PANTHER Gene Information

Gene Symbol(s):

guaB1

Organism:

Mycobacterium tuberculosis

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Tree

Gene Name:

GMP reductase

Gene ID:

Rv1843c

Protein ID:

P9WKI3

Persistent Id:

PTN002455605

Alternate Ids:

395138613(GI)	guaB1(Symbol)
GUAB1(Synonym)	NZ_NVQJ01000013(refSeq)
CCP44609(EMBL-CDS)	AL123456(EMBL)
L0TAS0(AltAccession)	1.7.1.7 {ECO:0000269\|PubMed:35338694}(EC)
GUAB1_MYCTU(UniProtKB-ID)	885714(GeneID)
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PANTHER Classification

PANTHER Family:	GMP REDUCTASE (PTHR43170)
PANTHER Subfamily:	GMP REDUCTASE (PTHR43170:SF5)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	reductase

Pathway Categories:

De novo purine biosynthesis

IMP dehydrogenase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GMP reductase activity, oxidoreductase activity
GO BP Complete:	purine nucleotide biosynthetic process, IMP salvage, purine ribonucleoside salvage
GO CC Complete:	cytosol, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4376\|UniProtKB=P36959	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000017746.5\|UniProtKB=H2QSC0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000004162.3\|UniProtKB=G3QNH0	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000002936.4\|UniProtKB=G7MQS5	Macaca mulatta	O
MOUSE\|MGI=MGI=1913605\|UniProtKB=Q9DCZ1	Mus musculus	O
RAT\|RGD=70980\|UniProtKB=Q9Z244	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000015743.5\|UniProtKB=F6R1R5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000001064.5\|UniProtKB=A0A5G2QD15	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000022923.4\|UniProtKB=A0A9L0TC00	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000010501.5\|UniProtKB=M3WDD8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845024346.1\|UniProtKB=A0A8I3PQD8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000044598.1\|UniProtKB=A0A5F8H3S2	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000048791.1\|UniProtKB=A0A6I8P0Z9	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010011118.1\|UniProtKB=A0A8V0Y9S7	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000003844.4\|UniProtKB=G1KCB8	Anolis carolinensis	O
XENLA\|Gene=gmpr.L\|UniProtKB=A0A1L8FY48	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-982176\|UniProtKB=A9JRK1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000013044.2\|UniProtKB=H2MCQ8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050522-48\|UniProtKB=Q503G5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002927.1\|UniProtKB=W5M4Y6	lepisosteus oculatus	O
HUMAN\|HGNC=4377\|UniProtKB=Q9P2T1	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006207.6\|UniProtKB=A0A2J8QKH0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000042880.1\|UniProtKB=A0A2I2YNW8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000012455.4\|UniProtKB=F7FUX6	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1917903\|UniProtKB=Q99L27	Mus musculus	LDO
RAT\|RGD=628875\|UniProtKB=Q5FVP6	Rattus norvegicus	LDO
BOVIN\|Gene=GMPR2\|UniProtKB=Q32L93	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000002715.5\|UniProtKB=F1MCZ0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005016503.1\|UniProtKB=A0A4X1SRJ2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019714.4\|UniProtKB=A0A5F5PLT3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005592.6\|UniProtKB=A0A5F5Y1P1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845006349.1\|UniProtKB=A0A8I3N2R6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000003245.4\|UniProtKB=F6THE1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000044663.1\|UniProtKB=A0A6I8P7N5	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000004007.3\|UniProtKB=H9G8G6	Anolis carolinensis	LDO
XENLA\|Gene=LOC121394268\|UniProtKB=A0A8J1KTV5	Xenopus laevis	O
XENLA\|Gene=gmpr2.S\|UniProtKB=Q6GMC9	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1007066\|UniProtKB=Q5BL91	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007456.2\|UniProtKB=H2LTC9	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-1238\|UniProtKB=Q1RLT1	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000006633.3\|UniProtKB=F6U1G1	Ciona intestinalis	LDO
STRPU\|EnsemblGenome=LOC754448\|UniProtKB=A0A7M7N4X8	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00017984\|UniProtKB=O16294	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00041935\|UniProtKB=A8WIY8	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00273214\|UniProtKB=A0A454XQ61	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00113325\|UniProtKB=A0A2A6BG13	Pristionchus pacificus	LDO
TRICA\|EnsemblGenome=TC009423\|UniProtKB=D6WQX7	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_210496\|UniProtKB=E9GCV2	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW019974\|UniProtKB=B7PTS0	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG186261\|UniProtKB=T1FNV9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG180856\|UniProtKB=T1FGC2	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g227565\|UniProtKB=A7SWU4	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG63276\|UniProtKB=B3RVD3	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_16151\|UniProtKB=A9UWE3	Monosiga brevicollis	LDO
PHYRM\|Gene=H3G8N5_PHYRM\|UniProtKB=H3G8N5	Phytophthora ramorum	LDO
STRCO\|Gene_OrderedLocusName=SCO1461\|UniProtKB=Q9L0Z8	Streptomyces coelicolor	LDO
STRR6\|EnsemblGenome=spr1128\|UniProtKB=Q8DPJ7	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_01330\|UniProtKB=Q2FYU4	Staphylococcus aureus	LDO
BACSU\|EnsemblGenome=BSU_32130\|UniProtKB=O05269	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_5452\|UniProtKB=Q814I1	Bacillus cereus	LDO
HELPY\|EnsemblGenome=HP_0854\|UniProtKB=O25525	Helicobacter pylori	LDO