PANTHER Gene Information

Gene Symbol(s):

Rasa2

Organism:

Mus musculus

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Gene Name:

Ras GTPase-activating protein 2

Gene ID:

MGI:2149960

Protein ID:

P58069

Persistent Id:

PTN000022991

Alternate Ids:

Rasa2(Symbol)	RASA2(Synonym)
AC161257(EMBL)	ENSMUST00000034984(Ensembl_TRS)
RASA2_MOUSE(UniProtKB-ID)	MGI:2149960(MGI)
NM_053268(refSeq)	G3X918(AltAccession)
ENSMUSG00000032413(Ensembl)	114158699(GI)
114713(GeneID)	BAB32975(EMBL-CDS)
ENSMUSP00000034984(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	RAS GTPASE-ACTIVATING PROTEINS (PTHR10194)
PANTHER Subfamily:	RAS GTPASE-ACTIVATING PROTEIN 2 (PTHR10194:SF21)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	GTPase-activating protein

Pathway Categories:

PDGF signaling pathway

Ras GTPase-Activating Protein

FGF signaling pathway

Ras GTPase-Activating Protein

EGF receptor signaling pathway

GTPase-Activating Protein

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metal ion binding, GTPase activator activity, phospholipid binding
GO BP Complete:	negative regulation of Ras protein signal transduction, intracellular signal transduction
GO CC Complete:	plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signal Transduction, MAPK1/MAPK3 signaling, Regulation of RAS by GAPs, MAPK family signaling cascades, RAF/MAP kinase cascade

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9872\|UniProtKB=Q15283	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000015472.4\|UniProtKB=H2QNH9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000023738.3\|UniProtKB=G3RXY5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009418.4\|UniProtKB=F6X9K0	Macaca mulatta	LDO
RAT\|RGD=3538\|UniProtKB=Q63713	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015413.6\|UniProtKB=F1N795	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000011672.5\|UniProtKB=A0A287B5R2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010845.4\|UniProtKB=A0A3Q2HPK1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002561.6\|UniProtKB=A0A2I2UFX2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845028112.1\|UniProtKB=A0A8I3PVQ4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000021230.4\|UniProtKB=F6U0L5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002775.2\|UniProtKB=A0A6I8P2V5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023887.1\|UniProtKB=A0A8V1A2A7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000005140.4\|UniProtKB=G1KDZ3	Anolis carolinensis	LDO
XENLA\|Gene=rasa2.L\|UniProtKB=A0A1L8GBH7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-480785\|UniProtKB=A0JP93	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000011646.2\|UniProtKB=H2M7Z2	Oryzias latipes	LDO
DANRE\|Gene=rasa2\|UniProtKB=A0A8M6Z2T9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000008121.1\|UniProtKB=W5MNB2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000012766.2\|UniProtKB=F6ZQ65	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118426920\|UniProtKB=A0A9J7M0Q1	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC763344\|UniProtKB=A0A7M7NK25	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001515\|UniProtKB=Q22720	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG14068\|UniProtKB=A8XJA2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00276815\|UniProtKB=A0A2A6CFD4	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0004390\|UniProtKB=P48423	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002261\|UniProtKB=Q7PTK8	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC014250\|UniProtKB=D6WKV4	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW002948\|UniProtKB=B7PCK6	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g241545\|UniProtKB=A7RYE3	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG63821\|UniProtKB=B3RUA9	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_33470\|UniProtKB=A9V5K0	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_32645\|UniProtKB=A9V0W1	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_35609\|UniProtKB=A9UQ94	Monosiga brevicollis	LDO
YEAST\|SGD=S000001575\|UniProtKB=P33314	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABR021W\|UniProtKB=Q75DK0	Eremothecium gossypii	O
CANAL\|CGD=CAL0000177461\|UniProtKB=A0A1D8PFE8	Candida albicans	O
CANAL\|CGD=CAL0000199838\|UniProtKB=Q5A506	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D23903g\|UniProtKB=Q6C802	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_03735\|UniProtKB=Q5B6U5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G12340\|UniProtKB=Q4WLU0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03852\|UniProtKB=Q7RW81	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_04989\|UniProtKB=A7EI47	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_05526\|UniProtKB=Q0URT8	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_05039\|UniProtKB=A0A0D1BZN3	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_11646\|UniProtKB=E3KNL5	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_11670\|UniProtKB=E3KNN9	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_92146\|UniProtKB=F4PCP2	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_156210\|UniProtKB=C4M4C1	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0271750\|UniProtKB=Q55AR6	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_79326\|UniProtKB=F0ZM90	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0282055\|UniProtKB=Q54T13	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_155156\|UniProtKB=F0ZT79	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0284177\|UniProtKB=Q54Q13	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_96454\|UniProtKB=F0Z8L5	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0277675\|UniProtKB=Q86JJ7	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_156697\|UniProtKB=F0ZX68	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0274211\|UniProtKB=Q8SSU4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_4386\|UniProtKB=F0Z641	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0278483\|UniProtKB=Q54Y08	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_160044\|UniProtKB=F1A5K7	Dictyostelium purpureum	O
TRIV3\|Gene_ORFName=TVAG_277960\|UniProtKB=A2DU37	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_059750\|UniProtKB=A2FB27	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_268180\|UniProtKB=A2DLG7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_232110\|UniProtKB=A2G2R5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_523070\|UniProtKB=A2GF60	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_254050\|UniProtKB=A2DMS2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_556880\|UniProtKB=A2GDU5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_281880\|UniProtKB=A2E9Q3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_419730\|UniProtKB=A2EIU7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_148180\|UniProtKB=A2FFI6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_118810\|UniProtKB=A2EAY4	Trichomonas vaginalis	O
PHYRM\|Gene=H3GMA0_PHYRM\|UniProtKB=H3GMA0	Phytophthora ramorum	O
PHYRM\|Gene=H3GJ72_PHYRM\|UniProtKB=H3GJ72	Phytophthora ramorum	O