PANTHER Gene Information

Gene Symbol(s):

Pgi

Organism:

Drosophila melanogaster

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Gene Name:

Glucose-6-phosphate isomerase

Gene ID:

FBgn0003074

Protein ID:

P52029

Persistent Id:

PTN000157889

Alternate Ids:

15291247(GI)	5.3.1.9(EC)
FBgn0003074(FlyBase)	35886(GeneID)
Phosphohexose isomerase(Synonym)	FBpp0087762(Ensembl_PRO)
FBtr0088680(Ensembl_TRS)	Pgi(Symbol)
NP_523663(refSeq)	AAA28804(EMBL-CDS)
U20575(EMBL)	Q0E9F0(AltAccession)
G6PI_DROME(UniProtKB-ID)	FBgn0003074(Ensembl)
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PANTHER Classification

PANTHER Family:	GLUCOSE-6-PHOSPHATE ISOMERASE (PTHR11469)
PANTHER Subfamily:	GLUCOSE-6-PHOSPHATE ISOMERASE (PTHR11469:SF1)
PANTHER GO-slim Molecular Function:	monosaccharide binding isomerase activity
PANTHER GO-slim Biological Process:	hexose biosynthetic process glucose metabolic process glycolytic process glucose 6-phosphate metabolic process
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	isomerase

Pathway Categories:

Pentose phosphate pathway

Glucose-P-Isomerase

Glycolysis

Phosphoglucose isomerase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	glucose-6-phosphate isomerase activity, carbohydrate derivative binding, monosaccharide binding
GO BP Complete:	gluconeogenesis, glucose 6-phosphate metabolic process, glycolytic process, glucose homeostasis, fructose 6-phosphate metabolic process, canonical glycolysis
GO CC Complete:	cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Glycolysis, Metabolism of carbohydrates, Generic Transcription Pathway, Immune System, Transcriptional Regulation by TP53, Gene expression (Transcription), Gluconeogenesis, Metabolism, Glucose metabolism, TP53 Regulates Metabolic Genes, Innate Immune System, RNA Polymerase II Transcription, Neutrophil degranulation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4458\|UniProtKB=P06744	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000010816.6\|UniProtKB=A0A2I3TJX5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000016932.3\|UniProtKB=G3RPM0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005880.4\|UniProtKB=A0A5F8ANM2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=95797\|UniProtKB=P06745	Mus musculus	LDO
RAT\|RGD=2727\|UniProtKB=Q6P6V0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000006396\|UniProtKB=Q3ZBD7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000002873\|UniProtKB=P08059	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000018093.4\|UniProtKB=A0A9L0SXU9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005278.6\|UniProtKB=A0A337S9I7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845003009.1\|UniProtKB=A0A8I3MNX6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000011980.3\|UniProtKB=F7B9J9	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009577.4\|UniProtKB=F7BGD9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010009385.1\|UniProtKB=A0A8V0XXA9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001111.3\|UniProtKB=H9G532	Anolis carolinensis	LDO
XENLA\|Gene=gpi.S\|UniProtKB=Q6GP33	Xenopus laevis	O
XENLA\|Gene=gpi.L\|UniProtKB=A0A1L8GL32	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-944058\|UniProtKB=F6ZHL4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000000249.2\|UniProtKB=H2L3I7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-020513-2\|UniProtKB=Q8QFU2	Danio rerio	LDO
ORYLA\|Ensembl=ENSORLG00000014082.2\|UniProtKB=A0A3B3H9P7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-020513-3\|UniProtKB=Q0IJ39	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002085.1\|UniProtKB=W5M225	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118418022\|UniProtKB=A0A9J7LCX9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC764863\|UniProtKB=A0A7M7NA38	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC762939\|UniProtKB=A0A7M7G0F4	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00013597\|UniProtKB=Q7K707	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG08037\|UniProtKB=A8X5M7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00112519\|UniProtKB=A0A2A6CCS4	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP012167\|UniProtKB=Q7PVA2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC030755\|UniProtKB=D6WS20	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_302344\|UniProtKB=E9GCK2	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW014868\|UniProtKB=B7QLH6	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG109256\|UniProtKB=T1EES0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g189712\|UniProtKB=A7SGU1	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG19465\|UniProtKB=B3RJ35	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_34352\|UniProtKB=A9VB42	Monosiga brevicollis	LDO
YEAST\|SGD=S000000400\|UniProtKB=P12709	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AEL249C\|UniProtKB=Q758L0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000197690\|UniProtKB=P83780	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F07711g\|UniProtKB=Q6C2I1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_06037\|UniProtKB=Q5B093	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G09790\|UniProtKB=Q4X1J1	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU07281\|UniProtKB=Q7S986	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_14456\|UniProtKB=A7FA25	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_13608\|UniProtKB=Q0U3Q6	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC1604.05\|UniProtKB=P78917	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_00839\|UniProtKB=B6JWR1	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNB04050\|UniProtKB=Q5KLU5	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_15008\|UniProtKB=A0A0D1DUK2	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_07534\|UniProtKB=E3KDC8	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_36092\|UniProtKB=F4PCF8	Batrachochytrium dendrobatidis	LDO
ENTH1\|Gene_ORFName=EHI_047730\|UniProtKB=A0A8U0WP53	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0283673\|UniProtKB=Q5V9E9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_93752\|UniProtKB=F0ZB67	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_12_0530\|UniProtKB=Q4QGN9	Leishmania major	LDO
TRYB2\|Gene_ORFName=TB927.1.3830\|UniProtKB=Q4GYJ4	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_9115\|UniProtKB=E2RTY6	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_389760\|UniProtKB=A2E178	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_061930\|UniProtKB=A2E7V8	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1436000\|UniProtKB=Q8ILA4	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00011294001\|UniProtKB=A0CXZ5	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_39973\|UniProtKB=B8BYC8	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_270302\|UniProtKB=B8LC54	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_270301\|UniProtKB=B8C0P8	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G8D0_PHYRM\|UniProtKB=H3G8D0	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_03g175400v5\|UniProtKB=A8IE23	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00111p00094320\|UniProtKB=W1NX29	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_123G00140\|UniProtKB=A0A0K9Q069	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma10_g28640\|UniProtKB=A0A804L1C9	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma07_g08070\|UniProtKB=A0A804JTG8	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_034932mg\|UniProtKB=K4A7S6	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G071800\|UniProtKB=A0A1B6QHQ8	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb059230\|UniProtKB=P49105	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0776000\|UniProtKB=P42862	Oryza sativa	O
ORYSJ\|Gene_OrderedLocusName=LOC_Os06g14510\|UniProtKB=P42863	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g37400v3\|UniProtKB=I1HMC6	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0007200\|UniProtKB=F2CZQ3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1A02G040600\|UniProtKB=A0A3B5XU98	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G041200\|UniProtKB=A0A3B5ZN99	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G053600\|UniProtKB=A0A3B5YSL1	Triticum aestivum	LDO
NELNU\|Gene=LOC104601885\|UniProtKB=A0A1U8A8L1	Nelumbo nucifera	LDO
NELNU\|Gene_ORFName=HUJ06_015025\|UniProtKB=A0A1U7ZNH2	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110801368\|UniProtKB=A0A9R0J6N4	Spinacia oleracea	LDO
SPIOL\|Gene=PGIC\|UniProtKB=O82059	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0406301\|UniProtKB=A0A251TZM5	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400203610\|UniProtKB=A0A9R1XLM8	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a003701mg\|UniProtKB=A0A022RXA9	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_08743\|UniProtKB=A0A2G2ZXC6	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc12g014380.2\|UniProtKB=A0A3Q7J5N2	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107825825\|UniProtKB=A0A1S4D4C8	Nicotiana tabacum	O
TOBAC\|Gene=LOC107811651\|UniProtKB=A0A1S4BT89	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi18g00953\|UniProtKB=E0CQ39	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F01561\|UniProtKB=A0A059BQ23	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00041222001\|UniProtKB=A0A078JFK9	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra027452\|UniProtKB=M4EF90	Brassica campestris	LDO
ARATH\|TAIR=locus=2165462\|UniProtKB=P34795	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107922074\|UniProtKB=A0A1U8KY82	Gossypium hirsutum	O
GOSHI\|Gene=LOC107918028\|UniProtKB=A0A1U8KPU1	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_034022\|UniProtKB=A0A061FBP4	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g007374mg\|UniProtKB=A0A067GXU2	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_008G118900v3\|UniProtKB=B9HJ12	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_18G027800\|UniProtKB=A0A2C9U0U0	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_05G160800\|UniProtKB=A0A2C9VZ04	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1594100\|UniProtKB=B9R7S8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_04G032600\|UniProtKB=I1JTB8	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_19G017200\|UniProtKB=K7MVZ6	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_6g009330\|UniProtKB=G7KJZ8	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr06_08810\|UniProtKB=A0A2I4F4W8	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_2G361580\|UniProtKB=A0A0A0LLF4	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G380500\|UniProtKB=A0A251R9S2	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_409075\|UniProtKB=D8R9C6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_104526\|UniProtKB=D8RXP9	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_89539\|UniProtKB=D8RBX5	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c5_3820\|UniProtKB=A9S1G3	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c25_1860\|UniProtKB=A0A2K1IDG8	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c6_18070\|UniProtKB=A0A2K1KG59	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c16_6380\|UniProtKB=A0A7I4B9Z0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0034s0044\|UniProtKB=A0A2R6X5T3	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_006330030\|UniProtKB=A0A1Y1INL5	Klebsormidium nitens	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_38266\|UniProtKB=B8LDA5	Thalassiosira pseudonana	O
METJA\|EnsemblGenome=MJ_1605\|UniProtKB=Q59000	Methanocaldococcus jannaschii	LDO
HALSA\|EnsemblGenome=VNG_1992G\|UniProtKB=Q9HNQ6	Halobacterium salinarum	LDO
CHLAA\|EnsemblGenome=Caur_2179\|UniProtKB=A9WFP0	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO6659\|UniProtKB=O88015	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO1942\|UniProtKB=Q9Z523	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv0946c\|UniProtKB=P9WN69	Mycobacterium tuberculosis	LDO
MYCGE\|EnsemblGenome=MG_111\|UniProtKB=P47357	mycoplasma genitalium	LDO
CLOBH\|Gene_OrderedLocusName=CBO3278\|UniProtKB=A5I705	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr1882\|UniProtKB=Q8DN74	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_00900\|UniProtKB=Q2FZU0	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAD00445\|UniProtKB=Q8Y4R7	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_31350\|UniProtKB=P80860	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_4898\|UniProtKB=Q816G0	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_1385\|UniProtKB=Q9X1A5	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_1742\|UniProtKB=Q9RTL8	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC89633\|UniProtKB=Q7NJY9	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA18168\|UniProtKB=P52983	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_3888\|UniProtKB=Q8EZG6	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_2124\|UniProtKB=Q8A5W2	Bacteroides thetaiotaomicron	LDO
CHLTR\|EnsemblGenome=CT_378\|UniProtKB=P0CD72	Chlamydia trachomatis	LDO
RHOBA\|EnsemblGenome=RB399\|UniProtKB=Q7UYT0	Rhodopirellula baltica	LDO
THEYD\|EnsemblGenome=THEYE_A0152\|UniProtKB=B5YHI1	Thermodesulfovibrio yellowstonii	LDO
FUSNN\|EnsemblGenome=FN2054\|UniProtKB=Q8RHH5	Fusobacterium nucleatum	LDO
GEOSL\|EnsemblGenome=GSU1311\|UniProtKB=Q74DK5	Geobacter sulfurreducens	LDO
COXBU\|EnsemblGenome=CBU_0848\|UniProtKB=Q83D91	Coxiella burnetii	LDO
SHEON\|Gene_OrderedLocusName=SO_3547\|UniProtKB=Q8EBH1	Shewanella oneidensis	LDO
XANCP\|EnsemblGenome=XCC1771\|UniProtKB=Q8P9S7	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA4732\|UniProtKB=Q9HV67	Pseudomonas aeruginosa	LDO