PANTHER Gene Information   
Gene Symbol(s): btl
Organism: Drosophila melanogaster
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: Fibroblast growth factor receptor homolog 2
Gene ID: FBgn0285896
Protein ID: Q09147
Persistent Id: PTN000699374
Alternate Ids:
btl(Symbol) 2.7.10.1(EC)
S55971(EMBL) FBtr0100676(Ensembl_TRS)
FR2(Synonym) FBpp0100143(Ensembl_PRO)
A4V1Y3(AltAccession) FGFR2_DROME(UniProtKB-ID)
CAA05753(EMBL-CDS) NM_001014583(refSeq)
205371789(GI) FBgn0285896(Ensembl)
39564(GeneID) FBgn0285896(FlyBase)
Show All

PANTHER Classification
PANTHER Family: TYROSINE-PROTEIN KINASE RECEPTOR (PTHR24416)
PANTHER Subfamily: FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1-RELATED (PTHR24416:SF550)  
PANTHER GO-slim Molecular Function: transmembrane receptor protein tyrosine kinase activity
PANTHER GO-slim Biological Process: transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
positive regulation of kinase activity
PANTHER GO-slim Cellular Component: receptor complex
plasma membrane
PANTHER protein class: transmembrane signal receptor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: fibroblast growth factor receptor activity, ATP binding, protein tyrosine kinase activity, protein binding, transmembrane receptor protein tyrosine kinase activity
GO BP Complete: multicellular organism development, positive regulation of cell population proliferation, fibroblast growth factor receptor signaling pathway, border follicle cell migration, terminal branching, open tracheal system, positive regulation of synaptic assembly at neuromuscular junction, branching involved in open tracheal system development, glial cell migration, secondary branching, open tracheal system, epithelial cell migration, open tracheal system, primary branching, open tracheal system, compound eye morphogenesis, positive regulation of kinase activity, genital disc development, terminal cell fate specification, open tracheal system, epithelial cell type specification, open tracheal system, cell surface receptor protein tyrosine kinase signaling pathway, trachea development, negative regulation of plasmatocyte differentiation, tracheal outgrowth, open tracheal system, filopodium assembly, open tracheal system development, negative regulation of axon extension, negative regulation of crystal cell differentiation, positive regulation of melanization defense response, branch fusion, open tracheal system, tracheal pit formation in open tracheal system, lumen formation, open tracheal system
GO CC Complete: cytoneme, receptor complex, plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: FGFR3c ligand binding and activation, FGFR1c ligand binding and activation, FGFR1b ligand binding and activation, FGFR3b ligand binding and activation, PI-3K cascade:FGFR2, Downstream signaling of activated FGFR2, FGFR2b ligand binding and activation, FGFR1c and Klotho ligand binding and activation, MAPK family signaling cascades, FRS-mediated FGFR1 signaling, Signal Transduction, FGFR2c ligand binding and activation, Negative regulation of FGFR3 signaling, Signaling by Receptor Tyrosine Kinases, SHC-mediated cascade:FGFR2, Negative regulation of FGFR4 signaling, Phospholipase C-mediated cascade: FGFR1, Signaling by FGFR1, Signaling by FGFR2, RAF/MAP kinase cascade, PI3K Cascade, PIP3 activates AKT signaling, MAPK1/MAPK3 signaling, Negative regulation of the PI3K/AKT network, FGFR2 ligand binding and activation, Signaling by Insulin receptor, Insulin receptor signalling cascade, FGFR4 ligand binding and activation, FGFR1 ligand binding and activation, SHC-mediated cascade:FGFR1, PI-3K cascade:FGFR1, Intracellular signaling by second messengers, Downstream signaling of activated FGFR1, PI-3K cascade:FGFR4, Negative regulation of FGFR1 signaling, Negative regulation of FGFR2 signaling, PI-3K cascade:FGFR3, Signaling by FGFR, FGFR3 ligand binding and activation, FRS-mediated FGFR4 signaling, SHC-mediated cascade:FGFR4, Downstream signaling of activated FGFR4, IRS-related events triggered by IGF1R, IGF1R signaling cascade, betaKlotho-mediated ligand binding, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Phospholipase C-mediated cascade; FGFR2, Signaling by FGFR4, FRS-mediated FGFR2 signaling, Phospholipase C-mediated cascade; FGFR3, Signaling by FGFR3, SHC-mediated cascade:FGFR3, Phospholipase C-mediated cascade; FGFR4, IRS-mediated signalling, Downstream signaling of activated FGFR3, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, FRS-mediated FGFR3 signaling

Orthologs