PANTHER Gene Information

Gene Symbol(s):

AP2B1

Organism:

Bos taurus

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Tree

Gene Name:

AP-1 complex subunit beta-1

Gene ID:

ENSBTAG00000020316

Protein ID:

Q08DS7

Persistent Id:

PTN007490108

Alternate Ids:

AAI23584(EMBL-CDS)	Beta-1-adaptin(Synonym)
XM_015467951(refSeq)	115497346(GI)
AP1B1_BOVIN(UniProtKB-ID)	BC123583(EMBL)
AP2B1(Symbol)	ENSBTAT00000076585(Ensembl_TRS)
282183(GeneID)	ENSBTAG00000020316(Ensembl)
ENSBTAP00000060816(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER (PTHR11134)
PANTHER Subfamily:	AP-2 COMPLEX SUBUNIT BETA (PTHR11134:SF9)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	vesicle-mediated transport
PANTHER GO-slim Cellular Component:
PANTHER protein class:	membrane traffic protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	clathrin binding
GO BP Complete:	vesicle-mediated transport, intracellular protein transport, endocytosis
GO CC Complete:	clathrin-coated pit, endomembrane system, clathrin adaptor complex, cytoplasmic vesicle, Golgi apparatus, plasma membrane, clathrin-coated vesicle membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Trafficking of AMPA receptors, Adaptive Immune System, WNT5A-dependent internalization of FZD4, Clathrin-mediated endocytosis, Beta-catenin independent WNT signaling, Cargo recognition for clathrin-mediated endocytosis, Signaling by NTRKs, Signal Transduction, VLDLR internalisation and degradation, Vesicle-mediated transport, Glutamate binding, activation of AMPA receptors and synaptic plasticity, Plasma lipoprotein clearance, Retrograde neurotrophin signalling, Axon guidance, Signaling by Receptor Tyrosine Kinases, MHC class II antigen presentation, Membrane Trafficking, Immune System, Transport of small molecules, Developmental Biology, PCP/CE pathway, L1CAM interactions, Signaling by NTRK1 (TRKA), Transmission across Chemical Synapses, Neuronal System, LDL clearance, WNT5A-dependent internalization of FZD2, FZD5 and ROR2, Neurotransmitter receptors and postsynaptic signal transmission, Trafficking of GluR2-containing AMPA receptors, Plasma lipoprotein assembly, remodeling, and clearance, Nervous system development, Recycling pathway of L1, Signaling by WNT

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000043794.1\|UniProtKB=A0A2I3RMI5	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000047694.1\|UniProtKB=A0A2I3SKH9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000039790.1\|UniProtKB=A0A2I2ZLS9	Gorilla gorilla gorilla	O
HUMAN\|HGNC=563\|UniProtKB=P63010	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000009021.6\|UniProtKB=K7CXZ7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015593.3\|UniProtKB=G3RHU1	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=1919020\|UniProtKB=Q9DBG3	Mus musculus	LDO
RAT\|RGD=15003456\|UniProtKB=A0A8I6A4X2	Rattus norvegicus	O
RAT\|RGD=71048\|UniProtKB=P62944	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00005008015.1\|UniProtKB=A0A4X1T854	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000009033.4\|UniProtKB=A0A3Q2LQ45	Equus caballus	LDO
HORSE\|Ensembl=ENSECAG00000009033.4\|UniProtKB=A0A3Q2LQ45	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010390.6\|UniProtKB=A0A337SC44	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000019128.4\|UniProtKB=A0A5F8GR62	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000050274.1\|UniProtKB=A0A6I8MZJ8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029626.1\|UniProtKB=A0A8V1ALB1	Gallus gallus	LDO
XENLA\|Gene=ap2b1.L\|UniProtKB=A0A8J1M541	Xenopus laevis	O
XENLA\|Gene=ap2b1.S\|UniProtKB=A0A8J1ME92	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5871354\|UniProtKB=A0A6I8S667	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000014475.2\|UniProtKB=H2MHN6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-6564\|UniProtKB=Q6NYJ9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001756.1\|UniProtKB=W5M0Z7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000021069.1\|UniProtKB=H2XLC2	Ciona intestinalis	O
BRAFL\|Gene=LOC118430441\|UniProtKB=A0A9J7NC18	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC767501\|UniProtKB=A0A7M7P935	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00000160\|UniProtKB=Q9N4F3	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00031341\|UniProtKB=A8X9Q7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00091984\|UniProtKB=A0A2A6BQS7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0010380\|UniProtKB=Q24253	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001267\|UniProtKB=Q7PX81	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC015061\|UniProtKB=D2A641	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_324067\|UniProtKB=E9H0L3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_337718\|UniProtKB=E9I210	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW011108\|UniProtKB=B7Q6V9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG187670\|UniProtKB=T1FPB8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG193557\|UniProtKB=T1FV47	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g190491\|UniProtKB=A7SJK8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG57237\|UniProtKB=B3RYW3	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_12202\|UniProtKB=A9VBI8	Monosiga brevicollis	O
YEAST\|SGD=S000003765\|UniProtKB=P27351	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADR342C\|UniProtKB=Q759D5	Eremothecium gossypii	O
CANAL\|CGD=CAL0000195418\|UniProtKB=A0A1D8PFU6	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E15598g\|UniProtKB=Q6C5S4	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05950\|UniProtKB=C8V3G8	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G10340\|UniProtKB=Q4X1D6	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU05232\|UniProtKB=Q7S8H6	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_08464\|UniProtKB=A7ET09	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_13536\|UniProtKB=Q0U3X8	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC2G2.06c\|UniProtKB=O43005	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00104\|UniProtKB=B6JXG5	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNB04170\|UniProtKB=Q5KLT1	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_04249\|UniProtKB=A0A0D1DVL0	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_14472\|UniProtKB=E3KVP8	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_1105\|UniProtKB=F4P1M3	Batrachochytrium dendrobatidis	O
YEAST\|SGD=S000001618\|UniProtKB=P36000	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFR200W\|UniProtKB=Q753X2	Eremothecium gossypii	O
CANAL\|CGD=CAL0000200918\|UniProtKB=A0A1D8PJI6	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F21769g\|UniProtKB=Q6C0U1	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_03029\|UniProtKB=Q5B8V1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G08970\|UniProtKB=Q4WXC2	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU09721\|UniProtKB=Q7S2Q5	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_11848\|UniProtKB=A7F3K2	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_02752\|UniProtKB=Q0UZR2	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC947.02\|UniProtKB=O43079	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04565\|UniProtKB=B6K759	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNH03830\|UniProtKB=Q5KDA3	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNL03830\|UniProtKB=Q5K906	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10158\|UniProtKB=A0A0D1E1W3	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_09932\|UniProtKB=E3KFD7	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_87982\|UniProtKB=F4P1I7	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_058450\|UniProtKB=C4M5F2	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_081400\|UniProtKB=B1N3T8	Entamoeba histolytica	O
ENTH1\|Gene_ORFName=EHI_013040\|UniProtKB=B1N2V8	Entamoeba histolytica	O
ENTH1\|Gene_ORFName=EHI_023600\|UniProtKB=A0A8U0WPZ3	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0279141\|UniProtKB=Q54X82	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_48016\|UniProtKB=F0ZMF1	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_11_0990\|UniProtKB=Q4QGY0	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_36_6770\|UniProtKB=Q4Q078	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.6k15.2500\|UniProtKB=Q38AG0	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_15339\|UniProtKB=E2RU20	Giardia intestinalis	O
GIAIC\|EnsemblGenome=GL50803_21423\|UniProtKB=A8B9U8	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_267630\|UniProtKB=A2DLB3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_430250\|UniProtKB=A2E351	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_280470\|UniProtKB=A2DRG8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_237070\|UniProtKB=A2DCQ7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_456570\|UniProtKB=A2DBY1	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_136530\|UniProtKB=A2DJD5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_397260\|UniProtKB=A2DXB3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_477740\|UniProtKB=A2G248	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_055150\|UniProtKB=A2ETI3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_006350\|UniProtKB=A2E742	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_373190\|UniProtKB=A2DZI2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_287780\|UniProtKB=A2ER45	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_021050\|UniProtKB=A2DH87	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_439460\|UniProtKB=A2FAG5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_035540\|UniProtKB=A2DAM8	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_0613500\|UniProtKB=C6KSX7	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_0528100\|UniProtKB=Q8I3I6	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00015502001\|UniProtKB=A0DC58	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012069001\|UniProtKB=A0D0F0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016812001\|UniProtKB=A0DHA8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037033001\|UniProtKB=A0CBT3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017058001\|UniProtKB=A0DI20	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037357001\|UniProtKB=A0CCQ5	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_41687\|UniProtKB=B8C7W7	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GA38_PHYRM\|UniProtKB=H3GA38	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_11g478156v5\|UniProtKB=A0A2K3D8H2	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00102p00095780\|UniProtKB=W1NY12	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_35G00840\|UniProtKB=A0A0K9P8S1	Zostera marina	O
MUSAM\|EnsemblGenome=Ma03_g13780\|UniProtKB=A0A804IBR9	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma01_g18260\|UniProtKB=A0A804HVJ5	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_034151mg\|UniProtKB=K4A5J7	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G369000\|UniProtKB=C5WZP4	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb394540\|UniProtKB=K7WDG3	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb041950\|UniProtKB=A0A804LWN2	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb017130\|UniProtKB=A0A804LKG3	Zea mays	O
ORYSJ\|EnsemblGenome=Os03g0355600\|UniProtKB=Q0DRT9	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g62210v3\|UniProtKB=I1H5D9	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0374910\|UniProtKB=F2DKP3	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4A02G166200\|UniProtKB=A0A3B6HX39	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G166700\|UniProtKB=A0A3B6JI13	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G165000\|UniProtKB=A0A3B6IP72	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_016647\|UniProtKB=A0A1U8AIA1	Nelumbo nucifera	O
NELNU\|Gene=LOC104603666\|UniProtKB=A0A1U8ASJ1	Nelumbo nucifera	O
SPIOL\|Gene=LOC110784953\|UniProtKB=A0A9R0JSM6	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0604881\|UniProtKB=A0A251SVW3	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0576991\|UniProtKB=A0A251SPF8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C300104730\|UniProtKB=A0A9R1W3N3	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C600301000\|UniProtKB=A0A9R1V9Y5	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a001261mg\|UniProtKB=A0A022RK07	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_19226\|UniProtKB=A0A2G2Z171	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_00257\|UniProtKB=A0A1U8GF20	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400012194\|UniProtKB=M1AW83	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc08g081320.3\|UniProtKB=A0A3Q7HW92	Solanum lycopersicum	O
TOBAC\|Gene=LOC107832035\|UniProtKB=A0A1S4DPH0	Nicotiana tabacum	O
TOBAC\|Gene=LOC107805886\|UniProtKB=A0A1S4B9A2	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi02g00008\|UniProtKB=D7TV41	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_D01829\|UniProtKB=A0A059CGB9	Eucalyptus grandis	O
BRACM\|EnsemblGenome=Bra019302\|UniProtKB=M4DS09	Brassica campestris	O
ARATH\|TAIR=locus=2117924\|UniProtKB=O81742	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=DARMORV10_C09P35180.1\|UniProtKB=A0A078FJS2	Brassica napus	O
BRACM\|EnsemblGenome=Bra035228\|UniProtKB=M4F2D0	Brassica campestris	O
ARATH\|TAIR=locus=2128313\|UniProtKB=Q9SUS3	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107941520\|UniProtKB=A0A1U8MYC8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107887508\|UniProtKB=A0A1U8HTH2	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_016300\|UniProtKB=A0A061GCM9	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_001G101400v3\|UniProtKB=B9GKF2	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_003G130400v3\|UniProtKB=B9GWT9	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_02G136100\|UniProtKB=A0A2C9WF40	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0786070\|UniProtKB=B9SB76	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_01G227000\|UniProtKB=I1JAF7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_11G015700\|UniProtKB=I1LG61	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_12G021600\|UniProtKB=I1LPD3	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_11G095500\|UniProtKB=I1LIM0	Glycine max	O
MEDTR\|EnsemblGenome=MTR_4g076210\|UniProtKB=G7JQK3	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr09_10780\|UniProtKB=A0A2I4FBX7	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_5G152950\|UniProtKB=A0A0A0KK76	Cucumis sativus	O
CUCSA\|EnsemblGenome=Csa_7G041890\|UniProtKB=A0A0A0K1I7	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_5G103900\|UniProtKB=M5WE51	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_269606\|UniProtKB=D8T384	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_269184\|UniProtKB=D8SU50	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c1_19340\|UniProtKB=A9S2H0	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c2_18140\|UniProtKB=A9TPL0	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c14_2460\|UniProtKB=A9TVR6	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0002s0295\|UniProtKB=A0A2R6XUR7	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000190470\|UniProtKB=A0A1Y1HNR7	Klebsormidium nitens	O