PANTHER Gene Information

Gene Symbol(s):

SerT

Organism:

Drosophila melanogaster

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Sodium-dependent serotonin transporter

Gene ID:

FBgn0010414

Protein ID:

P51905

Persistent Id:

PTN000178341

Alternate Ids:

AAL48645(EMBL-CDS)	Q9W177(AltAccession)
FBtr0343316(Ensembl_TRS)	SerT(Symbol)
AY071023(EMBL)	24762620(GI)
5HT transporter(Synonym)	FBpp0072269(Ensembl_PRO)
SC6A4_DROME(UniProtKB-ID)	NM_001299910(refSeq)
37895(GeneID)	FBgn0010414(FlyBase)
FBgn0010414(Ensembl)
Show All

PANTHER Classification

PANTHER Family:	SODIUM/CHLORIDE DEPENDENT TRANSPORTER (PTHR11616)
PANTHER Subfamily:	SODIUM-DEPENDENT SEROTONIN TRANSPORTER (PTHR11616:SF279)
PANTHER GO-slim Molecular Function:	solute:sodium symporter activity cation binding organic cyclic compound binding heterocyclic compound binding chloride transmembrane transporter activity
PANTHER GO-slim Biological Process:	sodium ion transmembrane transport organic hydroxy compound transport amino acid transport import into cell establishment of localization in cell neurotransmitter transport
PANTHER GO-slim Cellular Component:	synapse plasma membrane neuron projection
PANTHER protein class:	primary active transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	serotonin binding, monoamine transmembrane transporter activity, serotonin:sodium:chloride symporter activity
GO BP Complete:	serotonin uptake, serotonin transport, sodium ion transmembrane transport, amino acid transport, monoamine transport
GO CC Complete:	membrane, synapse, neuron projection, plasma membrane, axon, axon terminus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Neuronal System, Transmission across Chemical Synapses, Serotonin clearance from the synaptic cleft, Neurotransmitter clearance

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11050\|UniProtKB=P31645	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000008958.4\|UniProtKB=A0A2J8LIN5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011934.3\|UniProtKB=G3R8E1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003515\|UniProtKB=Q9MYX0	Macaca mulatta	O
MOUSE\|MGI=MGI=96285\|UniProtKB=Q60857	Mus musculus	O
RAT\|RGD=3714\|UniProtKB=P31652	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000019349\|UniProtKB=Q9XT49	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000017797.5\|UniProtKB=A0A287A458	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000017112.3\|UniProtKB=F6QG30	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005906.6\|UniProtKB=M3W4Y0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845012358.1\|UniProtKB=A0A8I3RX10	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000009884.3\|UniProtKB=F6VD16	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000012658.3\|UniProtKB=F7BTB1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010029709.1\|UniProtKB=F1NZ44	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000011633.4\|UniProtKB=H9GIA8	Anolis carolinensis	O
XENLA\|Gene=slc6a4.L\|UniProtKB=A0A1L8HD33	Xenopus laevis	O
XENLA\|Gene=slc6a4.S\|UniProtKB=A0A1L8H536	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-22062972\|UniProtKB=A0A6I8RCX3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000013932.2\|UniProtKB=H2MFU2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060314-1\|UniProtKB=Q1WGB5	Danio rerio	O
MONDO\|Ensembl=ENSMODG00000004252.4\|UniProtKB=F6TW41	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010021834.1\|UniProtKB=A0A8V0ZMG9	Gallus gallus	LDO
XENLA\|Gene=slc6a4l.S\|UniProtKB=A0A8J0U5C9	Xenopus laevis	O
XENLA\|Gene=slc6a4l.L\|UniProtKB=A0A1L8HZY0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-940268\|UniProtKB=F7B9G1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007234.2\|UniProtKB=H2LSK8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060314-2\|UniProtKB=B3DJ31	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004125.1\|UniProtKB=W5M977	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007757.3\|UniProtKB=F6XTN6	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118426454\|UniProtKB=A0A9J7M0B7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC586058\|UniProtKB=A0A7M7RGK1	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC115930059\|UniProtKB=A0A7M7PUB8	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003387\|UniProtKB=Q9N3C7	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00026922\|UniProtKB=A8WWE4	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00102288\|UniProtKB=A0A8R1YDC1	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP010621\|UniProtKB=A0A1S4H4H9	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002347\|UniProtKB=D7EJF2	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_310380\|UniProtKB=E9FTF7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_314292\|UniProtKB=E9G579	Daphnia pulex	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g229612\|UniProtKB=A7S7X6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g228010\|UniProtKB=A7RHF4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109800\|UniProtKB=A7S978	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g209454\|UniProtKB=A7SAX9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g209450\|UniProtKB=A7SAX5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g98540\|UniProtKB=A7RZ73	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g187148\|UniProtKB=A7S977	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g236066\|UniProtKB=A7SXK0	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG27813\|UniProtKB=B3S1L0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG61885\|UniProtKB=B3SC88	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG59280\|UniProtKB=B3S5C7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG59303\|UniProtKB=B3S4Q0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG33157\|UniProtKB=B3SC89	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG29421\|UniProtKB=B3S5D0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG34381\|UniProtKB=B3SE77	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG29105\|UniProtKB=B3S5D1	Trichoplax adhaerens	O
EMENI\|EnsemblGenome=ANIA_08966\|UniProtKB=C8VL87	Emericella nidulans	O
PHANO\|EnsemblGenome=SNOG_05834\|UniProtKB=Q0UQY0	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_04273\|UniProtKB=Q0UVE1	Phaeosphaeria nodorum	O
PLAF7\|EnsemblGenome=PF3D7_0209600\|UniProtKB=O96181	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1132500\|UniProtKB=Q8II40	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00003373001\|UniProtKB=A0DZD7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003369001\|UniProtKB=A0DZD3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005033001\|UniProtKB=A0BJE3	Paramecium tetraurelia	O
THEKO\|EnsemblGenome=TK1432\|UniProtKB=Q5JDK2	Thermococcus kodakaraensis	O
LEPIN\|EnsemblGenome=LA_1877\|UniProtKB=Q8F511	Leptospira interrogans	O
AQUAE\|EnsemblGenome=aq_2077\|UniProtKB=O67854	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A0808\|UniProtKB=B5YK84	Thermodesulfovibrio yellowstonii	O