PANTHER Gene Information

Gene Symbol(s):

RNR2A

Organism:

Arabidopsis thaliana

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Gene Name:

Ribonucleoside-diphosphate reductase small chain A

Gene ID:

2088040

Protein ID:

P50651

Persistent Id:

PTN000601641

Alternate Ids:

BAB02776(EMBL-CDS)	23505945(GI)
1.17.4.1(EC)	RNR2(Synonym)
NM_113261(refSeq)	MetaCyc:AT3G23580-MON(BioCyc)
RIR2A_ARATH(UniProtKB-ID)	Q9LUH0(AltAccession)
AF372971(EMBL)	AT3G23580(Ensembl_TRS)
AT3G23580(Ensembl)	821937(GeneID)
locus:2088040(TAIR)	AT3G23580(Ensembl_PRO)
RNR2A(Symbol)
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PANTHER Classification

PANTHER Family:	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN (PTHR23409)
PANTHER Subfamily:	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN A (PTHR23409:SF35)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	reductase

Pathway Categories:

De novo pyrimidine deoxyribonucleotide biosynthesis

UDP reductase

De novo purine biosynthesis

GDP reductase

De novo pyrimidine deoxyribonucleotide biosynthesis

CDP Reductase

De novo purine biosynthesis

ADP reductase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO BP Complete:	DNA repair, multicellular organism development, ribonucleotide metabolic process, regulation of cell cycle
GO CC Complete:	cytoplasm, ribonucleoside-diphosphate reductase complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17296\|UniProtKB=Q7LG56	Homo sapiens	O
GORGO\|Ensembl=ENSGGOG00000003053.3\|UniProtKB=G3QKM4	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000020765.4\|UniProtKB=F7HEG5	Macaca mulatta	O
MOUSE\|MGI=MGI=2155865\|UniProtKB=Q6PEE3	Mus musculus	O
RAT\|RGD=1306045\|UniProtKB=D4ADQ1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000021208.5\|UniProtKB=E1BFQ8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000036139.3\|UniProtKB=A0A287BIW2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000006166.4\|UniProtKB=F7BM06	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000028214.4\|UniProtKB=M3X508	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845007500.1\|UniProtKB=A0A8I3N422	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000005993.4\|UniProtKB=F6SL91	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000001870.3\|UniProtKB=F7F6T1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010011915.1\|UniProtKB=A0A8V0YJX1	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000008913.4\|UniProtKB=G1KIC0	Anolis carolinensis	O
XENLA\|Gene=LOC108695407\|UniProtKB=A0A1L8FTL6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-970633\|UniProtKB=F7BGD2	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000013152.2\|UniProtKB=H2MD47	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030616-614\|UniProtKB=Q7ZYW0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009872.1\|UniProtKB=W5MUK8	lepisosteus oculatus	O
PANTR\|Ensembl=ENSPTRG00000050890.1\|UniProtKB=A0A2I3S4G3	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000011647.6\|UniProtKB=A0A2I3S028	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000027675.2\|UniProtKB=A0A2I2ZNB4	Gorilla gorilla gorilla	O
HUMAN\|HGNC=10452\|UniProtKB=P31350	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000042985.1\|UniProtKB=K7AZ73	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000040108.1\|UniProtKB=A0A2I2YNS8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000002057.4\|UniProtKB=F6WXL4	Macaca mulatta	O
MOUSE\|MGI=MGI=98181\|UniProtKB=P11157	Mus musculus	O
RAT\|RGD=1598310\|UniProtKB=Q4KLN6	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000008216.6\|UniProtKB=E1BI58	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000031741.3\|UniProtKB=A0A287ALY8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000007464.3\|UniProtKB=A0A3Q2L006	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000003942.5\|UniProtKB=M3W192	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845025952.1\|UniProtKB=A0A8I3PMS4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014763.4\|UniProtKB=A0A5F8GMM9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000005507.4\|UniProtKB=F6X694	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010002462.1\|UniProtKB=E1BXP4	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000112.4\|UniProtKB=G1K8A5	Anolis carolinensis	O
XENLA\|Gene=rrm2.1.L\|UniProtKB=Q6IP47	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-947052\|UniProtKB=F6VJ70	Xenopus tropicalis	O
XENLA\|Gene=rrm2.2.L\|UniProtKB=Q801Q4	Xenopus laevis	O
XENLA\|Gene=rrm2b.S\|UniProtKB=Q8AVY2	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-486925\|UniProtKB=Q68EP1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000020536.2\|UniProtKB=H2N1X7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000030298.1\|UniProtKB=A0A3B3HGN0	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-990415-25\|UniProtKB=P79733	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002000.1\|UniProtKB=W5M1R4	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000016838.1\|UniProtKB=W5NJK1	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000019148.1\|UniProtKB=F6TAK8	Ciona intestinalis	O
BRAFL\|Gene=LOC118432202\|UniProtKB=A0A9J7MFA0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418062\|UniProtKB=A0A9J7LCR1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409123\|UniProtKB=A0A9J7HV86	Branchiostoma floridae	O
BRAFL\|Gene=LOC118425643\|UniProtKB=A0A9J7N2C5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426915\|UniProtKB=A0A9J7M0Z4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422796\|UniProtKB=A0A9J7LSJ6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427594\|UniProtKB=A0A9J7M359	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419607\|UniProtKB=A0A9J7LGV0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423321\|UniProtKB=A0A9J7LS96	Branchiostoma floridae	O
BRAFL\|Gene=LOC118413425\|UniProtKB=A0A9J7KZJ5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410080\|UniProtKB=A0A9J7KNX6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411415\|UniProtKB=A0A9J7KSA5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420137\|UniProtKB=A0A9J7LHU0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118408546\|UniProtKB=A0A9J7HVB4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426150\|UniProtKB=A0A9J7M0X2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118428224\|UniProtKB=A0A9J7M4X2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429451\|UniProtKB=A0A9J7M6U1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118424713\|UniProtKB=A0A9J7LVX9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407631\|UniProtKB=A0A9J7KKU5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403887\|UniProtKB=A0A9J7HFR6	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC594140\|UniProtKB=A0A7M7PM70	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC577596\|UniProtKB=A0A7M7R9W0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004392\|UniProtKB=P42170	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00039246\|UniProtKB=A8XX72	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00275324\|UniProtKB=A0A2A6BG81	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00112008\|UniProtKB=A0A2A6CEM8	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0011704\|UniProtKB=P48592	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP006818\|UniProtKB=Q7QIF4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC013940\|UniProtKB=D6WNM5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_306462\|UniProtKB=E9FZ53	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW016837\|UniProtKB=B7PCI3	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG154313\|UniProtKB=T1ELE4	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g242355\|UniProtKB=A7S2C0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g148226\|UniProtKB=A7T6T9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g236860\|UniProtKB=A7S2C1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g165579\|UniProtKB=A7S2C2	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_15279\|UniProtKB=A9UU84	Monosiga brevicollis	O
YEAST\|SGD=S000003412\|UniProtKB=P49723	Saccharomyces cerevisiae	O
YEAST\|SGD=S000003563\|UniProtKB=P09938	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AAL136C\|UniProtKB=Q75F64	Eremothecium gossypii	O
CANAL\|CGD=CAL0000192458\|UniProtKB=A0A1D8PI17	Candida albicans	O
CANAL\|CGD=CAL0000188396\|UniProtKB=Q5A0L0	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B03630g\|UniProtKB=Q6CFU6	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_00067\|UniProtKB=Q5BHB3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G12350\|UniProtKB=Q4WVJ7	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU07887\|UniProtKB=Q9C167	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_03490\|UniProtKB=A7EDV0	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_10001\|UniProtKB=Q0UE13	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC25D12.04\|UniProtKB=P36603	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00885\|UniProtKB=B6JWW0	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNK01530\|UniProtKB=Q5K9L8	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNK02580\|UniProtKB=Q5K9A9	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_06368\|UniProtKB=A0A0D1DT07	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_17235\|UniProtKB=E3L338	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_37293\|UniProtKB=F4P948	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_16297\|UniProtKB=F4NZN2	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0272616\|UniProtKB=P42521	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_56591\|UniProtKB=F0ZS91	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_22_1290\|UniProtKB=Q4QBL8	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_27_2050\|UniProtKB=E9ADI5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.v4.0005\|UniProtKB=Q382Q2	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb11.v4.0004\|UniProtKB=Q382Q3	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb11.v4.0007\|UniProtKB=Q382Q0	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb11.v4.0006\|UniProtKB=Q382Q1	Trypanosoma brucei	O
PLAF7\|EnsemblGenome=PF3D7_1015800\|UniProtKB=Q8IJN8	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1405600\|UniProtKB=Q8IM38	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00020567001\|UniProtKB=A0DV38	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027296001\|UniProtKB=A0EI28	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_32555\|UniProtKB=B8BWW6	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_33670\|UniProtKB=B8BZD2	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_8522\|UniProtKB=B8C9R1	Thalassiosira pseudonana	O
PHYRM\|Gene=H3G8X8_PHYRM\|UniProtKB=H3G8X8	Phytophthora ramorum	O
PHYRM\|Gene=H3G5F5_PHYRM\|UniProtKB=H3G5F5	Phytophthora ramorum	O
PHYRM\|Gene=H3G7K6_PHYRM\|UniProtKB=H3G7K6	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_12g509400v5\|UniProtKB=A8IKH1	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00025p00110680\|UniProtKB=W1PX26	Amborella trichopoda	LDO
NELNU\|Gene=LOC104612844\|UniProtKB=A0A1U8BBQ3	Nelumbo nucifera	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0527341\|UniProtKB=A0A251SZP3	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C500256800\|UniProtKB=A0A9R1XAT9	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a009280mg\|UniProtKB=A0A022S035	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_02770\|UniProtKB=A0A1U8ECB0	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc01g080210.3\|UniProtKB=A0A3Q7EHT3	Solanum lycopersicum	LDO
VITVI\|Gene_OrderedLocusName=VIT_06s0004g08010\|UniProtKB=D7SJJ4	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi05g00412\|UniProtKB=F6HDK8	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_B01150\|UniProtKB=A0A059D1E6	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C01P40170.1\|UniProtKB=A0A078FB41	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra014962\|UniProtKB=A0A3P6B6R7	Brassica campestris	LDO
GOSHI\|Gene=LOC107927807\|UniProtKB=A0A1U8LMK9	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_020494\|UniProtKB=A0A061ET75	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g0189482mg\|UniProtKB=A0A067G5G1	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_008G201500v3\|UniProtKB=B9HMC3	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_03G185700\|UniProtKB=A0A2C9W8W8	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0678140\|UniProtKB=B9RSS1	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_07G256200\|UniProtKB=Q9XE60	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g117370\|UniProtKB=A0A072USZ2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr12_12210\|UniProtKB=A0A2I4G9F5	Juglans regia	LDO
PRUPE\|EnsemblGenome=PRUPE_2G066500\|UniProtKB=A0A251QCF5	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_1G149900\|UniProtKB=M5XWG3	Prunus persica	LDO
SACS2\|EnsemblGenome=SSO2498\|UniProtKB=Q97VV7	Sulfolobus solfataricus	O
HALSA\|EnsemblGenome=VNG_2383G\|UniProtKB=Q9HMU4	Halobacterium salinarum	O
CHLAA\|EnsemblGenome=Caur_3331\|UniProtKB=A9WJQ1	Chloroflexus aurantiacus	O
MYCTU\|Gene_OrderedLocusName=Rv0233\|UniProtKB=P9WH69	Mycobacterium tuberculosis	O
MYCTU\|Gene_OrderedLocusName=Rv1981c\|UniProtKB=P9WH73	Mycobacterium tuberculosis	O
MYCTU\|Gene_OrderedLocusName=Rv3048c\|UniProtKB=P9WH71	Mycobacterium tuberculosis	O
MYCGE\|EnsemblGenome=MG_229\|UniProtKB=P47471	mycoplasma genitalium	O
CLOBH\|Gene_OrderedLocusName=CBO2813\|UniProtKB=A5I5P9	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr1066\|UniProtKB=Q8DPP8	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_00743\|UniProtKB=Q2G077	Staphylococcus aureus	O
BACSU\|EnsemblGenome=BSU_20040\|UniProtKB=O30601	Bacillus subtilis	O
BACSU\|EnsemblGenome=BSU_17390\|UniProtKB=P50621	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_1355\|UniProtKB=Q81G55	Bacillus cereus	O
DEIRA\|EnsemblGenome=DR_B0109\|UniProtKB=Q9RZL6	Deinococcus radiodurans	O
SYNY3\|Gene=P74732_SYNY3\|UniProtKB=P74732	Synechocystis	O
CHLTR\|EnsemblGenome=CT_828\|UniProtKB=O84835	Chlamydia trachomatis	O
AQUAE\|EnsemblGenome=aq_1505\|UniProtKB=O67475	Aquifex aeolicus	O
FUSNN\|EnsemblGenome=FN0103\|UniProtKB=Q8RH17	Fusobacterium nucleatum	O
HELPY\|EnsemblGenome=HP_0364\|UniProtKB=P55983	Helicobacter pylori	O
NEIMB\|EnsemblGenome=NMB1288\|UniProtKB=Q9JZ52	Neisseria meningitidis serogroup b	O
BRADU\|Gene=nrdB\|UniProtKB=Q89YE6	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_1554\|UniProtKB=Q83BF5	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_1660\|UniProtKB=P43755	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_2416\|UniProtKB=Q8EEG6	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1255\|UniProtKB=Q9KSK1	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC3985\|UniProtKB=Q8P3T4	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA1155\|UniProtKB=Q9I4I2	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM2278\|UniProtKB=P37427	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO1213\|UniProtKB=A0A2U2H410	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA16054\|UniProtKB=P69924	Escherichia coli	O