PANTHER Gene Information

Gene Symbol(s):

PNP

Organism:

Bos taurus

View Gene in Tree

Tree

Gene Name:

Purine nucleoside phosphorylase

Gene ID:

PNP

Protein ID:

P55859

Persistent Id:

PTN007547016

Alternate Ids:

Q58DQ2(AltAccession)	2.4.2.1 {ECO:0000250\|UniProtKB:P00491}(EC)
AAI03292(EMBL-CDS)	34809932(GI)
NP(Synonym)	PNPH_BOVIN(UniProtKB-ID)
BT021545(EMBL)	PNP(Symbol)
CHEMBL2935(ChEMBL)
Show All

PANTHER Classification

PANTHER Family:	METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE (PTHR11904)
PANTHER Subfamily:	PURINE NUCLEOSIDE PHOSPHORYLASE (PTHR11904:SF12)
PANTHER GO-slim Molecular Function:	pentosyltransferase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	nucleotide kinase

Pathway Categories:

Xanthine and guanine salvage pathway

Guanosine phosphorylase

Purine metabolism

Nucleoside Phosphorylase

Adenine and hypoxanthine salvage pathway

Deoxyinosine phosphorylase

Xanthine and guanine salvage pathway

Deoxyguanosine phosphorylase

Adenine and hypoxanthine salvage pathway

Adenine phosphorylase

Adenine and hypoxanthine salvage pathway

Inosine phosphorylase

Adenine and hypoxanthine salvage pathway

Deoxyadenosine phosphorylase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	guanosine phosphorylase activity, purine-nucleoside phosphorylase activity
GO BP Complete:	purine ribonucleoside salvage
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7892\|UniProtKB=P00491	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006095.6\|UniProtKB=H2Q7W4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002126.3\|UniProtKB=G3SH63	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000017109.3\|UniProtKB=F7H566	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000019126.4\|UniProtKB=H9EX88	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97365\|UniProtKB=P23492	Mus musculus	LDO
MOUSE\|MGI=MGI=3712328\|UniProtKB=Q9D8C9	Mus musculus	LDO
RAT\|RGD=1597189\|UniProtKB=P85973	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000002135.5\|UniProtKB=F1S8H8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000045968.1\|UniProtKB=A0A3Q2HRQ0	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000019585.3\|UniProtKB=A0A5F5PXE6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006934.6\|UniProtKB=M3W6S5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023005.1\|UniProtKB=A0A8I3PDN5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000038369.1\|UniProtKB=A0A5F8GRI2	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000024346.1\|UniProtKB=F7B5G2	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000007053.3\|UniProtKB=F6VQN8	Monodelphis domestica	LDO
MONDO\|Ensembl=ENSMODG00000044465.1\|UniProtKB=A0A5F8HE50	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000043005.1\|UniProtKB=F7BHZ8	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000037707.1\|UniProtKB=A0A5F8H5Y1	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000023306.1\|UniProtKB=F6VAU4	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000025343.2\|UniProtKB=F6ZAU2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011206.3\|UniProtKB=F7FJA9	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000008033.3\|UniProtKB=H9GDE3	Anolis carolinensis	LDO
XENLA\|Gene=pnp.L\|UniProtKB=A0A1L8HZH9	Xenopus laevis	O
XENLA\|Gene=pnp.S\|UniProtKB=A0A1L8HPU5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1011598\|UniProtKB=Q6DIT1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000019273.2\|UniProtKB=H2MYC9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-1887\|UniProtKB=Q6P016	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010235.1\|UniProtKB=W5MVX6	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000002737.2\|UniProtKB=H2LBY1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000008292.2\|UniProtKB=H2LWB7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040912-54\|UniProtKB=Q66ID4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040426-2553\|UniProtKB=Q6NYG0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000000895.1\|UniProtKB=W5LXZ1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008086.3\|UniProtKB=F6Z6J2	Ciona intestinalis	O
BRAFL\|Gene=LOC118418716\|UniProtKB=A0A9J7MTN1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418065\|UniProtKB=A0A9J7MUV0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC585994\|UniProtKB=A0A7M7T0L1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC578392\|UniProtKB=A0A7M7HPP8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00019298\|UniProtKB=U4PSA1	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16977\|UniProtKB=A8XQ65	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00034258\|UniProtKB=A8XI15	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00096798\|UniProtKB=A0A2A6CBA9	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0034898\|UniProtKB=Q9W1K6	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0035348\|UniProtKB=M9PE19	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP005944\|UniProtKB=Q7PIK5	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP005945\|UniProtKB=A4Q998	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC006907\|UniProtKB=D7GY95	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC013184\|UniProtKB=D6WN16	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC003914\|UniProtKB=D6WHJ8	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_306029\|UniProtKB=E9GU60	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG91460\|UniProtKB=T1G841	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g207799\|UniProtKB=A7S700	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG51162\|UniProtKB=B3SCP0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55524\|UniProtKB=B3RV47	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55525\|UniProtKB=B3RV48	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_14617\|UniProtKB=A9URE9	Monosiga brevicollis	O
YEAST\|SGD=S000004199\|UniProtKB=Q05788	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ACR198W\|UniProtKB=Q75BS3	Eremothecium gossypii	O
CANAL\|CGD=CAL0000198365\|UniProtKB=A0A1D8PJL8	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F30129g\|UniProtKB=Q6BZX6	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_06490\|UniProtKB=C8V0B3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G05320\|UniProtKB=Q4WDN1	Neosartorya fumigata	O
PHANO\|EnsemblGenome=SNOG_09024\|UniProtKB=Q0UGU0	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC1805.16c\|UniProtKB=Q9UTG1	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01359\|UniProtKB=B6K0G6	Schizosaccharomyces japonicus	O
USTMA\|EnsemblGenome=UMAG_11207\|UniProtKB=A0A0D1DPW0	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_02143\|UniProtKB=E3JXA7	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_20130\|UniProtKB=E3LC31	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_15498\|UniProtKB=F4NVP5	Batrachochytrium dendrobatidis	O
GIAIC\|Gene_ORFName=GL50803_0091348\|UniProtKB=A0A644FBQ4	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_222920\|UniProtKB=A2FHY6	Trichomonas vaginalis	O
THAPS\|EnsemblGenome=THAPSDRAFT_29547\|UniProtKB=B8C8W1	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GH24_PHYRM\|UniProtKB=H3GH24	Phytophthora ramorum	O
PHYRM\|Gene=H3GH23_PHYRM\|UniProtKB=H3GH23	Phytophthora ramorum	O
PHYRM\|Gene=H3G995_PHYRM\|UniProtKB=H3G995	Phytophthora ramorum	O
CHLAA\|EnsemblGenome=Caur_2926\|UniProtKB=A9WFX1	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO4917\|UniProtKB=Q9EWV2	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv3307\|UniProtKB=P9WP01	Mycobacterium tuberculosis	O
CLOBH\|Gene_OrderedLocusName=CBO1864\|UniProtKB=A5I2Y7	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr0734\|UniProtKB=Q8CWS2	Streptococcus pneumoniae	O
LISMO\|Gene=pnp\|UniProtKB=Q8Y5V2	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_23490\|UniProtKB=P46354	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4086\|UniProtKB=Q819A0	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_1596\|UniProtKB=Q9X1T2	Thermotoga maritima	O
THEMA\|EnsemblGenome=TM_1737\|UniProtKB=Q9X259	Thermotoga maritima	O
BACTN\|EnsemblGenome=BT_1881\|UniProtKB=Q8A6K0	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB5437\|UniProtKB=Q7URV0	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB6588\|UniProtKB=Q7UQ11	Rhodopirellula baltica	O
COXBU\|EnsemblGenome=CBU_0016\|UniProtKB=Q83FC4	Coxiella burnetii	O
SALTY\|EnsemblGenome=STM2422\|UniProtKB=Q8ZN94	Salmonella typhimurium	O
YERPE\|EnsemblGenome=DBB30_19540\|UniProtKB=A0A384LKZ5	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA16275\|UniProtKB=P45563	Escherichia coli	O