PANTHER Gene Information   
Gene Symbol(s): WNT3
Organism: Homo sapiens
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Gene Name: Proto-oncogene Wnt-3
Gene ID: HGNC:12782
Protein ID: P56703
Enhancers: View enhancers for HUMAN|HGNC=12782|UniProtKB=P56703
Genetic Variant Annotation: Annoq
Persistent Id: PTN002485948
Alternate Ids:
AB067628(EMBL) AAI12117(EMBL-CDS)
WNT3(Symbol) ENST00000611547(Ensembl_TRS)
CHEMBL6079(ChEMBL) Proto-oncogene Int-4 homolog(Synonym)
ENSP00000225512(Ensembl_PRO) 273395(MIM)
7473(GeneID) HGNC:12782(HGNC)
NM_030753(refSeq) Q9H1J9(AltAccession)
ENSG00000277626(Ensembl) 85566796(GI)
WNT3_HUMAN(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: WNT RELATED (PTHR12027)
PANTHER Subfamily: PROTO-ONCOGENE WNT-3 (PTHR12027:SF82)  
PANTHER GO-slim Molecular Function: cytokine activity
G protein-coupled receptor binding
PANTHER GO-slim Biological Process: cell fate commitment
canonical Wnt signaling pathway
neuron differentiation
PANTHER GO-slim Cellular Component: extracellular space
PANTHER protein class: intercellular signal molecule
Pathway Categories: Alzheimer disease-presenilin pathway
   Wingless-type MMTV integration site family member
Cadherin signaling pathway
   Wingless-type MMTV integration site family member
Wnt signaling pathway
   Wingless-type MMTV integration site family member

GO MF Complete: frizzled binding, protein domain specific binding, protein binding, receptor ligand activity, cytokine activity
GO BP Complete: Spemann organizer formation at the anterior end of the primitive streak, axon guidance, gamete generation, dorsal/ventral axis specification, positive regulation of osteoblast differentiation, head morphogenesis, canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation, anterior/posterior axis specification, regulation of mesenchymal stem cell differentiation, stem cell proliferation, mammary gland epithelium development, canonical Wnt signaling pathway, mesoderm formation, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, neuron differentiation, cell morphogenesis, limb bud formation, negative regulation of axon extension involved in axon guidance, midbrain dopaminergic neuron differentiation, positive regulation of collateral sprouting in absence of injury, cellular response to retinoic acid, positive regulation of gene expression, cell fate commitment, gene expression, positive regulation of Wnt signaling pathway, regulation of neurogenesis
GO CC Complete: endoplasmic reticulum lumen, Wnt signalosome, extracellular space, extracellular exosome, extracellular matrix, extracellular region, Golgi lumen, plasma membrane, endocytic vesicle membrane
Reactome Pathways: Signal Transduction, Class B/2 (Secretin family receptors), TCF dependent signaling in response to WNT, Signaling by WNT, WNT ligand biogenesis and trafficking, Signaling by GPCR, GPCR ligand binding