PANTHER Gene Information

Gene Symbol(s):

eme2

Organism:

Xenopus tropicalis

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Gene Name:

Probable crossover junction endonuclease EME2

Gene ID:

XB-GENE-5926460

Protein ID:

Q0IHN5

Persistent Id:

PTN001078417

Alternate Ids:

XM_012970576(refSeq)	780321(GeneID)
eme2(Symbol)	EME2_XENTR(UniProtKB-ID)
BC123066(EMBL)	EME2(Synonym)
118404026(GI)	AAI23067(EMBL-CDS)
3.1.22.-(EC)
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PANTHER Classification

PANTHER Family:	EME1 PROTEIN (PTHR21077)
PANTHER Subfamily:	CROSSOVER JUNCTION ENDONUCLEASE EME2-RELATED (PTHR21077:SF6)
PANTHER GO-slim Molecular Function:	DNA endonuclease activity
PANTHER GO-slim Biological Process:	replication fork processing mitotic intra-S DNA damage checkpoint signaling double-strand break repair resolution of meiotic recombination intermediates
PANTHER GO-slim Cellular Component:	endonuclease complex
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA binding, endonuclease activity, nuclease activity, crossover junction DNA endonuclease activity
GO BP Complete:	DNA repair, DNA recombination, resolution of meiotic recombination intermediates, replication fork processing, mitotic intra-S DNA damage checkpoint signaling, double-strand break repair
GO CC Complete:	nucleus, Holliday junction resolvase complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

HDR through Homologous Recombination (HRR), DNA Double-Strand Break Repair, Resolution of D-Loop Structures, Homology Directed Repair, HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), DNA Repair, Resolution of D-loop Structures through Holliday Junction Intermediates

Orthologs

ID	Organism	Type
HUMAN\|HGNC=27289\|UniProtKB=A4GXA9	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007607.6\|UniProtKB=H2RHN9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006238.3\|UniProtKB=G3QTS0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000060835.1\|UniProtKB=A0A5F7ZE88	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1919889\|UniProtKB=Q56A04	Mus musculus	LDO
RAT\|RGD=1304924\|UniProtKB=D3ZC60	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000016553.5\|UniProtKB=E1B7C9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000021467.3\|UniProtKB=I3LE59	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016045.3\|UniProtKB=F6TA20	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000011728.6\|UniProtKB=M3WFM9	Felis catus	LDO
CHICK\|Ensembl=ENSGALG00010018480.1\|UniProtKB=A0A8V0Z7R1	Gallus gallus	LDO
XENLA\|Gene=eme2.L\|UniProtKB=A0A1L8EY99	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000030257.1\|UniProtKB=A0A3B3H9B3	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000002257.1\|UniProtKB=W5M2P1	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118428853\|UniProtKB=A0A9J7N8B6	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100889179\|UniProtKB=A0A7M7NRY6	Strongylocentrotus purpuratus	O
PRIPA\|EnsemblGenome=WBGene00094558\|UniProtKB=A0A2A6CE15	Pristionchus pacificus	O
TRICA\|EnsemblGenome=TC032180\|UniProtKB=A0A139WN59	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_95947\|UniProtKB=E9FWF9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_305758\|UniProtKB=E9GSG9	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG193600\|UniProtKB=T1FV59	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g240773\|UniProtKB=A7RUE5	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_26875\|UniProtKB=A9V3S9	Monosiga brevicollis	O
YEAST\|SGD=S000000302\|UniProtKB=P38257	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADL318C\|UniProtKB=Q75B88	Eremothecium gossypii	O
CANAL\|CGD=CAL0000198284\|UniProtKB=A0A1D8PPF7	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E33715g\|UniProtKB=Q6C3M0	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_06878\|UniProtKB=Q5AXV2	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G13220\|UniProtKB=Q4WVT2	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU06826\|UniProtKB=F5HH93	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_02493\|UniProtKB=A7EB07	Sclerotinia sclerotiorum	O
SCHPO\|PomBase=SPAPB1E7.06c\|UniProtKB=Q9C103	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00623\|UniProtKB=B6JW53	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNK00980\|UniProtKB=Q5K9S0	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_05201\|UniProtKB=A0A0D1E1Y0	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_10837\|UniProtKB=E3KK53	Puccinia graminis	O
AMBTC\|EnsemblGenome=AMTR_s00046p00048650\|UniProtKB=U5D930	Amborella trichopoda	O
MUSAM\|EnsemblGenome=Ma06_g04600\|UniProtKB=A0A804JCM5	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_009675mg\|UniProtKB=K3Y636	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3006G240300\|UniProtKB=C5Y925	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb068550\|UniProtKB=A0A1D6DW59	Zea mays	O
ORYSJ\|EnsemblGenome=Os04g0648700\|UniProtKB=Q0J9J6	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_5g23984v3\|UniProtKB=A0A2K2CIZ6	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_5g23976v3\|UniProtKB=A0A0Q3GVB8	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0204920\|UniProtKB=A0A8I6WWT5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2A02G514600\|UniProtKB=A0A3B6B7C2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G516200\|UniProtKB=A0A3B6DKK7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G542900\|UniProtKB=A0A3B6CH97	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0204940\|UniProtKB=A0A8I6XR20	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2B02G543100\|UniProtKB=A0A3B6CEU9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G516300\|UniProtKB=A0A3B6DLT5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G514800\|UniProtKB=A0A3B6B6S1	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_014435\|UniProtKB=A0A1U8A3S6	Nelumbo nucifera	O
SPIOL\|Gene=LOC110786273\|UniProtKB=A0A9R0IC18	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0385851\|UniProtKB=A0A251TVQ8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400210740\|UniProtKB=A0A9R1VSL2	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a019811mg\|UniProtKB=A0A022Q7Y4	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_30014\|UniProtKB=A0A2G2Y7D1	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc04g051490.3\|UniProtKB=A0A3Q7G4W9	Solanum lycopersicum	O
TOBAC\|Gene=LOC107825442\|UniProtKB=A0A1S4D2Y0	Nicotiana tabacum	O
TOBAC\|Gene=LOC107822427\|UniProtKB=A0A1S4CTY3	Nicotiana tabacum	O
VITVI\|Gene_OrderedLocusName=VIT_07s0031g01900\|UniProtKB=D7SW92	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_I00295\|UniProtKB=A0A059AKW1	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00090219001\|UniProtKB=A0A078FU23	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C04P50950.1\|UniProtKB=A0A078IA78	Brassica napus	O
BRACM\|EnsemblGenome=Bra030277\|UniProtKB=M4ENA7	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A09P57740.1\|UniProtKB=A0A078FN39	Brassica napus	O
BRACM\|EnsemblGenome=Bra041082\|UniProtKB=M4FJ03	Brassica campestris	O
ARATH\|TAIR=locus=2052484\|UniProtKB=Q84M98	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2055961\|UniProtKB=C5H8J1	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107914475\|UniProtKB=A0A1U8KD60	Gossypium hirsutum	O
GOSHI\|Gene=LOC107914408\|UniProtKB=A0A1U8K8H4	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_001297\|UniProtKB=A0A061DK03	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_007G077400v3\|UniProtKB=A0A2K1ZQX4	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_12G145400\|UniProtKB=A0A2C9UWL5	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0075770\|UniProtKB=B9SW94	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_08G144700\|UniProtKB=K7L6Q1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_05G186200\|UniProtKB=K7KR30	Glycine max	O
MEDTR\|EnsemblGenome=MTR_8g092300\|UniProtKB=G7LC63	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr01_15410\|UniProtKB=A0A2I4ETD4	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_6G486820\|UniProtKB=A0A0A0KHY1	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G550600\|UniProtKB=A0A251RI53	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_6G166800\|UniProtKB=A0A251NRI7	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_430219\|UniProtKB=D8T8Q9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_428406\|UniProtKB=D8T2Q4	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c5_3310\|UniProtKB=A0A2K1KIA7	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0041s0060\|UniProtKB=A0A2R6X224	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000570090\|UniProtKB=A0A0U9HIR3	Klebsormidium nitens	O