PANTHER Gene Information

Gene Symbol(s):

Rv0805

Organism:

Mycobacterium tuberculosis

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Gene Name:

cAMP_cGMP dual specificity phosphodiesterase Rv0805

Gene ID:

Rv0805

Protein ID:

P9WP65

Persistent Id:

PTN002293167

Alternate Ids:

885326(GeneID)	L0T7J7(AltAccession)
CNPD3_MYCTU(UniProtKB-ID)	3',5'-cyclic-nucleotide phosphodiesterase {ECO:0000303\|PubMed:16313172}(Synonym)
AL123456(EMBL)	WP_003404120(refSeq)
260100110(GI)	CCP43553(EMBL-CDS)
3.1.4.16 {ECO:0000269\|PubMed:18757371, ECO:0000269\|PubMed:19801656, ECO:0000269\|PubMed:24970891}(EC)
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PANTHER Classification

PANTHER Family:	METALLOPHOSPHOESTERASE (PTHR12905)
PANTHER Subfamily:	CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN (PTHR12905:SF0)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	esterase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	nucleotide binding, protein binding, ferric iron binding, iron ion binding, metal ion binding, 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity, manganese ion binding, 3',5'-cyclic-GMP phosphodiesterase activity, phosphate ion binding, cyclic-nucleotide phosphodiesterase activity, 3',5'-cyclic-AMP phosphodiesterase activity, hydrolase activity
GO BP Complete:	cell wall modification
GO CC Complete:	cytoplasm, peptidoglycan-based cell wall, extracellular region, plasma membrane, cell envelope

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=1180\|UniProtKB=Q15777	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000003466.6\|UniProtKB=A0A2I3S9A3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010368.3\|UniProtKB=G3R4B9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000017592.4\|UniProtKB=F6WJ08	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1924265\|UniProtKB=Q9CZJ0	Mus musculus	LDO
RAT\|RGD=735060\|UniProtKB=B1WBP0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020956.6\|UniProtKB=A5PJ77	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000013327.6\|UniProtKB=F1SGP0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019460.3\|UniProtKB=A0A9L0SBP1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001706.5\|UniProtKB=M3VX47	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029423.1\|UniProtKB=A0A8I3QJJ0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000009548.4\|UniProtKB=F7BK04	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000028269.2\|UniProtKB=K7EFC2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010022622.1\|UniProtKB=E1BXB8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000022571.3\|UniProtKB=G1KW46	Anolis carolinensis	LDO
XENLA\|Gene=mpped2.L\|UniProtKB=A0A1L8GJ15	Xenopus laevis	O
XENLA\|Gene=mpped2.S\|UniProtKB=Q6GLV7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1016332\|UniProtKB=A0A803KJK0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000000727.2\|UniProtKB=H2L538	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-8903\|UniProtKB=Q7ZUB6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050417-241\|UniProtKB=Q567D4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004698.1\|UniProtKB=W5MB83	lepisosteus oculatus	LDO
HUMAN\|HGNC=1306\|UniProtKB=O15442	Homo sapiens	O
GORGO\|Ensembl=ENSGGOG00000043344.1\|UniProtKB=A0A2I2YM18	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000022590.4\|UniProtKB=H9EPG3	Macaca mulatta	O
MOUSE\|MGI=MGI=106316\|UniProtKB=Q91ZG2	Mus musculus	O
RAT\|RGD=1308244\|UniProtKB=D4A120	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000053619.1\|UniProtKB=A0A3Q1M3T4	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000038685.3\|UniProtKB=I3LHN0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000020812.3\|UniProtKB=A0A9L0RIR8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000036862.3\|UniProtKB=M3X3A7	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845013653.1\|UniProtKB=A0A8I3NTB0	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000008782.2\|UniProtKB=F6WJR2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010011998.1\|UniProtKB=A0A8V0Y777	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000029062.2\|UniProtKB=A0A803SMV2	Anolis carolinensis	O
XENLA\|Gene=LOC108710556\|UniProtKB=A0A1L8GW38	Xenopus laevis	O
XENLA\|Gene=mpped1.S\|UniProtKB=A0A1L8GQD0	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000043661\|UniProtKB=A0A803K3V5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000011713.2\|UniProtKB=H2M871	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-111104-1\|UniProtKB=F1QUV1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015072.1\|UniProtKB=W5ND41	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000000706.3\|UniProtKB=F6QLG8	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118406669\|UniProtKB=A0A9J7HRN6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC577091\|UniProtKB=A0A7M7P634	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00016101\|UniProtKB=Q18161	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038443\|UniProtKB=A8XV05	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00280235\|UniProtKB=A0A2A6BRJ8	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00019479\|UniProtKB=Q21268	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00032458\|UniProtKB=A8XDA2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00101898\|UniProtKB=A0A8R1UCB6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00112826\|UniProtKB=A0A2A6CPG4	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00091225\|UniProtKB=A0A454XWP6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00091459\|UniProtKB=A0A8R1Y5R6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00011579\|UniProtKB=Q22306	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG03200\|UniProtKB=A8WSK2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00112166\|UniProtKB=A0A2A6B8M8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0036028\|UniProtKB=Q9VT29	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004891\|UniProtKB=Q7Q990	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC032520\|UniProtKB=A0A139WKX5	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC003443\|UniProtKB=D6WGJ9	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW017004\|UniProtKB=B7PAE2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG168494\|UniProtKB=T1F0M8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g234821\|UniProtKB=A7S2M8	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG51679\|UniProtKB=B3RKH2	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_30056\|UniProtKB=A9VCW4	Monosiga brevicollis	LDO
EMENI\|EnsemblGenome=ANIA_04139\|UniProtKB=Q5B5P1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G17260\|UniProtKB=Q4WZE3	Neosartorya fumigata	O
EMENI\|EnsemblGenome=ANIA_02476\|UniProtKB=Q5BAF4	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G03130\|UniProtKB=Q4WA02	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU06375\|UniProtKB=Q7S9T1	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_13097\|UniProtKB=A7F669	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_12627\|UniProtKB=Q0U6I7	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_02087\|UniProtKB=Q0V1M7	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_10532\|UniProtKB=C8V4C8	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G06000\|UniProtKB=Q4WJH0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU04147\|UniProtKB=V5IND1	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_07379\|UniProtKB=A7EPY0	Sclerotinia sclerotiorum	O
PHANO\|Gene_ORFName=SNOG_11867\|UniProtKB=Q0U8P7	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_00464\|UniProtKB=C8VT65	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G04330\|UniProtKB=Q4WJY9	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU06689\|UniProtKB=Q7S7M9	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU01093\|UniProtKB=Q1K882	Neurospora crassa	LDO
NEUCR\|EnsemblGenome=NCU08795\|UniProtKB=Q7RWW9	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_01305\|UniProtKB=A7E7M7	Sclerotinia sclerotiorum	LDO
PHANO\|Gene_ORFName=SNOG_00826\|UniProtKB=Q0V588	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_07557\|UniProtKB=Q0UL07	Phaeosphaeria nodorum	LDO
USTMA\|EnsemblGenome=UMAG_11726\|UniProtKB=A0A0D1DZF5	Ustilago maydis	LDO
ENTH1\|EnsemblGenome=CL6EHI_197060\|UniProtKB=C4LVC3	Entamoeba histolytica	LDO
ENTH1\|EnsemblGenome=CL6EHI_152640\|UniProtKB=C4LSU9	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_008800\|UniProtKB=C4M0P4	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_139350\|UniProtKB=C4M6X4	Entamoeba histolytica	O
LEIMA\|EnsemblGenome=LMJF_36_2670\|UniProtKB=Q4Q1F4	Leishmania major	LDO
PARTE\|EnsemblGenome=GSPATT00003225001\|UniProtKB=A0DYZ0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037414001\|UniProtKB=A0CCW2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012093001\|UniProtKB=A0D0H4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00001382001\|UniProtKB=A0CWL2	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00002659001\|UniProtKB=A0DQE2	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_21245\|UniProtKB=B8BU60	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GL40_PHYRM\|UniProtKB=H3GL40	Phytophthora ramorum	LDO
PHYRM\|Gene=H3HB28_PHYRM\|UniProtKB=H3HB28	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_12g525550v5\|UniProtKB=A0A2K3D4E5	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_09g388171v5\|UniProtKB=A8J139	Chlamydomonas reinhardtii	LDO
KLENI\|Gene_ORFName=KFL_002760100\|UniProtKB=A0A1Y1I6S0	Klebsormidium nitens	LDO
KORCO\|EnsemblGenome=Kcr_1601\|UniProtKB=B1L7B7	Korarchaeum cryptofilum	LDO
PYRAE\|EnsemblGenome=PAE1087\|UniProtKB=Q8ZXU7	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_1449\|UniProtKB=Q8TQU0	Methanosarcina acetivorans	LDO
CHLAA\|EnsemblGenome=Caur_3886\|UniProtKB=A9WDE4	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO2130\|UniProtKB=Q9X7Y9	Streptomyces coelicolor	LDO
LEPIN\|EnsemblGenome=LA_3941\|UniProtKB=Q8EZB3	Leptospira interrogans	LDO
RHOBA\|EnsemblGenome=RB5332\|UniProtKB=Q7US08	Rhodopirellula baltica	LDO
DICTD\|EnsemblGenome=Dtur_1270\|UniProtKB=B8E0A3	Dictyoglomus turgidum	LDO
BRADU\|Gene=Q89W37_BRADU\|UniProtKB=Q89W37	Bradyrhizobium diazoefficiens	LDO
HAEIN\|EnsemblGenome=HI_0399\|UniProtKB=P44685	Haemophilus influenzae	LDO
VIBCH\|EnsemblGenome=VC_2433\|UniProtKB=Q9KPD7	Vibrio cholerae	LDO
SALTY\|EnsemblGenome=STM3183\|UniProtKB=Q8ZLZ6	Salmonella typhimurium	LDO
YERPE\|Gene_OrderedLocusName=YPO0666\|UniProtKB=A0A2S9PLV7	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAE77088\|UniProtKB=P0AEW4	Escherichia coli	LDO