PANTHER Gene Information

Gene Symbol(s):

tpp-2

Organism:

Caenorhabditis elegans

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Gene Name:

Tripeptidyl-peptidase 2

Gene ID:

WBGene00017686

Protein ID:

Q09541

Persistent Id:

PTN000083050

Alternate Ids:

2499873(GI)	3.4.14.10 {ECO:0000250\|UniProtKB:P29144}(EC)
CE01917(WormBase_PRO)	F21H12(WormBase_TRS)
174018(GeneID)	WBGene00017686(WormBase)
Tripeptidyl aminopeptidase(Synonym)	F21H12.6(Ensembl_PRO)
WBGene00017686(Ensembl)	F21H12.6(Ensembl_TRS)
FO080717(EMBL)	CCD66120(EMBL-CDS)
TPP2_CAEEL(UniProtKB-ID)	tpp-2(Symbol)
NM_062820(refSeq)
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PANTHER Classification

PANTHER Family:	PEPTIDASE S8 (PTHR43806)
PANTHER Subfamily:	TRIPEPTIDYL-PEPTIDASE 2 (PTHR43806:SF14)
PANTHER GO-slim Molecular Function:	exopeptidase activity serine-type endopeptidase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	serine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	tripeptidyl-peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity, aminopeptidase activity
GO BP Complete:	proteolysis, positive regulation of lipid storage
GO CC Complete:	cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Class I MHC mediated antigen processing & presentation, Immune System, Antigen processing: Ubiquitination & Proteasome degradation, Adaptive Immune System

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12016\|UniProtKB=P29144	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006009.7\|UniProtKB=K7B2P3	Pan troglodytes	LDO
MOUSE\|MGI=MGI=102724\|UniProtKB=Q64514	Mus musculus	LDO
RAT\|RGD=621584\|UniProtKB=Q64560	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020389.6\|UniProtKB=A0A3Q1M996	Bos taurus	LDO
BOVIN\|Gene=TPP2\|UniProtKB=A5PK39	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000009528.5\|UniProtKB=A0A287AL38	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000000631.4\|UniProtKB=A0A3Q2KK21	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000004200.6\|UniProtKB=A0A2I2ULY1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845026639.1\|UniProtKB=A0A8I3QCC9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006272.4\|UniProtKB=A0A5F8GYJ1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011311.4\|UniProtKB=A0A6I8NGV0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010005174.1\|UniProtKB=A0A1D5P774	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002987.4\|UniProtKB=R4GC74	Anolis carolinensis	LDO
XENLA\|Gene=tpp2.S\|UniProtKB=A0A1L8H901	Xenopus laevis	O
XENLA\|Gene=tpp2.L\|UniProtKB=Q6GQZ3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-922547\|UniProtKB=F6RTC3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000004938.2\|UniProtKB=H2LJN9	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-121214-290\|UniProtKB=R4GDQ0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010014.1\|UniProtKB=W5MV60	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007942.3\|UniProtKB=F6ZRN0	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118427335\|UniProtKB=A0A9J7M2T4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC583848\|UniProtKB=A0A7M7NP45	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00025600\|UniProtKB=A8WU07	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00113345\|UniProtKB=A0A2A6BF85	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0020370\|UniProtKB=Q9V6K1	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004870\|UniProtKB=Q7Q974	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC034512\|UniProtKB=A0A139WPG7	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_186919\|UniProtKB=E9FS53	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW006099\|UniProtKB=B7PQH8	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG107485\|UniProtKB=T1EEA8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g176183\|UniProtKB=A7T1C0	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG61672\|UniProtKB=B3SBM8	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_34612\|UniProtKB=A9VCV5	Monosiga brevicollis	LDO
SCHPO\|PomBase=SPAP8A3.12c\|UniProtKB=Q9UT05	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04928\|UniProtKB=B6K851	Schizosaccharomyces japonicus	LDO
USTMA\|EnsemblGenome=UMAG_12106\|UniProtKB=A0A0D1ECZ9	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_92717\|UniProtKB=F4PEI3	Batrachochytrium dendrobatidis	LDO
CHLRE\|EnsemblGenome=CHLRE_02g076950v5\|UniProtKB=A0A2K3E088	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_10g459450v5\|UniProtKB=A0A2K3DBR5	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_16g675350v5\|UniProtKB=A0A2K3CVF8	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00009p00251110\|UniProtKB=W1NHW6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_25G00120\|UniProtKB=A0A0K9PHF1	Zostera marina	LDO
SETIT\|EnsemblGenome=SETIT_016106mg\|UniProtKB=K3YPB4	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G290000\|UniProtKB=C5Y1E8	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb249900\|UniProtKB=A0A1D6HFC3	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0664300\|UniProtKB=Q6ESI7	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g51020v3\|UniProtKB=I1ICD4	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0601930\|UniProtKB=A0A8I7BC59	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6D02G228700\|UniProtKB=A0A3B6QIX7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G246300\|UniProtKB=A0A3B6NRW7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G278200\|UniProtKB=A0A3B6PPY5	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_020371\|UniProtKB=A0A1U8A1B2	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110784171\|UniProtKB=A0A9R0I8U5	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr13g0575761\|UniProtKB=A0A9K3EG82	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr10g0304171\|UniProtKB=A0A251TLH4	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800392020\|UniProtKB=A0A9R1X122	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a000305mg\|UniProtKB=A0A022QCW4	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_09358\|UniProtKB=A0A2G2ZZ45	Capsicum annuum	LDO
TOBAC\|Gene=LOC107798947\|UniProtKB=A0A1S4AL63	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107784804\|UniProtKB=A0A1S3ZAR8	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi16g01897\|UniProtKB=F6H6M8	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_A027801\|UniProtKB=A0A059DJV6	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_A02778\|UniProtKB=A0A059DJY9	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra013477\|UniProtKB=M4DAG7	Brassica campestris	O
BRACM\|EnsemblGenome=Bra038797\|UniProtKB=M4FCH8	Brassica campestris	LDO
ARATH\|TAIR=locus=2133039\|UniProtKB=F4JVN6	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107904614\|UniProtKB=A0A1U8JCX3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107952372\|UniProtKB=A0A1U8NVY4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107923906\|UniProtKB=A0A1U8L4M4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107917752\|UniProtKB=A0A1U8KJC6	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_015183\|UniProtKB=A0A061G866	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g000645mg\|UniProtKB=A0A067E9Y5	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_015G145300v3\|UniProtKB=A0A2K1XN05	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_012G142200v3\|UniProtKB=B9I485	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_06G148500\|UniProtKB=A0A2C9VT12	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1583430\|UniProtKB=B9RIX4	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_09G137200\|UniProtKB=A0A0R0I854	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_16G182500\|UniProtKB=I1MPM3	Glycine max	O
MEDTR\|EnsemblGenome=MTR_0025s0060\|UniProtKB=A0A072TK75	Medicago truncatula	O
SOYBN\|EnsemblGenome=GLYMA_10G234500\|UniProtKB=I1LDQ6	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g101030\|UniProtKB=G7IAM4	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr10_09040\|UniProtKB=A0A2I4F9P9	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G166400\|UniProtKB=A0A0A0KRE6	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G295900\|UniProtKB=A0A251QNC3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_144433\|UniProtKB=D8R7G9	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_74857\|UniProtKB=D8QMQ5	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c2_32420\|UniProtKB=A0A2K1L404	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c7_23000\|UniProtKB=A0A2K1KCP0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0069s0029\|UniProtKB=A0A2R6WPB9	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003780050\|UniProtKB=A0A1Y1IEG1	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_1545\|UniProtKB=A9A4Y7	Nitrosopumilus maritimus	O
HALSA\|EnsemblGenome=VNG_1951G\|UniProtKB=Q9HNT7	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_2573G\|UniProtKB=Q9HMF2	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0076\|UniProtKB=Q5JEH9	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_1909\|UniProtKB=A9WDW5	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_2635\|UniProtKB=A9WIW4	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO1824\|UniProtKB=Q9RJ44	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO2637\|UniProtKB=Q9L1Z8	Streptomyces coelicolor	O
CLOBH\|Gene_OrderedLocusName=CBO2322\|UniProtKB=A5I492	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr1771\|UniProtKB=Q8DNF3	Streptococcus pneumoniae	O
STRR6\|EnsemblGenome=spr0561\|UniProtKB=Q8DQP7	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_01949\|UniProtKB=Q2FXB6	Staphylococcus aureus	O
BACSU\|EnsemblGenome=BSU_17260\|UniProtKB=O31788	Bacillus subtilis	O
BACSU\|EnsemblGenome=BSU_38090\|UniProtKB=P29141	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4869\|UniProtKB=Q816G4	Bacillus cereus	O
BACCR\|EnsemblGenome=BC_4351\|UniProtKB=Q818B5	Bacillus cereus	O
BACCR\|EnsemblGenome=BC_3412\|UniProtKB=Q81AY5	Bacillus cereus	O
BACCR\|EnsemblGenome=BC_2316\|UniProtKB=Q81DP0	Bacillus cereus	O
DEIRA\|EnsemblGenome=DR_B0069\|UniProtKB=Q9RZQ1	Deinococcus radiodurans	O
DEIRA\|EnsemblGenome=DR_A0283\|UniProtKB=Q9RYM8	Deinococcus radiodurans	O
DEIRA\|EnsemblGenome=DR_1536\|UniProtKB=Q9RU58	Deinococcus radiodurans	O
DEIRA\|EnsemblGenome=DR_1937\|UniProtKB=Q9RT31	Deinococcus radiodurans	O
GLOVI\|Gene=Q7NKC4_GLOVI\|UniProtKB=Q7NKC4	Gloeobacter violaceus	O
SYNY3\|Gene=Q55477_SYNY3\|UniProtKB=Q55477	Synechocystis	O
RHOBA\|EnsemblGenome=RB9765\|UniProtKB=Q7UL36	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB13186\|UniProtKB=Q7UHI0	Rhodopirellula baltica	O
FUSNN\|EnsemblGenome=FN2100\|UniProtKB=Q8RHD7	Fusobacterium nucleatum	O
GEOSL\|EnsemblGenome=GSU2075\|UniProtKB=Q74BG6	Geobacter sulfurreducens	O
BRADU\|Gene=papA\|UniProtKB=Q89SV6	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89QT0_BRADU\|UniProtKB=Q89QT0	Bradyrhizobium diazoefficiens	O
SHEON\|Gene_OrderedLocusName=SO_3800\|UniProtKB=Q8EAU2	Shewanella oneidensis	O
SHEON\|Gene_OrderedLocusName=SO_0187\|UniProtKB=Q8EKA8	Shewanella oneidensis	O
XANCP\|EnsemblGenome=XCC0659\|UniProtKB=Q8PCQ4	Xanthomonas campestris	O
XANCP\|EnsemblGenome=XCC0854\|UniProtKB=Q8PC81	Xanthomonas campestris	O
XANCP\|EnsemblGenome=XCC0851\|UniProtKB=P23314	Xanthomonas campestris	O
XANCP\|EnsemblGenome=XCC1298\|UniProtKB=Q8PB28	Xanthomonas campestris	O
XANCP\|EnsemblGenome=XCC0852\|UniProtKB=Q8PC83	Xanthomonas campestris	O