PANTHER Gene Information

Gene Symbol(s):

ahpE

Organism:

Mycobacterium tuberculosis

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Tree

Gene Name:

Alkyl hydroperoxide reductase E

Gene ID:

Rv2238c

Protein ID:

P9WIE3

Persistent Id:

PTN002450011

Alternate Ids:

1.11.1.29 {ECO:0000269\|PubMed:19737009}(EC)	61680454(GI)
Q10520(AltAccession)	WP_003411527(refSeq)
CCP45018(EMBL-CDS)	AHPE_MYCTU(UniProtKB-ID)
ahpE(Symbol)	AL123456(EMBL)
887871(GeneID)	AHPE(Synonym)
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PANTHER Classification

PANTHER Family:	THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE (PTHR42801)
PANTHER Subfamily:	ALKYL HYDROPEROXIDE REDUCTASE E (PTHR42801:SF20)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on peroxide as acceptor antioxidant activity
PANTHER GO-slim Biological Process:	cellular response to oxidative stress cellular homeostasis
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	peroxidase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	peroxidase activity, protein binding, antioxidant activity, oxidoreductase activity, thioredoxin peroxidase activity, peroxiredoxin activity
GO BP Complete:	cellular oxidant detoxification, cellular response to oxidative stress, response to nitrosative stress, cell redox homeostasis
GO CC Complete:	cytoplasm, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Tolerance by Mtb to nitric oxide produced by macrophages, Bacterial Infection Pathways, Latent infection - Other responses of Mtb to phagocytosis, Infection with Mycobacterium tuberculosis, Disease, Infectious disease

Orthologs

ID	Organism	Type
PHANO\|EnsemblGenome=SNOG_11354\|UniProtKB=Q0UA60	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_03143\|UniProtKB=A0A0D1E1Z2	Ustilago maydis	O
YEAST\|SGD=S000001272\|UniProtKB=P40553	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADL018W\|UniProtKB=Q75AD5	Eremothecium gossypii	O
CANAL\|CGD=CAL0000195251\|UniProtKB=Q5A7P9	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E19448g\|UniProtKB=Q6C5B6	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_04301\|UniProtKB=C8V993	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G05915\|UniProtKB=A4D9N6	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU08931\|UniProtKB=V5IM08	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_03719\|UniProtKB=A7EEH9	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_05041\|UniProtKB=Q0UT73	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC1773.02c\|UniProtKB=O94561	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_02515\|UniProtKB=B6K2P9	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNC04710\|UniProtKB=Q5KK06	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_04851\|UniProtKB=A0A0D1DW78	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_18343\|UniProtKB=E3L733	Puccinia graminis	O
PLAF7\|EnsemblGenome=PF3D7_1027300\|UniProtKB=Q8IJD0	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00038266001\|UniProtKB=A0CGA4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00031127001\|UniProtKB=A0BQT1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012572001\|UniProtKB=A0D1Z9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00007266001\|UniProtKB=A0CE37	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00033616001\|UniProtKB=A0BYZ6	Paramecium tetraurelia	O
PHYRM\|Gene=H3GBX9_PHYRM\|UniProtKB=H3GBX9	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_02g095069v5\|UniProtKB=A0A2K3E1M8	Chlamydomonas reinhardtii	O
KLENI\|Gene_ORFName=KFL_002910160\|UniProtKB=A0A1Y1IEE6	Klebsormidium nitens	O
USTMA\|EnsemblGenome=UMAG_03211\|UniProtKB=A0A0D1C4S4	Ustilago maydis	O
DICDI\|dictyBase=DDB_G0279951\|UniProtKB=Q54W30	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0272280\|UniProtKB=Q559T9	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0275755\|UniProtKB=Q552Z0	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0269256\|UniProtKB=Q55EE4	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0268192\|UniProtKB=Q55FA7	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0269392\|UniProtKB=Q55E48	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0279949\|UniProtKB=B0G133	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0285273\|UniProtKB=Q54NG4	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0269260\|UniProtKB=Q55EF1	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0279973\|UniProtKB=Q54W09	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_25457\|UniProtKB=F0Z6X9	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_58311\|UniProtKB=F1A0D5	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_81218\|UniProtKB=F0ZSU5	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_79975\|UniProtKB=F0ZP67	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_92295\|UniProtKB=F0ZPS5	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_92705\|UniProtKB=F0ZVW9	Dictyostelium purpureum	O
THAPS\|EnsemblGenome=THAPSDRAFT_1936\|UniProtKB=B8BSC5	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_270374\|UniProtKB=B8BWV0	Thalassiosira pseudonana	O
CHLRE\|EnsemblGenome=CHLRE_10g422300v5\|UniProtKB=A8ICK6	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00007p00263960\|UniProtKB=W1P6M1	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_176G00240\|UniProtKB=A0A076E892	Zostera marina	O
MUSAM\|EnsemblGenome=Ma05_g16490\|UniProtKB=A0A804J556	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_007252mg\|UniProtKB=K3XZ93	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3010G072900\|UniProtKB=C5Z5Z4	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb278510\|UniProtKB=B4FS55	Zea mays	O
ORYSJ\|EnsemblGenome=Os06g0196300\|UniProtKB=P0C5D5	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g46622v3\|UniProtKB=A0A0Q3H912	Brachypodium distachyon	O
WHEAT\|EnsemblGenome=TraesKAR7D01G0084010\|UniProtKB=Q5S1S6	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_019065\|UniProtKB=A0A1U8B3L9	Nelumbo nucifera	O
SPIOL\|Gene=LOC110791943\|UniProtKB=A0A9R0IN22	Spinacia oleracea	O
SPIOL\|Gene=LOC110791944\|UniProtKB=A0A9R0JZS0	Spinacia oleracea	O
HELAN\|Gene_ORFName=HannXRQ_Chr12g0354281\|UniProtKB=A0A251T1F4	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C300125000\|UniProtKB=A0A9R1W8R3	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C600325810\|UniProtKB=A0A9R1VAF5	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C500279090\|UniProtKB=A0A9R1VGG4	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a013647mg\|UniProtKB=A0A022QGZ5	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_19321\|UniProtKB=A0A2G2Z1D2	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400013551\|UniProtKB=M1B225	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc07g042440.3\|UniProtKB=A0A3Q7H8S0	Solanum lycopersicum	O
TOBAC\|Gene=LOC107805477\|UniProtKB=A0A1S4B8A1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107778186\|UniProtKB=A0A1S3YPD8	Nicotiana tabacum	O
TOBAC\|Gene=LOC107777133\|UniProtKB=A0A1S3YKH3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107805800\|UniProtKB=A0A1S4B900	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi11g00038\|UniProtKB=D7TCA6	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_C00774\|UniProtKB=A0A059CN61	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00076600001\|UniProtKB=A0A078I0P7	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A06P23440.1\|UniProtKB=A0A078GTU7	Brassica napus	O
BRACM\|EnsemblGenome=Bra036365\|UniProtKB=M4F5K9	Brassica campestris	O
ARATH\|TAIR=locus=2092135\|UniProtKB=Q9LU86	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107932808\|UniProtKB=A0A1U8M4D2	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_037475\|UniProtKB=A0A061GKZ9	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g028030mg\|UniProtKB=A0A067GEE4	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_018G063300v3\|UniProtKB=A9PAI3	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_006G137500v3\|UniProtKB=B9HAD0	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_16G091900\|UniProtKB=A0A2C9UAC6	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0709690\|UniProtKB=B9RR55	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_13G113200\|UniProtKB=I1LY94	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_17G046500\|UniProtKB=I1MS47	Glycine max	O
MEDTR\|EnsemblGenome=MTR_4g124790\|UniProtKB=G7JS60	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr05_13070\|UniProtKB=A0A2I4DZZ0	Juglans regia	O
JUGRE\|EnsemblGenome=Jr01_24590\|UniProtKB=A0A2I4EN11	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_6G014770\|UniProtKB=A0A0A0KBU9	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_7G193400\|UniProtKB=M5WEV5	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_3G139200\|UniProtKB=M5VH39	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_7G193200\|UniProtKB=M5WAD1	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_422209\|UniProtKB=D8SHQ5	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_421285\|UniProtKB=D8SES0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_105456\|UniProtKB=D8RQ35	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c25_1840\|UniProtKB=A0A2K1IDG0	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c2_15400\|UniProtKB=A0A2K1L1M3	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c10_380\|UniProtKB=A0A2K1JX47	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0033s0151\|UniProtKB=A0A2R6X6P4	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000820140\|UniProtKB=A0A1Y1HY96	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000140230\|UniProtKB=A0A1Y1HJ19	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000140250\|UniProtKB=A0A1Y1HPH0	Klebsormidium nitens	O
NITMS\|EnsemblGenome=Nmar_1438\|UniProtKB=A9A3S2	Nitrosopumilus maritimus	O
NITMS\|EnsemblGenome=Nmar_0560\|UniProtKB=A9A243	Nitrosopumilus maritimus	O
SACS2\|EnsemblGenome=SSO2071\|UniProtKB=Q97WP9	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE0877\|UniProtKB=Q8ZYA3	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_4068\|UniProtKB=Q8TIS4	Methanosarcina acetivorans	O
HALSA\|EnsemblGenome=VNG_2311H\|UniProtKB=Q9HN00	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_1197G\|UniProtKB=Q9HQE6	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK1055\|UniProtKB=Q5JDZ1	Thermococcus kodakaraensis	O
CHLAA\|Gene_OrderedLocusName=Caur_0065\|UniProtKB=A9WBB2	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_2003\|UniProtKB=A9WEF6	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO2369\|UniProtKB=Q9KY21	Streptomyces coelicolor	LDO
STAA8\|EnsemblGenome=SAOUHSC_01999\|UniProtKB=Q2G280	Staphylococcus aureus	O
BACSU\|EnsemblGenome=BSU_08720\|UniProtKB=Q796Y8	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_0517\|UniProtKB=Q81I80	Bacillus cereus	O
DEIRA\|EnsemblGenome=DR_1208\|UniProtKB=Q9RV22	Deinococcus radiodurans	O
DEIRA\|EnsemblGenome=DR_0846\|UniProtKB=Q9RW23	Deinococcus radiodurans	O
GLOVI\|Gene=Q7NNA5_GLOVI\|UniProtKB=Q7NNA5	Gloeobacter violaceus	O
GLOVI\|Gene=Q7NI09_GLOVI\|UniProtKB=Q7NI09	Gloeobacter violaceus	O
GLOVI\|Gene=Q7NI08_GLOVI\|UniProtKB=Q7NI08	Gloeobacter violaceus	O
LEPIN\|EnsemblGenome=LB_117\|UniProtKB=Q8EXU1	Leptospira interrogans	O
LEPIN\|EnsemblGenome=LA_3442\|UniProtKB=Q8F0Q0	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_4611\|UniProtKB=Q89YX0	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB5869\|UniProtKB=Q7UR62	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB6761\|UniProtKB=Q7UPS0	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB5753\|UniProtKB=Q7URC5	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_458\|UniProtKB=O66763	Aquifex aeolicus	O
AQUAE\|EnsemblGenome=aq_495\|UniProtKB=O66785	Aquifex aeolicus	O
DICTD\|EnsemblGenome=Dtur_0405\|UniProtKB=B8E1S6	Dictyoglomus turgidum	O
HELPY\|EnsemblGenome=HP_0136\|UniProtKB=P55979	Helicobacter pylori	O
NEIMB\|EnsemblGenome=NMB0750\|UniProtKB=Q9K069	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU3447\|UniProtKB=Q746S1	Geobacter sulfurreducens	O
BRADU\|Gene=Q89M69_BRADU\|UniProtKB=Q89M69	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_0963\|UniProtKB=Q83CY8	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0254\|UniProtKB=P44411	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_1877\|UniProtKB=Q8EFT9	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_2160\|UniProtKB=Q9KQ44	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC1738\|UniProtKB=Q8P9V9	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA1008\|UniProtKB=Q9I4W5	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM2491\|UniProtKB=Q7CQ23	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO3064\|UniProtKB=Q0WCK4	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA16358\|UniProtKB=P0AE52	Escherichia coli	O