PANTHER Gene Information

Gene Symbol(s):

argH

Organism:

Mycobacterium tuberculosis

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Gene Name:

Argininosuccinate lyase

Gene ID:

Rv1659

Protein ID:

P9WPY7

Persistent Id:

PTN002466105

Alternate Ids:

ARLY_MYCTU(UniProtKB-ID)	885365(GeneID)
NC_000962(refSeq)	L0TA28(AltAccession)
4.3.2.1 {ECO:0000255\|HAMAP-Rule:MF_00006}(EC)	444895168(GI)
AL123456(EMBL)	CCP44424(EMBL-CDS)
Arginosuccinase {ECO:0000255\|HAMAP-Rule:MF_00006}(Synonym)	argH{ECO:0000255\|HAMAP-Rule:MF_00006}(Symbol)
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PANTHER Classification

PANTHER Family:	ARGININOSUCCINATE LYASE (PTHR43814)
PANTHER Subfamily:	ARGININOSUCCINATE LYASE (PTHR43814:SF1)
PANTHER GO-slim Molecular Function:	lyase activity
PANTHER GO-slim Biological Process:	L-amino acid biosynthetic process arginine metabolic process proteinogenic amino acid biosynthetic process
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	lyase

Pathway Categories:

Arginine biosynthesis

argininosuccinate lyase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	lyase activity, argininosuccinate lyase activity
GO BP Complete:	L-arginine biosynthetic process, arginine biosynthetic process via ornithine
GO CC Complete:	cytoplasm, peptidoglycan-based cell wall, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=746\|UniProtKB=P04424	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000019245.6\|UniProtKB=H2RBX6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007222.3\|UniProtKB=A0A2I2YTY7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011871.4\|UniProtKB=H9FUL9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=88084\|UniProtKB=Q91YI0	Mus musculus	LDO
RAT\|RGD=619974\|UniProtKB=P20673	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015314\|UniProtKB=Q3SZJ0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000007738.5\|UniProtKB=F1RJH8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000012730.4\|UniProtKB=A0A9L0RJP7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006929.6\|UniProtKB=A0A2I2UJE0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013432.1\|UniProtKB=A0A8I3P007	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000027474.2\|UniProtKB=A0A5F8G5P7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000020360.3\|UniProtKB=F7C9Q8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00015026068\|UniProtKB=P02521	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010029665.1\|UniProtKB=A0A1L1RIY4	Gallus gallus	LDO
CHICK\|Gene=ASL2\|UniProtKB=P05083	Gallus gallus	LDO
XENLA\|Gene=asl.L\|UniProtKB=A0A1L8HG59	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-987476\|UniProtKB=A9JTM9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002500.2\|UniProtKB=H2LB38	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1152\|UniProtKB=F1RA91	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005320.1\|UniProtKB=W5MDF5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006327.3\|UniProtKB=F6PYH8	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118426332\|UniProtKB=A0A9J7M039	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC574725\|UniProtKB=A0A7M7GIW1	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0032076\|UniProtKB=Q9VLG9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP008141\|UniProtKB=A0A1S4GY36	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC008532\|UniProtKB=D7EI90	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_304871\|UniProtKB=E9GME3	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG103632\|UniProtKB=T1EDG7	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g172052\|UniProtKB=A7SM51	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG30108\|UniProtKB=B3S676	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_11183\|UniProtKB=A9V8F9	Monosiga brevicollis	LDO
YEAST\|SGD=S000001060\|UniProtKB=P04076	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AEL019W\|UniProtKB=Q757L9	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000190527\|UniProtKB=Q59R31	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D26367g\|UniProtKB=Q6C7P9	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_02914\|UniProtKB=C8VJ67	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G07790\|UniProtKB=Q4WX07	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08162\|UniProtKB=Q7S4I8	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_03962\|UniProtKB=A7EF71	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_15639\|UniProtKB=Q0TY06	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC1773.14\|UniProtKB=P40369	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPBC1539.03c\|UniProtKB=P50514	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01461\|UniProtKB=B6JY01	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC04420\|UniProtKB=Q5KK33	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_04497\|UniProtKB=A0A0D1C0F3	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_04819\|UniProtKB=E3K306	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_34150\|UniProtKB=F4NS11	Batrachochytrium dendrobatidis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_29075\|UniProtKB=B8C6D4	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G8W5_PHYRM\|UniProtKB=H3G8W5	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_01g021251v5\|UniProtKB=A0A2K3E625	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00033p00236040\|UniProtKB=U5CW82	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_179G00190\|UniProtKB=A0A0K9PRA1	Zostera marina	LDO
ZOSMR\|Gene_ORFName=ZOSMA_20G00170\|UniProtKB=A0A0K9PMT6	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g04910\|UniProtKB=A0A804L4C1	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_039472mg\|UniProtKB=K4AKP8	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G397100\|UniProtKB=A0A1B6QNP9	Sorghum bicolor	O
BRADI\|EnsemblGenome=BRADI_1g64603v3\|UniProtKB=A0A2K2DTE7	Brachypodium distachyon	O
SETIT\|EnsemblGenome=SETIT_021759mg\|UniProtKB=K3Z5E1	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_035209mg\|UniProtKB=K4A8K3	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G397000\|UniProtKB=C5WMI0	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb396370\|UniProtKB=B4FAV4	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0305500\|UniProtKB=A0A024FLK4	Oryza sativa	O
WHEAT\|EnsemblGenome=TraesCS4B02G185000\|UniProtKB=A0A3B6IRJ2	Triticum aestivum	O
ORYSJ\|Gene_OrderedLocusName=Os03g0824700\|UniProtKB=Q94GD6	Oryza sativa	O
ORYSJ\|Gene_OrderedLocusName=Os03g0824900\|UniProtKB=Q94GD8	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g64597v3\|UniProtKB=I1H694	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0495980\|UniProtKB=A0A8I6YAQ8	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5D02G307100\|UniProtKB=A0A3B6MUY4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G299700\|UniProtKB=A0A3B6LNU2	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0382620\|UniProtKB=M0YLV9	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS4A02G119700\|UniProtKB=A0A3B6HQN3	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS4D02G186300\|UniProtKB=A0A3B6JL49	Triticum aestivum	LDO
NELNU\|Gene=LOC104595496\|UniProtKB=A0A1U8A0H6	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110796517\|UniProtKB=A0A9R0IZH9	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0706071\|UniProtKB=A0A251S9Q4	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900486970\|UniProtKB=A0A9R1UFG9	Lactuca sativa	LDO
LACSA\|Gene_ORFName=LSAT_V11C600338080\|UniProtKB=A0A9R1V4H1	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a006916mg\|UniProtKB=A0A022QM71	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_12801\|UniProtKB=A0A2G2ZQV9	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400009343\|UniProtKB=M1AJK6	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc04g076320.3\|UniProtKB=A0A3Q7H0R9	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107802171\|UniProtKB=A0A1S4AWW1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107783840\|UniProtKB=A0A1S3Z7A0	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi18g00523\|UniProtKB=E0CRW7	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F02151\|UniProtKB=A0A059BS98	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00079160001\|UniProtKB=A0A078FNN2	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra009004\|UniProtKB=M4CXQ7	Brassica campestris	LDO
ARATH\|TAIR=locus=2183825\|UniProtKB=Q9LEU8	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107922428\|UniProtKB=A0A1U8KZW5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107917934\|UniProtKB=A0A1U8KK70	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_034512\|UniProtKB=A0A061FEW1	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g010020mg\|UniProtKB=A0A067GNB8	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_002G106200v3\|UniProtKB=A0A2K2BGU9	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_18G058500\|UniProtKB=A0A2C9U2G5	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1039580\|UniProtKB=B9RJX6	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_06G096700\|UniProtKB=I1K9R1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_04G094600\|UniProtKB=I1JV68	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_3g100220\|UniProtKB=G7J530	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr11_22000\|UniProtKB=A0A2I4G1M3	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_2G370510\|UniProtKB=A0A0A0LPM3	Cucumis sativus	LDO
CUCSA\|EnsemblGenome=Csa_3G891650\|UniProtKB=A0A0A0LE21	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G532200\|UniProtKB=M5XXR6	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_232328\|UniProtKB=D8RTQ6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_132338\|UniProtKB=D8T5F5	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c18_13220\|UniProtKB=A0A2K1J0X5	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0005s0193\|UniProtKB=A0A2R6XR34	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000380130\|UniProtKB=A0A1Y1HME1	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0263\|UniProtKB=A9A331	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_0163\|UniProtKB=B1L394	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO0639\|UniProtKB=Q9UX32	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE2887\|UniProtKB=Q8ZU95	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_1318\|UniProtKB=Q8TR65	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_0791\|UniProtKB=Q58201	Methanocaldococcus jannaschii	LDO
HALSA\|EnsemblGenome=VNG_2436G\|UniProtKB=Q9HMQ3	Halobacterium salinarum	LDO
STRCO\|Gene_OrderedLocusName=SCO1570\|UniProtKB=Q9L1B1	Streptomyces coelicolor	LDO
CLOBH\|Gene_OrderedLocusName=CBO2669\|UniProtKB=A5I5A3	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr0103\|UniProtKB=Q8DRI4	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_00898\|UniProtKB=Q2FZU2	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAD00169\|UniProtKB=Q8Y5H1	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_29440\|UniProtKB=O34858	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_3550\|UniProtKB=Q81AL3	Bacillus cereus	O
BACCR\|EnsemblGenome=BC_4629\|UniProtKB=Q817C7	Bacillus cereus	LDO
DEIRA\|EnsemblGenome=DR_0678\|UniProtKB=Q9RWJ0	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC88992\|UniProtKB=Q7NLS0	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA17284\|UniProtKB=P73257	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_2076\|UniProtKB=Q8F4G5	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_3733\|UniProtKB=Q8A1D3	Bacteroides thetaiotaomicron	LDO
RHOBA\|EnsemblGenome=RB10834\|UniProtKB=Q7UK64	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_1372\|UniProtKB=O67383	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0553\|UniProtKB=B5YJI1	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_1781\|UniProtKB=B8E0N3	Dictyoglomus turgidum	LDO
NEIMB\|EnsemblGenome=NMB0637\|UniProtKB=Q9K0G8	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU0156\|UniProtKB=Q74GT9	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC46646\|UniProtKB=P59613	Bradyrhizobium diazoefficiens	LDO
HAEIN\|EnsemblGenome=HI_0811\|UniProtKB=P44314	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_0279\|UniProtKB=Q8EK27	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_2641\|UniProtKB=Q9KNT9	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC2242\|UniProtKB=Q8P8J9	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA5263\|UniProtKB=P50987	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM4123\|UniProtKB=Q8ZKL6	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_3125\|UniProtKB=Q8ZA88	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAE77351\|UniProtKB=P11447	Escherichia coli	LDO