PANTHER Gene Information

Gene Symbol(s):

Pitx1

Organism:

Mus musculus

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Gene Name:

Pituitary homeobox 1

Gene ID:

MGI:107374

Protein ID:

P70314

Persistent Id:

PTN000676481

Alternate Ids:

Pitx1(Symbol)	Homeobox protein P-OTX(Synonym)
U54499(EMBL)	ENSMUST00000021968(Ensembl_TRS)
ENSMUSG00000021506(Ensembl)	AAC52716(EMBL-CDS)
NP_035227(refSeq)	568983160(GI)
PITX1_MOUSE(UniProtKB-ID)	P70427(AltAccession)
18740(GeneID)	MGI:107374(MGI)
ENSMUSP00000021968(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	PITUITARY HOMEOBOX HOMOLOG PTX1 (PTHR45882)
PANTHER Subfamily:	PITUITARY HOMEOBOX 1 (PTHR45882:SF1)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	anatomical structure morphogenesis regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	homeodomain transcription factor

Pathway Categories:

Gonadotropin-releasing hormone receptor pathway

PITX

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA-binding transcription factor activity, protein binding, RNA polymerase II-specific DNA-binding transcription factor binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific double-stranded DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	skeletal system development, negative regulation of DNA-templated transcription, branchiomeric skeletal muscle development, myoblast fate commitment, regulation of DNA-templated transcription, anatomical structure morphogenesis, positive regulation of transcription by RNA polymerase II, hindlimb morphogenesis, embryonic hindlimb morphogenesis, regulation of transcription by RNA polymerase II, pituitary gland development, cartilage development
GO CC Complete:	nucleus, transcription regulator complex, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9004\|UniProtKB=P78337	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017254.5\|UniProtKB=A0A2J8LRP3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004846.3\|UniProtKB=G3QQ87	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000052860.1\|UniProtKB=A0A5F8A560	Macaca mulatta	LDO
RAT\|RGD=69253\|UniProtKB=Q99NA7	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000004602.6\|UniProtKB=F1MU46	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000061433.1\|UniProtKB=F8SIP6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014725.4\|UniProtKB=A0A9L0SH55	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000044399.2\|UniProtKB=A0A337SJR2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013882.1\|UniProtKB=A0A8I3NFW0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000048877.1\|UniProtKB=A0A5F8H975	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000031547.2\|UniProtKB=K7EBW3	Ornithorhynchus anatinus	LDO
ORNAN\|Ensembl=ENSOANG00000011172.2\|UniProtKB=F7FRV3	Ornithorhynchus anatinus	LDO
CHICK\|Gene=PITX1\|UniProtKB=P56673	Gallus gallus	LDO
XENLA\|Gene=pitx1\|UniProtKB=Q9W751	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-485441\|UniProtKB=Q68FA6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000024148.1\|UniProtKB=A0A3B3I6I8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060421-3623\|UniProtKB=A9Y0D5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010144.1\|UniProtKB=W5MVK8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005285.3\|UniProtKB=Q4H2Y1	Ciona intestinalis	O
BRAFL\|Gene=LOC118412402\|UniProtKB=A0A9J7KX10	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC576991\|UniProtKB=A0A7M7TG74	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592735\|UniProtKB=A0A7M7SWC3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC582509\|UniProtKB=A0A7M7RFF0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00006766\|UniProtKB=P52906	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00025006\|UniProtKB=A8WQQ9	Caenorhabditis briggsae	O
DROME\|FlyBase=FBgn0020912\|UniProtKB=O18400	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP000190\|UniProtKB=Q7PRW5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC032174\|UniProtKB=A0A139WMW8	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_331172\|UniProtKB=E9HLQ1	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG112977\|UniProtKB=T1EFP0	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g233675\|UniProtKB=A7SWM8	Nematostella vectensis	O