PANTHER Gene Information   
Gene Symbol(s): Gak
Organism: Rattus norvegicus
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Gene Name: Cyclin-G-associated kinase
Gene ID: 621589
Protein ID: P97874
Persistent Id: PTN000571076
Alternate Ids:
BAA18911(EMBL-CDS) GAK(Synonym)
13591947(GI) D38560(EMBL)
Gak(Symbol) 2.7.11.1(EC)
81659(GeneID) 621589(RGD)
NP_112292(refSeq) GAK_RAT(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED (PTHR23172)
PANTHER Subfamily: CYCLIN-G-ASSOCIATED KINASE (PTHR23172:SF34)  
PANTHER GO-slim Molecular Function: clathrin binding
PANTHER GO-slim Biological Process: protein depolymerization
clathrin-dependent endocytosis
PANTHER GO-slim Cellular Component: vesicle
cytoplasm
intracellular membrane-bounded organelle
PANTHER protein class: membrane traffic protein
Pathway Categories: No pathway information available
GO MF Complete: ATP binding, protein kinase activity, cyclin binding, clathrin binding, protein serine/threonine kinase activity, protein serine kinase activity
GO BP Complete: neuroepithelial cell differentiation, protein localization to Golgi apparatus, Golgi organization, intracellular transport, neural precursor cell proliferation, regulation of clathrin coat assembly, epithelial cell development, forebrain morphogenesis, endoplasmic reticulum organization, Golgi to lysosome transport, receptor-mediated endocytosis, establishment of skin barrier, clathrin-dependent endocytosis, keratinocyte differentiation, epidermal cell differentiation, stem cell differentiation, negative regulation of neuron projection development, clathrin coat assembly, positive regulation of neural precursor cell proliferation, intrahepatic bile duct development, clathrin coat disassembly, protein localization to plasma membrane
GO CC Complete: perinuclear region of cytoplasm, focal adhesion, cytoplasm, intracellular membrane-bounded organelle, cytosol, vesicle, Golgi apparatus, clathrin-coated vesicle
Reactome Pathways: Golgi Associated Vesicle Biogenesis, Vesicle-mediated transport, trans-Golgi Network Vesicle Budding, Membrane Trafficking, Clathrin-mediated endocytosis