation, regulation of embryonic cell shape, assembly of apicomedial cortex actomyosin, pseudocleavage involved in syncytial blastoderm formation, melanotic encapsulation of foreign target, positive regulation of wound healing, actin filament polymerization, sarcomere organization, apical constriction, cellularization, protein secretion, regulation of actomyosin structure organization, open tracheal system development, positive regulation of actin filament polymerization, actin cytoskeleton organization
GO CC Complete:	Z disc, apical part of cell, cytoplasm, cleavage furrow, cell cortex, vesicle membrane, cytoneme, protein-containing complex, M band, actin filament, apical plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2877\|UniProtKB=O60879	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000022082.6\|UniProtKB=H2R1G5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002859.4\|UniProtKB=G3QK53	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000020862.4\|UniProtKB=F7HNC0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1858500\|UniProtKB=O70566	Mus musculus	LDO
RAT\|RGD=15011308\|UniProtKB=A0A8I5ZLR9	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000050709.1\|UniProtKB=A0A3Q1MRR8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000012474.5\|UniProtKB=A0A5G2QFW7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011844.5\|UniProtKB=A0A3Q2KRZ0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000029591.4\|UniProtKB=A0A5F5XTD1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845026405.1\|UniProtKB=A0A8I3Q012	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002444.4\|UniProtKB=A0A5F8GRX4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000004201.4\|UniProtKB=A0A6I8NX37	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010018053.1\|UniProtKB=A0A8V0Z4F8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013498.3\|UniProtKB=H9GK55	Anolis carolinensis	LDO
XENLA\|Gene=diaph2.L\|UniProtKB=A0A8J0TAQ6	Xenopus laevis	LDO
XENTR\|Gene=diaph2\|UniProtKB=A0A8J1IQ35	Xenopus tropicalis	LDO
DANRE\|Gene=diaph2\|UniProtKB=A0A8M9PZW8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015338.1\|UniProtKB=W5NE24	lepisosteus oculatus	LDO
HUMAN\|HGNC=2876\|UniProtKB=O60610	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000045831.1\|UniProtKB=A0A2I3SFP3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002660.3\|UniProtKB=A0A2I2ZBM3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000021964.4\|UniProtKB=F6V4Y9	Macaca mulatta	O
MOUSE\|MGI=MGI=1194490\|UniProtKB=O08808	Mus musculus	O
RAT\|RGD=1310707\|UniProtKB=F1M775	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000030499.3\|UniProtKB=A0A3Q1LUD9	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000014387.5\|UniProtKB=A0A5G2QRI9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000020822.4\|UniProtKB=F6Y6I7	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000031011.4\|UniProtKB=A0A5F5Y676	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845015899.1\|UniProtKB=A0A8I3NMT6	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000010684.3\|UniProtKB=F7C147	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000050892.1\|UniProtKB=A0A6I8NW07	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000011971.4\|UniProtKB=A0A803TT96	Anolis carolinensis	O
XENLA\|Gene=diaph1.S\|UniProtKB=A0A8J1MTC1	Xenopus laevis	O
XENLA\|Gene=diaph1.L\|UniProtKB=A0A8J0UQ82	Xenopus laevis	O
XENTR\|Gene=diaph1\|UniProtKB=A0A8J1JCB0	Xenopus tropicalis	O
DANRE\|Gene=LOC101886015\|UniProtKB=A0A8M9QB73	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000011329.1\|UniProtKB=W5MZX3	lepisosteus oculatus	O
HUMAN\|HGNC=15480\|UniProtKB=Q9NSV4	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000005916.6\|UniProtKB=K7DBA3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001745.3\|UniProtKB=G3QH97	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000013780.4\|UniProtKB=F6Q0E6	Macaca mulatta	O
MOUSE\|MGI=MGI=1927222\|UniProtKB=Q9Z207	Mus musculus	O
RAT\|RGD=1593287\|UniProtKB=F1LVW7	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012443.7\|UniProtKB=E1BMN2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000009448.5\|UniProtKB=F1RJ64	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000019161.4\|UniProtKB=A0A3Q2HP41	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000027832.4\|UniProtKB=M3WQG3	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845019341.1\|UniProtKB=A0A8I3S1A7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000006363.5\|UniProtKB=A0A5F8GTY6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000006997.3\|UniProtKB=F7CXN1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010002406.1\|UniProtKB=A0A8V0XCP9	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004603.3\|UniProtKB=G1KDA5	Anolis carolinensis	O
XENLA\|Gene=diaph3.L\|UniProtKB=A0A8J0U842	Xenopus laevis	O
XENTR\|Gene=diaph3\|UniProtKB=A0A8J1J528	Xenopus tropicalis	O
LEPOC\|Ensembl=ENSLOCG00000004676.1\|UniProtKB=W5MBB1	lepisosteus oculatus	O
BRAFL\|Gene=LOC118418906\|UniProtKB=A0A9J7LEX2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC592122\|UniProtKB=A0A7M7SWJ3	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00000872\|UniProtKB=Q7JP75	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG16504\|UniProtKB=A8XPD1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00092481\|UniProtKB=A0A2A6CE92	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP009643\|UniProtKB=A0A1S4H2G7	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC006029\|UniProtKB=A0A139WDY6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_220427\|UniProtKB=E9FT11	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG192510\|UniProtKB=T1FU14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG86808\|UniProtKB=T1G6H1	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198008\|UniProtKB=A7RJG3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g171940\|UniProtKB=A7SLQ1	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG60005\|UniProtKB=B3S718	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_6002\|UniProtKB=A9URA4	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_24127\|UniProtKB=A9UVG5	Monosiga brevicollis	LDO
USTMA\|EnsemblGenome=UMAG_12254\|UniProtKB=A0A0D1CLP7	Ustilago maydis	LDO
ENTH1\|EnsemblGenome=CL6EHI_125300\|UniProtKB=C4M622	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_118260\|UniProtKB=C4LZ08	Entamoeba histolytica	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_154316\|UniProtKB=F0ZR10	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_148204\|UniProtKB=F0ZAI9	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_17_0930\|UniProtKB=Q4QE97	Leishmania major	LDO
TRIV3\|Gene_ORFName=TVAG_436740\|UniProtKB=A2DFC2	Trichomonas vaginalis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_bd811\|UniProtKB=B8LED2	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_263840\|UniProtKB=B8LC84	Thalassiosira pseudonana	O
CHLRE\|EnsemblGenome=CHLRE_10g424000v5\|UniProtKB=A0A2K3D9D7	Chlamydomonas reinhardtii	O