PANTHER Gene Information

Gene Symbol(s):

TRM12

Organism:

Saccharomyces cerevisiae

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Gene Name:

tRNA wybutosine-synthesizing protein 2

Gene ID:

S000004464

Protein ID:

Q04235

Persistent Id:

PTN000582888

Alternate Ids:

D6VZH0(AltAccession)	2.5.1.114(EC)
S000004464(SGD)	TYW2_YEAST(UniProtKB-ID)
DAA09894(EMBL-CDS)	tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase(Synonym)
BK006946(EMBL)	TRM12(Symbol)
YEAST:G3O-32610-MON(BioCyc)	855008(GeneID)
YML005W(Ensembl)	6323638(GI)
YML005W_mRNA(Ensembl_TRS)	NM_001182360(refSeq)
YML005W(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	TRNA METHYLTRANSFERASE (PTHR23245)
PANTHER Subfamily:	TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG (PTHR23245:SF25)
PANTHER GO-slim Molecular Function:	tRNA methyltransferase activity
PANTHER GO-slim Biological Process:	glycosyl compound metabolic process organonitrogen compound biosynthetic process carbohydrate derivative biosynthetic process tRNA methylation
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	RNA methyltransferase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity, tRNA methyltransferase activity, S-adenosylmethionine-dependent methyltransferase activity, transferase activity, transferase activity, transferring alkyl or aryl (other than methyl) groups
GO BP Complete:	tRNA processing, wybutosine biosynthetic process, tRNA methylation, tRNA modification
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=26091\|UniProtKB=Q53H54	Homo sapiens	LDO
MACMU\|Ensembl=ENSMMUG00000015490.4\|UniProtKB=F6YP41	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1915510\|UniProtKB=Q8BG71	Mus musculus	LDO
RAT\|RGD=1307127\|UniProtKB=Q4V8B8	Rattus norvegicus	LDO
BOVIN\|Gene=TRMT12\|UniProtKB=Q58D65	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000020398.5\|UniProtKB=F6RWJ0	Bos taurus	LDO
MONDO\|Ensembl=ENSMODG00000011798.3\|UniProtKB=F7CBL9	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000021403.3\|UniProtKB=F7CVG3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009987.3\|UniProtKB=F6ZRD9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010016742.1\|UniProtKB=A0A8V0YZ63	Gallus gallus	LDO
XENLA\|Gene=trmt12.L\|UniProtKB=A0A1L8F6S2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-992761\|UniProtKB=F7AMM4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001280.2\|UniProtKB=H2L6W7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060825-182\|UniProtKB=Q0P466	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015290.1\|UniProtKB=W5NDV1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000019633.1\|UniProtKB=H2Y0C0	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118431064\|UniProtKB=A0A9J7MB80	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC593691\|UniProtKB=A0A7M7PAK8	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00009586\|UniProtKB=Q20240	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG19351\|UniProtKB=A8XVF2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00099943\|UniProtKB=A0A2A6C9C6	Pristionchus pacificus	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_308692\|UniProtKB=E9H8Q3	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW018117\|UniProtKB=B7PEI9	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG67136\|UniProtKB=T1FYX2	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g84090\|UniProtKB=A7RKB2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG18638\|UniProtKB=B3RLP9	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_28161\|UniProtKB=A9V7D5	Monosiga brevicollis	LDO
EREGS\|EnsemblGenome=AGOS_ADL199W\|UniProtKB=Q75AW9	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000179804\|UniProtKB=A0A1D8PKC5	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D01485g\|UniProtKB=Q6CAM4	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00130\|UniProtKB=Q5BH50	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G11650\|UniProtKB=Q4WVC9	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU10483\|UniProtKB=A7UW71	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_02487\|UniProtKB=A7EB01	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_08634\|UniProtKB=Q0UHY0	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC4G8.06c\|UniProtKB=Q09832	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04735\|UniProtKB=B6K7L9	Schizosaccharomyces japonicus	LDO
PUCGT\|EnsemblGenome=PGTG_07536\|UniProtKB=E3KDD0	Puccinia graminis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_25799\|UniProtKB=B8CG13	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3HBF8_PHYRM\|UniProtKB=H3HBF8	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_14g626634v5\|UniProtKB=A0A2K3CYD6	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00037p00133600\|UniProtKB=U5CVJ2	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_264G00070\|UniProtKB=A0A0K9PEZ1	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma06_g31180\|UniProtKB=A0A804JMD9	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_0287672mg\|UniProtKB=A0A0Q3R7D4	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G317200\|UniProtKB=A0A1B6QEI3	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb322630\|UniProtKB=A0A1D6ID10	Zea mays	LDO
ORYSJ\|Gene_OrderedLocusName=LOC_Os07g33100\|UniProtKB=Q8H4D4	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g26317v3\|UniProtKB=I1GU05	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0141420\|UniProtKB=A0A8I6WMW7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2B02G248800\|UniProtKB=A0A3B6C4M0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G223200\|UniProtKB=A0A3B6AX74	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G229200\|UniProtKB=A0A2X0TSA2	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_024826\|UniProtKB=A0A1U8BMU0	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110777318\|UniProtKB=A0A9R0JKG0	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr05g0193451\|UniProtKB=A0A251UK91	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700348910\|UniProtKB=A0A9R1V3B7	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a000701mg\|UniProtKB=A0A022QMS6	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_15561\|UniProtKB=A0A1U8GRF6	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400023367\|UniProtKB=M1C562	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc05g055610.3\|UniProtKB=A0A3Q7GLB0	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107811207\|UniProtKB=A0A1S4BRT6	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107819037\|UniProtKB=A0A1S4CHW1	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi10g00098\|UniProtKB=F6H7M2	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E04055\|UniProtKB=A0A059CAB1	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00015653001\|UniProtKB=A0A078G994	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra000803\|UniProtKB=M4C9C4	Brassica campestris	LDO
ARATH\|TAIR=locus=2135069\|UniProtKB=Q8W4K1	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107958270\|UniProtKB=A0A1U8PE95	Gossypium hirsutum	O
GOSHI\|Gene=LOC107905930\|UniProtKB=A0A1U8JHT2	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_030223\|UniProtKB=A0A061GNN3	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g036185mg\|UniProtKB=A0A067GF57	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_004G015200v3\|UniProtKB=A0A2K2ANG5	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_16G007200\|UniProtKB=A0A251IXJ0	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0904600\|UniProtKB=B9RXL2	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_07G260400\|UniProtKB=I1KNC8	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g132120\|UniProtKB=G7JJ74	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr03_11170\|UniProtKB=A0A2I4EDW1	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G513770\|UniProtKB=A0A0A0KHU3	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G021000\|UniProtKB=M5X2J6	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_105763\|UniProtKB=D8S0R2	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c9_15020\|UniProtKB=A0A7I4EHK6	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0137s0034\|UniProtKB=A0A2R6W738	Marchantia polymorpha	LDO
METJA\|EnsemblGenome=MJ_1510\|UniProtKB=Q58905	Methanocaldococcus jannaschii	O