PANTHER Gene Information

Gene Symbol(s):

cyn-8

Organism:

Caenorhabditis elegans

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Gene Name:

Peptidyl-prolyl cis-trans isomerase 8

Gene ID:

WBGene00000884

Protein ID:

P52016

Persistent Id:

PTN000116503

Alternate Ids:

181136(GeneID)	D1009(WormBase_TRS)
373218954(GI)	CE27892(WormBase_PRO)
Q95QQ0(AltAccession)	U31078(EMBL)
D1009.2(Ensembl_PRO)	WBGene00000884(WormBase)
cyn-8{ECO:0000312\|WormBase:D1009.2}(Symbol)	Cyclophilin-8 {ECO:0000303\|PubMed:8694762}(Synonym)
AAC47130(EMBL-CDS)	D1009.2(Ensembl_TRS)
5.2.1.8(EC)	WBGene00000884(Ensembl)
CYP8_CAEEL(UniProtKB-ID)	NM_077105(refSeq)
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PANTHER Classification

PANTHER Family:	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (PTHR11071)
PANTHER Subfamily:	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 8 (PTHR11071:SF427)
PANTHER GO-slim Molecular Function:	peptidyl-prolyl cis-trans isomerase activity peptide binding
PANTHER GO-slim Biological Process:	protein peptidyl-prolyl isomerization protein folding
PANTHER GO-slim Cellular Component:	mitochondrion
PANTHER protein class:	chaperone

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	cyclosporin A binding, peptidyl-prolyl cis-trans isomerase activity
GO BP Complete:	protein peptidyl-prolyl isomerization, protein folding
GO CC Complete:	nucleus, catalytic step 2 spliceosome, cytoplasm, intracellular membrane-bounded organelle

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
STRPU\|EnsemblGenome=LOC588808\|UniProtKB=A0A7M7NHM1	Strongylocentrotus purpuratus	LDO
CAEBR\|Gene_ORFName=CBG00248\|UniProtKB=A8WMJ7	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029281\|UniProtKB=A8X3M8	Caenorhabditis briggsae	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g168774\|UniProtKB=A7SBW4	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG49935\|UniProtKB=B3RML4	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG63331\|UniProtKB=B3S234	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_33074\|UniProtKB=A9V3D3	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_18666\|UniProtKB=A9UWT1	Monosiga brevicollis	O
YEAST\|SGD=S000004206\|UniProtKB=P53691	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADR087C\|UniProtKB=Q75A33	Eremothecium gossypii	O
CANAL\|CGD=CAL0000194711\|UniProtKB=A0A1D8PJ59	Candida albicans	O
CANAL\|CGD=CAL0000193303\|UniProtKB=Q5ACI8	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_C16775g\|UniProtKB=Q6CBP4	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_04583\|UniProtKB=Q5B4E7	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G02050\|UniProtKB=Q4WIF3	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03853\|UniProtKB=Q9P3X9	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_04988\|UniProtKB=A7EI46	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_05639\|UniProtKB=Q0URH5	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC1B3.03c\|UniProtKB=Q11004	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04352\|UniProtKB=B6K6L7	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNK00020\|UniProtKB=Q5KA10	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNF00430\|UniProtKB=P0CP80	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_06259\|UniProtKB=Q4P0V4	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_06366\|UniProtKB=E3K7Z7	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_17243\|UniProtKB=E3L346	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_19273\|UniProtKB=E3L9U3	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_21514\|UniProtKB=F4NTN7	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_6502\|UniProtKB=F4NUD5	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_083580\|UniProtKB=C4M942	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0280401\|UniProtKB=Q9UA41	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_34727\|UniProtKB=F0ZN79	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0283663\|UniProtKB=Q54QS2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_154821\|UniProtKB=F0ZSC6	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0282359\|UniProtKB=Q54SM3	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0269120\|UniProtKB=Q9TW32	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_58785\|UniProtKB=F1A2W1	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_90286\|UniProtKB=F1A1K2	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_36_3130\|UniProtKB=Q4Q1A6	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.1215\|UniProtKB=Q383Y4	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_22_1450\|UniProtKB=Q4QBK2	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.7.3430\|UniProtKB=Q57WF8	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_25_0910\|UniProtKB=O02614	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.03.0250\|UniProtKB=Q387G2	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_16_1200\|UniProtKB=Q4QEP7	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.8.5230\|UniProtKB=Q57UJ5	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_23_0050\|UniProtKB=Q4QBH1	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.8.2000\|UniProtKB=Q581Y2	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_33_1630\|UniProtKB=Q4Q424	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.5.1370\|UniProtKB=Q57VC6	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.2.1560\|UniProtKB=Q585R7	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.2.1680\|UniProtKB=Q585R9	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_277390\|UniProtKB=A2FTU8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_027250\|UniProtKB=A2F1H0	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_146960\|UniProtKB=A2DKZ9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_062520\|UniProtKB=A2DLL4	Trichomonas vaginalis	O
PHYRM\|Gene=H3GJP9_PHYRM\|UniProtKB=H3GJP9	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_01g037400v5\|UniProtKB=A0A2K3E769	Chlamydomonas reinhardtii	O
PLAF7\|EnsemblGenome=PF3D7_1202400\|UniProtKB=Q8I621	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1115600\|UniProtKB=Q8IIK8	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1215200\|UniProtKB=Q8I5Q4	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_0322000\|UniProtKB=Q76NN7	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00016578001\|UniProtKB=A0DFE8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016961001\|UniProtKB=A0DHQ7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00013677001\|UniProtKB=A0D5B2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012663001\|UniProtKB=A0D290	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00007087001\|UniProtKB=A0CDK9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012749001\|UniProtKB=A0D2H4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00013337001\|UniProtKB=A0D4A4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00023608001\|UniProtKB=A0E564	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020371001\|UniProtKB=A0DUI2	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_36243\|UniProtKB=B8C839	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_28199\|UniProtKB=B8C1W1	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPS_797\|UniProtKB=B5YLG8	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_37464\|UniProtKB=B8CC36	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_29244\|UniProtKB=B8C7H9	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GAB0_PHYRM\|UniProtKB=H3GAB0	Phytophthora ramorum	O
PHYRM\|Gene=H3H1Q3_PHYRM\|UniProtKB=H3H1Q3	Phytophthora ramorum	O
PHYRM\|Gene=H3G772_PHYRM\|UniProtKB=H3G772	Phytophthora ramorum	O
PHYRM\|Gene=H3G525_PHYRM\|UniProtKB=H3G525	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_10g417500v5\|UniProtKB=A0A2K3D8X0	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_01g047700v5\|UniProtKB=A8HN48	Chlamydomonas reinhardtii	O
SELML\|EnsemblGenome=SELMODRAFT_233315\|UniProtKB=D8S7M2	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_236001\|UniProtKB=D8T3Z6	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c7_8500\|UniProtKB=A9S1Y7	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c11_24900\|UniProtKB=A0A2K1JW70	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0031s0050\|UniProtKB=A0A2R6X7I5	Marchantia polymorpha	O
AMBTC\|EnsemblGenome=AMTR_s00009p00179330\|UniProtKB=W1NGK1	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_99G00500\|UniProtKB=A0A0K9NHA8	Zostera marina	O
SETIT\|EnsemblGenome=SETIT_031274mg\|UniProtKB=K3ZXE2	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3005G016550\|UniProtKB=A0A1Z5RG86	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3007G216700\|UniProtKB=C5YJ79	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3002G138800\|UniProtKB=C5X6M4	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb095470\|UniProtKB=A0A804MLJ7	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb133720\|UniProtKB=A0A804N472	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb300930\|UniProtKB=B6SRE7	Zea mays	O
ORYSJ\|EnsemblGenome=Os09g0571400\|UniProtKB=Q651B0	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g02000v3\|UniProtKB=I1HWJ7	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_4g38880v3\|UniProtKB=I1IT59	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0331420\|UniProtKB=M0WK44	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4A02G312600\|UniProtKB=A0A3B6HY81	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G001600\|UniProtKB=A0A3B6JEB6	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_021310\|UniProtKB=A0A1U8B291	Nelumbo nucifera	O
SPIOL\|Gene=LOC110804822\|UniProtKB=A0A9R0JE17	Spinacia oleracea	O
HELAN\|Gene_ORFName=HanXRQr2_Chr01g0040601\|UniProtKB=A0A9K3JYF2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0468291\|UniProtKB=A0A251T7P7	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900473960\|UniProtKB=A0A9R1UDU1	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a014900mg\|UniProtKB=A0A022PYD4	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_29844\|UniProtKB=A0A1U8EU36	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400028689\|UniProtKB=M1CSR8	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc11g006070.2\|UniProtKB=A0A3Q7IQ99	Solanum lycopersicum	O
TOBAC\|Gene=LOC107829132\|UniProtKB=A0A1S4DF31	Nicotiana tabacum	O
TOBAC\|Gene=LOC107781297\|UniProtKB=A0A1S3YZE8	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi14g00560\|UniProtKB=A5B709	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_B02139\|UniProtKB=A0A059D4E2	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_B02135\|UniProtKB=A0A059D3H3	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_A09P49060.1\|UniProtKB=A0A078GRH6	Brassica napus	O
BRACM\|EnsemblGenome=Bra007214\|UniProtKB=A0A3P5YS73	Brassica campestris	O
ARATH\|TAIR=locus=2078451\|UniProtKB=Q38867	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107920704\|UniProtKB=A0A1U8KUA4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107893597\|UniProtKB=A0A1U8IE84	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_026248\|UniProtKB=A0A061F2Q5	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g030603mg\|UniProtKB=A0A067EFK3	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_T051300v3\|UniProtKB=A9PA45	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_019G014700v3\|UniProtKB=A0A2K1WN00	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_09G149200\|UniProtKB=A0A2C9VAY5	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_08G137600\|UniProtKB=A0A251KDI2	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0608620\|UniProtKB=B9S7J2	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_03G251600\|UniProtKB=A0A0R4J318	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_19G249000\|UniProtKB=A0A0R0ETG1	Glycine max	O
MEDTR\|EnsemblGenome=MTR_7g116340\|UniProtKB=G7L2X1	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr11_10830\|UniProtKB=A0A2I4EXP0	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_1G690270\|UniProtKB=A0A0A0M0H2	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_6G348500\|UniProtKB=M5W0F8	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_115473\|UniProtKB=D8SF73	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c11_25670\|UniProtKB=A0A2K1JWA5	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c7_2790\|UniProtKB=A0A2K1KA24	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c6_24150\|UniProtKB=A0A2K1KGX0	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c12_5480\|UniProtKB=A9S8E8	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c7_6420\|UniProtKB=A0A2K1KAM7	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0001s0110\|UniProtKB=A0A2R6XVF0	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000860260\|UniProtKB=A0A1Y1HSP4	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_005120110\|UniProtKB=A0A1Y1IEK2	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000030280\|UniProtKB=A0A1Y1HKU1	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_003040050\|UniProtKB=A0A1Y1IEZ0	Klebsormidium nitens	O