PANTHER Gene Information

Gene Symbol(s):

Khk

Organism:

Rattus norvegicus

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Gene Name:

Ketohexokinase

Gene ID:

2966

Protein ID:

Q02974

Persistent Id:

PTN000061873

Alternate Ids:

1845171(GI)	P97550(AltAccession)
X63658(EMBL)	2.7.1.3 {ECO:0000269\|PubMed:8471037}(EC)
Hepatic fructokinase(Synonym)	KHK_RAT(UniProtKB-ID)
2966(RGD)	25659(GeneID)
CHEMBL4105923(ChEMBL)	AAH78752(EMBL-CDS)
Khk{ECO:0000312\|RGD:2966}(Symbol)
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PANTHER Classification

PANTHER Family:	HEXOKINASE FAMILY MEMBER (PTHR43085)
PANTHER Subfamily:	KETOHEXOKINASE (PTHR43085:SF55)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	carbohydrate kinase

Pathway Categories:

Fructose galactose metabolism

Ketohexokinase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP binding, identical protein binding, fructose binding, protein homodimerization activity, ketohexokinase activity
GO BP Complete:	response to glucose, response to zinc ion, response to insulin, response to fructose, carbohydrate catabolic process, fructose metabolic process, fructose catabolic process, regulation of glycogen metabolic process, carbohydrate phosphorylation, response to sucrose, fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
GO CC Complete:	nucleus, cytoplasm, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Fructose metabolism, Metabolism, Fructose catabolism, Metabolism of carbohydrates

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6315\|UniProtKB=P50053	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000011746.5\|UniProtKB=H2QHL3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002595.3\|UniProtKB=A0A2I2ZK23	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=1096353\|UniProtKB=P97328	Mus musculus	LDO
HORSE\|Ensembl=ENSECAG00000025017.4\|UniProtKB=A0A3Q2IAG0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000009886.5\|UniProtKB=A0A2I2U2F8	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000015726.3\|UniProtKB=A0A5F8GPE3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000000509.3\|UniProtKB=F7CVJ4	Ornithorhynchus anatinus	LDO
ORYLA\|Ensembl=ENSORLG00000013091.2\|UniProtKB=H2MCX1	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000015943.1\|UniProtKB=W5NG72	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004329.3\|UniProtKB=F7BN93	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_219293\|UniProtKB=C3Y1K0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409679\|UniProtKB=A0A9J7KMJ7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC588197\|UniProtKB=A0A7M7RGI9	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0036161\|UniProtKB=Q8T4I0	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036160\|UniProtKB=Q9VTI3	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036941\|UniProtKB=Q9VW82	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036942\|UniProtKB=Q9VW84	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002483\|UniProtKB=Q5TTS3	Anopheles gambiae	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_213561\|UniProtKB=E9GTM4	Daphnia pulex	LDO
TRIAD\|EnsemblGenome=TriadG58015\|UniProtKB=B3S2G3	Trichoplax adhaerens	LDO
EMENI\|EnsemblGenome=ANIA_10054\|UniProtKB=C8VTZ4	Emericella nidulans	LDO
NEUCR\|EnsemblGenome=NCU03742\|UniProtKB=V5IMP9	Neurospora crassa	LDO
DICDI\|dictyBase=DDB_G0292440\|UniProtKB=Q54D80	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_39975\|UniProtKB=F0ZXC3	Dictyostelium purpureum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_156747\|UniProtKB=F0ZXC0	Dictyostelium purpureum	LDO
PYRAE\|EnsemblGenome=PAE3318\|UniProtKB=Q8ZTC9	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_3267\|UniProtKB=Q8TKX6	Methanosarcina acetivorans	LDO
THEMA\|EnsemblGenome=TM_0415\|UniProtKB=Q9WYP6	Thermotoga maritima	O
BACTN\|EnsemblGenome=BT_3576\|UniProtKB=Q8A1T2	Bacteroides thetaiotaomicron	O
STRCO\|Gene_OrderedLocusName=SCO6978\|UniProtKB=Q9KZH4	Streptomyces coelicolor	O
LISMO\|EnsemblGenome=CAC98464\|UniProtKB=Q8Y9Y2	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_39740\|UniProtKB=P42414	Bacillus subtilis	O
CHLAA\|EnsemblGenome=Caur_3023\|UniProtKB=A9WGQ6	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO2158\|UniProtKB=Q9X816	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv2202c\|UniProtKB=P9WID5	Mycobacterium tuberculosis	O
CHLAA\|EnsemblGenome=Caur_1424\|UniProtKB=A9WA93	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_2881\|UniProtKB=A9WF96	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO1957\|UniProtKB=Q9Z508	Streptomyces coelicolor	O
CLOBH\|Gene_OrderedLocusName=CBO1168\|UniProtKB=A5I108	Clostridium botulinum	O
CLOBH\|Gene_OrderedLocusName=CBO1769\|UniProtKB=A5I2P1	Clostridium botulinum	O
STAA8\|EnsemblGenome=SAOUHSC_00291\|UniProtKB=Q2G164	Staphylococcus aureus	O
STAA8\|EnsemblGenome=SAOUHSC_02267\|UniProtKB=Q2FWM2	Staphylococcus aureus	O
BACSU\|EnsemblGenome=BSU_06170\|UniProtKB=O34768	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_0773\|UniProtKB=Q81HN1	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_0296\|UniProtKB=Q9WYD2	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_0728\|UniProtKB=Q9RWE1	Deinococcus radiodurans	O
GLOVI\|Gene=Q7NNA9_GLOVI\|UniProtKB=Q7NNA9	Gloeobacter violaceus	O
SYNY3\|Gene=cscK\|UniProtKB=P73521	Synechocystis	O
RHOBA\|EnsemblGenome=RB5198\|UniProtKB=Q7UGI5	Rhodopirellula baltica	O
SALTY\|EnsemblGenome=STM3251\|UniProtKB=Q8ZLV6	Salmonella typhimurium	O
DICTD\|EnsemblGenome=Dtur_0388\|UniProtKB=B8DZ66	Dictyoglomus turgidum	O
DICTD\|EnsemblGenome=Dtur_0795\|UniProtKB=B8DZZ3	Dictyoglomus turgidum	O
BRADU\|Gene=kdgK\|UniProtKB=Q89NC0	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_1223\|UniProtKB=Q83CA5	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0049\|UniProtKB=P44482	Haemophilus influenzae	O
SALTY\|EnsemblGenome=STM3612\|UniProtKB=Q8ZLC0	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO3990\|UniProtKB=A0A3N4B6X2	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA15563\|UniProtKB=P77493	Escherichia coli	O
ECOLI\|EnsemblGenome=BAE77768\|UniProtKB=P37647	Escherichia coli	O
SHEON\|Gene_OrderedLocusName=SO_2020\|UniProtKB=Q8EFF3	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_A0801\|UniProtKB=Q9KLE5	Vibrio cholerae	O
VIBCH\|EnsemblGenome=VC_1129\|UniProtKB=Q9KSX7	Vibrio cholerae	O
SALTY\|EnsemblGenome=STM0491\|UniProtKB=Q8ZRA0	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO3095\|UniProtKB=A0A3N4B1Y6	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76256\|UniProtKB=P0AEW6	Escherichia coli	O
SHEON\|Gene_OrderedLocusName=SO_4458\|UniProtKB=Q8E935	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_A0656\|UniProtKB=Q9KLT5	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC1509\|UniProtKB=Q8PAH4	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA2344\|UniProtKB=Q9I1D4	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM3600\|UniProtKB=Q8ZLD1	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAE77917\|UniProtKB=P45543	Escherichia coli	O
SALTY\|EnsemblGenome=STM4066\|UniProtKB=Q8ZKR2	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAA15968\|UniProtKB=P76419	Escherichia coli	O