PANTHER Gene Information

Gene Symbol(s):

hemL

Organism:

Mycobacterium tuberculosis

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Gene Name:

Glutamate-1-semialdehyde 2,1-aminomutase

Gene ID:

Rv0524

Protein ID:

P9WMN9

Persistent Id:

PTN002463953

Alternate Ids:

NZ_NVQJ01000068(refSeq)	5.4.3.8(EC)
GSA_MYCTU(UniProtKB-ID)	O06390(AltAccession)
Glutamate-1-semialdehyde aminotransferase(Synonym)	887349(GeneID)
AL123456(EMBL)	hemL(Symbol)
395137227(GI)	CCP43261(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (PTHR43713)
PANTHER Subfamily:	GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE 1, CHLOROPLASTIC-RELATED (PTHR43713:SF3)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	mutase

Pathway Categories:

Heme biosynthesis

Glutamate-1-semialdehyde 2,1-aminomutase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	pyridoxal phosphate binding, transaminase activity, glutamate-1-semialdehyde 2,1-aminomutase activity, isomerase activity
GO BP Complete:	porphyrin-containing compound biosynthetic process, tetrapyrrole biosynthetic process, protoporphyrinogen IX biosynthetic process
GO CC Complete:	cytoplasm, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
BRAFL\|Gene=LOC118423637\|UniProtKB=A0A9J7LRG6	Branchiostoma floridae	LDO
EMENI\|EnsemblGenome=ANIA_10913\|UniProtKB=C8VD01	Emericella nidulans	LDO
NEUCR\|EnsemblGenome=NCU09304\|UniProtKB=Q7S1H7	Neurospora crassa	LDO
PHANO\|EnsemblGenome=SNOG_13513\|UniProtKB=Q0U401	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_00213\|UniProtKB=Q0V701	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC417.11c\|UniProtKB=O94492	Schizosaccharomyces pombe	LDO
CRYNJ\|EnsemblGenome=CNF01050\|UniProtKB=Q5KFP5	Cryptococcus neoformans	LDO
THAPS\|EnsemblGenome=THAPS_6818\|UniProtKB=B5YMK2	Thalassiosira pseudonana	LDO
NITMS\|EnsemblGenome=Nmar_0148\|UniProtKB=A9A1S7	Nitrosopumilus maritimus	O
NITMS\|EnsemblGenome=Nmar_1017\|UniProtKB=A9A3I1	Nitrosopumilus maritimus	O
NITMS\|EnsemblGenome=Nmar_0490\|UniProtKB=A9A1A0	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_0329\|UniProtKB=B1L3Q8	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO0182\|UniProtKB=Q980U5	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE0594\|UniProtKB=Q8ZYW1	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_0581\|UniProtKB=Q8TT57	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_0603\|UniProtKB=Q58020	Methanocaldococcus jannaschii	LDO
HALSA\|EnsemblGenome=VNG_2326G\|UniProtKB=Q9HMY8	Halobacterium salinarum	LDO
CHLAA\|EnsemblGenome=Caur_3802\|UniProtKB=A9WCL8	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_2598\|UniProtKB=A9WIS7	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO0401\|UniProtKB=Q9RJI7	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4469\|UniProtKB=Q9F2S0	Streptomyces coelicolor	LDO
STAA8\|EnsemblGenome=SAOUHSC_02000\|UniProtKB=Q2G283	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAC99763\|UniProtKB=Q8Y6J9	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_08710\|UniProtKB=P71084	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_0512\|UniProtKB=Q81I85	Bacillus cereus	O
STAA8\|EnsemblGenome=SAOUHSC_01771\|UniProtKB=Q2FXR4	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAC99631\|UniProtKB=Q8Y6X8	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_28120\|UniProtKB=P30949	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_4468\|UniProtKB=Q817R3	Bacillus cereus	LDO
DEIRA\|EnsemblGenome=DR_0555\|UniProtKB=Q9RWW0	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC88012\|UniProtKB=Q7NPI4	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA10185\|UniProtKB=Q55665	Synechocystis	LDO
LEPIN\|EnsemblGenome=LB_013\|UniProtKB=Q8EY44	Leptospira interrogans	LDO
CHLTR\|EnsemblGenome=CT_210\|UniProtKB=O84212	Chlamydia trachomatis	LDO
RHOBA\|EnsemblGenome=RB6831\|UniProtKB=Q7UPM9	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_816\|UniProtKB=O66998	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0147\|UniProtKB=B5YHH6	Thermodesulfovibrio yellowstonii	LDO
FUSNN\|EnsemblGenome=FN0540\|UniProtKB=Q8RFY7	Fusobacterium nucleatum	LDO
HELPY\|EnsemblGenome=HP_0306\|UniProtKB=P56115	Helicobacter pylori	LDO
NEIMB\|EnsemblGenome=NMB1864\|UniProtKB=Q9JXW0	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU0337\|UniProtKB=Q74GA9	Geobacter sulfurreducens	LDO
BRADU\|Gene=Q89FR7_BRADU\|UniProtKB=Q89FR7	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89PD0_BRADU\|UniProtKB=Q89PD0	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_1882\|UniProtKB=Q83AK3	Coxiella burnetii	LDO
SHEON\|Gene_OrderedLocusName=SO_1300\|UniProtKB=Q8EHC8	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_0626\|UniProtKB=Q9KU97	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC3272\|UniProtKB=Q8P5R4	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA4088\|UniProtKB=Q9HWU0	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA5523\|UniProtKB=Q9HT50	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA3977\|UniProtKB=P48247	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM0202\|UniProtKB=P0CL07	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_0296\|UniProtKB=Q8ZBL9	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAB96731\|UniProtKB=P23893	Escherichia coli	LDO