PANTHER Gene Information

Gene Symbol(s):

PKH3

Organism:

Saccharomyces cerevisiae

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Gene Name:

Serine_threonine-protein kinase PKH3

Gene ID:

S000002874

Protein ID:

Q03306

Persistent Id:

PTN000682543

Alternate Ids:

6320674(GI)	S000002874(SGD)
852077(GeneID)	YDR466W(Ensembl)
PKH3(Synonym)	YDR466W(Ensembl_PRO)
YDR466W_mRNA(Ensembl_TRS)	PKH3(Symbol)
AAB64902(EMBL-CDS)	U33050(EMBL)
D6VT91(AltAccession)	PKH3_YEAST(UniProtKB-ID)
YEAST:G3O-29994-MON(BioCyc)	NM_001180774(refSeq)
2.7.11.1(EC)
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PANTHER Classification

PANTHER Family:	SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily:	SERINE_THREONINE-PROTEIN KINASE PKH3 (PTHR24356:SF405)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	peptidyl-serine phosphorylation intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

Insulin/IGF pathway-protein kinase B signaling cascade

3-phosphoinositide-dependent protein kinase 1 and 2

PDGF signaling pathway

3-phosphoinositide-dependent protein kinase 1 and 2

p53 pathway

3-phosphoinositide-dependent protein kinase 1 and 2

p53 pathway feedback loops 2

3-phosphoinositide-dependent protein kinase 1 and 2

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	histone H3S10 kinase activity, histone H2BS14 kinase activity, histone H2AS1 kinase activity, protein kinase activity, eukaryotic translation initiation factor 2alpha kinase activity, protein serine/threonine kinase activity, 3-phosphoinositide-dependent protein kinase activity, ribosomal protein S6 kinase activity, DNA-dependent protein kinase activity, ATP binding, histone H2AT120 kinase activity, AMP-activated protein kinase activity, histone H2AS121 kinase activity, histone H3S57 kinase activity, histone H4S1 kinase activity, histone H3T3 kinase activity, histone H2BS36 kinase activity, histone H3S28 kinase activity, histone H3T45 kinase activity, histone H2AXS139 kinase activity, Rho-dependent protein serine/threonine kinase activity, histone H3T11 kinase activity, protein serine kinase activity, histone H3T6 kinase activity
GO BP Complete:	chromatin remodeling, cell integrity MAPK cascade, intracellular signal transduction
GO CC Complete:	cellular_component

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=49897\|UniProtKB=Q6A1A2	Homo sapiens	O
HUMAN\|HGNC=8816\|UniProtKB=O15530	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000007655.6\|UniProtKB=A0A2I3TN41	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010499.3\|UniProtKB=G3RXW1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000060539.1\|UniProtKB=F7B371	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000011459.4\|UniProtKB=H9ESX9	Macaca mulatta	O
MOUSE\|MGI=MGI=1338068\|UniProtKB=Q9Z2A0	Mus musculus	O
RAT\|RGD=620307\|UniProtKB=O55173	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000034436.4\|UniProtKB=F1MQJ7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000037719.3\|UniProtKB=A0A287AST6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000000626.4\|UniProtKB=A0A9L0T0A3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000001964.6\|UniProtKB=M3VXM6	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845003792.1\|UniProtKB=A0A8I3MQX7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000016600.4\|UniProtKB=F6ZD74	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000002330.3\|UniProtKB=A0A6I8ND89	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010020316.1\|UniProtKB=A0A8V0Z6Y0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000003492.4\|UniProtKB=H9G7Q7	Anolis carolinensis	O
XENLA\|Gene=pdpk1.L\|UniProtKB=A0A8J0PX21	Xenopus laevis	O
XENLA\|Gene=pdpk1.S\|UniProtKB=A0A1L8EQJ5	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-991549\|UniProtKB=A0A6I8QZN8	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000007757.2\|UniProtKB=H2LUD8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-061013-109\|UniProtKB=Q08BG3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040426-1820\|UniProtKB=Q6NZV1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000003794.1\|UniProtKB=W5M823	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000008253.3\|UniProtKB=F6QZH0	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000007074.3\|UniProtKB=F6WVT9	Ciona intestinalis	O
BRAFL\|Gene=LOC118428892\|UniProtKB=A0A9J7M6H1	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC581490\|UniProtKB=A0A7M7REI2	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003965\|UniProtKB=Q9Y1J3	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG08059\|UniProtKB=A8X5P7	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00021022\|UniProtKB=Q9UA62	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG15660\|UniProtKB=A8XMH2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00090219\|UniProtKB=A0A2A6BQN2	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0020386\|UniProtKB=Q9W0V1	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001471\|UniProtKB=A0A1S4GC66	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC002973\|UniProtKB=D6WGV3	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_299641\|UniProtKB=E9H687	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW021115\|UniProtKB=B7Q978	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG63303\|UniProtKB=T1FXD8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG189040\|UniProtKB=T1FQL0	helobdella robusta	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g84740\|UniProtKB=A7RKQ3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG31577\|UniProtKB=B3S9G1	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_12495\|UniProtKB=A9VCG3	Monosiga brevicollis	O
EREGS\|EnsemblGenome=AGOS_AFR377C\|UniProtKB=Q753D9	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000179865\|UniProtKB=A0A1D8PPB9	Candida albicans	O
CANAL\|Gene_OrderedLocusName=CAALFM_C112410CA\|UniProtKB=Q5A3P6	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B05566g\|UniProtKB=Q6CFM7	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_03110\|UniProtKB=Q5B8M0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G12670\|UniProtKB=Q4WYD7	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03571\|UniProtKB=Q1K4T2	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_13528\|UniProtKB=A7F7E8	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_06367\|UniProtKB=Q0UPE7	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC1778.10c\|UniProtKB=Q9Y7J6	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_05290\|UniProtKB=B6K3A0	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPCC576.15c\|UniProtKB=Q12701	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_02468\|UniProtKB=B6K2J7	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNC05250\|UniProtKB=Q5KJV3	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_05022\|UniProtKB=A0A0D1DX97	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_04828\|UniProtKB=E3K315	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_18429\|UniProtKB=F4NVI4	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_095940\|UniProtKB=C4M3E9	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0284489\|UniProtKB=Q54PK9	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_36122\|UniProtKB=F0ZQF0	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0281471\|UniProtKB=Q54TW2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_56680\|UniProtKB=F0ZSM2	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_30_1000\|UniProtKB=Q4Q7K3	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.6.2450\|UniProtKB=Q584R1	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_31_1530\|UniProtKB=Q4Q6A9	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_15_1550\|UniProtKB=Q4QF23	Leishmania major	O
TRYB2\|Gene_ORFName=Tb09.211.2260\|UniProtKB=Q38DT1	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb09.160.3480\|UniProtKB=Q38F57	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_240510\|UniProtKB=A2EJ98	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_366130\|UniProtKB=A2DHQ7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_179780\|UniProtKB=A2F460	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_035920\|UniProtKB=A2DAR5	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1121900\|UniProtKB=Q8IIE7	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00012278001\|UniProtKB=A0D109	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035808001\|UniProtKB=A0C7B1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026239001\|UniProtKB=A0EF25	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015687001\|UniProtKB=A0DCP1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026762001\|UniProtKB=A0EGJ7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028949001\|UniProtKB=A0BH97	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017845001\|UniProtKB=A0DKE9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00013901001\|UniProtKB=A0D604	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036680001\|UniProtKB=A0CAT2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00011716001\|UniProtKB=A0CZC6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022570001\|UniProtKB=A0E281	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024390001\|UniProtKB=A0E8P4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00023731001\|UniProtKB=A0E6T6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00011455001\|UniProtKB=A0CYI8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00039825001\|UniProtKB=A0DXI4	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_15285\|UniProtKB=B8LDQ0	Thalassiosira pseudonana	O
PHYRM\|Gene=H3H2Y5_PHYRM\|UniProtKB=H3H2Y5	Phytophthora ramorum	O
PHYRM\|Gene=H3G7D1_PHYRM\|UniProtKB=H3G7D1	Phytophthora ramorum	O
PHYRM\|Gene=H3H2Y3_PHYRM\|UniProtKB=H3H2Y3	Phytophthora ramorum	O
PHYRM\|Gene=H3GXW8_PHYRM\|UniProtKB=H3GXW8	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_11g467568v5\|UniProtKB=A0A2K3D7A2	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00001p00226660\|UniProtKB=W1NLJ0	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_182G00450\|UniProtKB=A0A0K9PQW0	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_34G00970\|UniProtKB=A0A0K9P985	Zostera marina	O
MUSAM\|EnsemblGenome=Ma02_g02780\|UniProtKB=A0A804HYM1	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma05_g28400\|UniProtKB=A0A804J9I8	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_001110mg\|UniProtKB=K3XGT9	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3003G372200\|UniProtKB=C5XRA6	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb146330\|UniProtKB=C0P347	Zea mays	O
ORYSJ\|EnsemblGenome=Os01g0872800\|UniProtKB=A0A8J8XIM6	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_2g56460v3\|UniProtKB=I1HTV2	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0298800\|UniProtKB=F2DGV7	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS3D02G376500\|UniProtKB=A0A3B6GYV5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3B02G415800\|UniProtKB=A0A077RXS1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G383400\|UniProtKB=A0A3B6ER47	Triticum aestivum	O
NELNU\|Gene=LOC104612532\|UniProtKB=A0A1U8BAE0	Nelumbo nucifera	O
NELNU\|Gene=LOC104587314\|UniProtKB=A0A1U7Z834	Nelumbo nucifera	O
SPIOL\|Gene=LOC110803688\|UniProtKB=A0A9R0KBY1	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0329251\|UniProtKB=A0A251U4J0	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0540521\|UniProtKB=A0A251T2F0	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C800397890\|UniProtKB=A0A9R1UVU2	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a004635mg\|UniProtKB=A0A022RGQ0	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a025938mg\|UniProtKB=A0A022PZT2	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_08570\|UniProtKB=A0A2G2ZWX3	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400016913\|UniProtKB=M1BEU9	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc03g071750.3\|UniProtKB=A0A3Q7FJB6	Solanum lycopersicum	O
TOBAC\|Gene=LOC107785176\|UniProtKB=A0A1S3ZBS2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107817187\|UniProtKB=A0A1S4CBD3	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_29645\|UniProtKB=A0A1U8EX33	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG402027355\|UniProtKB=M1CM20	Solanum tuberosum	O
TOBAC\|Gene=LOC107772058\|UniProtKB=A0A1S3Y4E2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107771346\|UniProtKB=A0A1S3Y2H4	Nicotiana tabacum	O
VITVI\|Gene_OrderedLocusName=VIT_13s0074g00100\|UniProtKB=F6I5U0	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_J01029\|UniProtKB=A0A059ADR3	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C09P72250.1\|UniProtKB=A0A078I476	Brassica napus	O
BRACM\|EnsemblGenome=Bra009447\|UniProtKB=M4CZ00	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00000385001\|UniProtKB=A0A078F6C3	Brassica napus	O
BRACM\|EnsemblGenome=Bra029850\|UniProtKB=M4EM30	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00072920001\|UniProtKB=A0A078HVH8	Brassica napus	O
BRANA\|EnsemblGenome=GSBRNA2T00072820001\|UniProtKB=A0A078JLF5	Brassica napus	O
BRACM\|EnsemblGenome=Bra034125\|UniProtKB=M4EZ82	Brassica campestris	O
ARATH\|TAIR=locus=2184357\|UniProtKB=Q9XF67	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2075740\|UniProtKB=Q4V3C8	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107904178\|UniProtKB=A0A1U8J6I8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107904334\|UniProtKB=A0A1U8J737	Gossypium hirsutum	O
GOSHI\|Gene=LOC107922041\|UniProtKB=A0A1U8KY46	Gossypium hirsutum	O
GOSHI\|Gene=LOC107960316\|UniProtKB=A0A1U8PPG4	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_043455\|UniProtKB=A0A061FPC8	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g010859mg\|UniProtKB=A0A067EJG1	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_010G232800v3\|UniProtKB=A0A2K1YZ23	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_008G028800v3\|UniProtKB=A0A2K1ZAQ8	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_07G093000\|UniProtKB=A0A2C9VJV6	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_10G054000\|UniProtKB=A0A2C9V3M1	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0008410\|UniProtKB=B9T6S2	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_10G200600\|UniProtKB=I1LCP7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G190000\|UniProtKB=I1NHQ3	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g090917\|UniProtKB=A0A072VPR7	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr14_04280\|UniProtKB=A0A2I4HBU3	Juglans regia	O
JUGRE\|EnsemblGenome=Jr05_03610\|UniProtKB=A0A2I4EM46	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_5G616380\|UniProtKB=A0A0A0KRH7	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_2G204000\|UniProtKB=A0A251QIQ5	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_168798\|UniProtKB=D8R7N6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_164063\|UniProtKB=D8QMJ5	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c26_8560\|UniProtKB=G9F9N7	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0015s0182\|UniProtKB=A0A2R6XH34	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000940100\|UniProtKB=A0A1Y1HTF3	Klebsormidium nitens	O
SACS2\|EnsemblGenome=SSO3207\|UniProtKB=Q97U18	Sulfolobus solfataricus	O