PANTHER Gene Information

Gene Symbol(s):

crn-4

Organism:

Caenorhabditis elegans

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Gene Name:

Cell death-related nuclease 4

Gene ID:

WBGene00000797

Protein ID:

Q10905

Persistent Id:

PTN000549083

Alternate Ids:

180536(GeneID)	crn-4(Symbol)
CHEMBL3879829(ChEMBL)	CE03858(WormBase_PRO)
FO080097(EMBL)	219109277(GI)
AH9(WormBase_TRS)	WBGene00000797(WormBase)
Cell death-related nuclease 4(Synonym)	AH9.2(Ensembl_PRO)
CCD61184(EMBL-CDS)	AH9.2(Ensembl_TRS)
3.1.-.-(EC)	WBGene00000797(Ensembl)
CRN4_CAEEL(UniProtKB-ID)	NM_076014(refSeq)
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PANTHER Classification

PANTHER Family:	3'-5' EXONUCLEASE ERI1-RELATED (PTHR23044)
PANTHER Subfamily:	CELL DEATH-RELATED NUCLEASE 4 (PTHR23044:SF4)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	exoribonuclease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	nucleic acid binding, 3'-5' exonuclease activity, 3'-5'-RNA exonuclease activity, DNA nuclease activity, exonuclease activity, metal ion binding, RNA nuclease activity, DNA endonuclease activity, single-stranded DNA binding
GO BP Complete:	DNA catabolic process, apoptotic DNA fragmentation, apoptotic process, exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), RNA catabolic process
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=23994\|UniProtKB=Q8IV48	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000050102.1\|UniProtKB=A0A2I3TXS5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013059.3\|UniProtKB=G3RBA0	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000008867.4\|UniProtKB=H9EX66	Macaca mulatta	O
MOUSE\|MGI=MGI=1914526\|UniProtKB=Q7TMF2	Mus musculus	O
RAT\|RGD=1308378\|UniProtKB=Q5FVR4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000048265.2\|UniProtKB=A0A3Q1MXJ4	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000009685.3\|UniProtKB=Q32LA2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000033634.2\|UniProtKB=A0A287AID0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000011091.3\|UniProtKB=A0A3Q2GWA9	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000029808.4\|UniProtKB=M3WT29	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845013010.1\|UniProtKB=A0A8I3NR15	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000040174.1\|UniProtKB=A0A5F8HC71	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000042020.1\|UniProtKB=A0A6I8P4S5	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010003034.1\|UniProtKB=A0A8V0XCA0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000002863.4\|UniProtKB=H9G6U1	Anolis carolinensis	O
XENLA\|Gene=eri1.L\|UniProtKB=Q4QQX7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-974172\|UniProtKB=Q28FF6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000025831.1\|UniProtKB=A0A3B3HI41	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050522-39\|UniProtKB=Q503G0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012161.1\|UniProtKB=W5N2U9	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000006175.3\|UniProtKB=F7BKG7	Ciona intestinalis	O
BRAFL\|Gene=LOC118429274\|UniProtKB=A0A9J7M6E7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118414733\|UniProtKB=A0A9J7L2R7	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC754917\|UniProtKB=A0A7M7G117	Strongylocentrotus purpuratus	O
CAEBR\|Gene_ORFName=CBG02004\|UniProtKB=A8WRS4	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00034683\|UniProtKB=A8XJ89	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00032875\|UniProtKB=A8XE35	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00025157\|UniProtKB=A8WRS9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00025149\|UniProtKB=A8WRS1	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG23882\|UniProtKB=A8WJI0	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00025148\|UniProtKB=A8WRS0	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00025151\|UniProtKB=A8WRS3	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00034684\|UniProtKB=A8XJ90	Caenorhabditis briggsae	LDO
CAEBR\|WormBase=WBGene00034685\|UniProtKB=A8XJ91	Caenorhabditis briggsae	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_4269\|UniProtKB=E9GLR1	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_300421\|UniProtKB=E9G4R8	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_311056\|UniProtKB=E9FUH8	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_41461\|UniProtKB=E9FVD2	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG113361\|UniProtKB=T1EFR7	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g82503\|UniProtKB=A7RIG2	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG4552\|UniProtKB=B3S986	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG28382\|UniProtKB=B3S2Z3	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_25291\|UniProtKB=A9UYZ2	Monosiga brevicollis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_33990\|UniProtKB=F4NTG4	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_32150\|UniProtKB=F4P7T7	Batrachochytrium dendrobatidis	O
LEIMA\|EnsemblGenome=LMJF_29_0560\|UniProtKB=E9ADQ8	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.3.5130\|UniProtKB=Q580W2	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_29_0550\|UniProtKB=E9ADQ6	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.3.5140\|UniProtKB=Q580W1	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_29_0540\|UniProtKB=E9ADQ5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.3.5150\|UniProtKB=Q580W0	Trypanosoma brucei	O
ZOSMR\|Gene_ORFName=ZOSMA_163G00080\|UniProtKB=A0A0K9PU29	Zostera marina	O
MUSAM\|EnsemblGenome=Ma09_g29590\|UniProtKB=A0A804KQ41	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_007375mg\|UniProtKB=K3XZL4	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3010G134500\|UniProtKB=C5Z1R9	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb281480\|UniProtKB=B4FDU8	Zea mays	O
BRADI\|EnsemblGenome=BRADI_3g22650v3\|UniProtKB=I1I3F0	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0713180\|UniProtKB=A0A8I6YD31	Hordeum vulgare subsp. vulgare	O
NELNU\|Gene_ORFName=HUJ06_022549\|UniProtKB=A0A1U7ZCE5	Nelumbo nucifera	O
SPIOL\|Gene=LOC110783882\|UniProtKB=A0A9R0I7A4	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr03g0115271\|UniProtKB=A0A251T1Q4	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900495690\|UniProtKB=A0A9R1WSM9	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a009648mg\|UniProtKB=A0A022RYA3	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_20605\|UniProtKB=A0A1U8HCL8	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400012400\|UniProtKB=M1AX51	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc07g062750.3\|UniProtKB=A0A3Q7IAZ7	Solanum lycopersicum	O
TOBAC\|Gene=LOC107767783\|UniProtKB=A0A1S3XR51	Nicotiana tabacum	O
TOBAC\|Gene=LOC107813589\|UniProtKB=A0A1S4BZV0	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi19g00179\|UniProtKB=E0CSF1	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_F01176\|UniProtKB=A0A059BNI4	Eucalyptus grandis	O
BRACM\|EnsemblGenome=Bra027276\|UniProtKB=M4EER4	Brassica campestris	O
ARATH\|TAIR=locus=2083636\|UniProtKB=Q8W566	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107916937\|UniProtKB=A0A1U8KH67	Gossypium hirsutum	O
GOSHI\|Gene=LOC107939189\|UniProtKB=A0A1U8MMA7	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_031646\|UniProtKB=A0A061FF71	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g020417mg\|UniProtKB=A0A067EDH4	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_011G141300v3\|UniProtKB=B9I0H1	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_03G104800\|UniProtKB=A0A2C9W6B2	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0650270\|UniProtKB=B9SBA1	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_06G234800\|UniProtKB=I1KDP8	Glycine max	O
MEDTR\|EnsemblGenome=MTR_8g061030\|UniProtKB=G7LDQ1	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr02_21530\|UniProtKB=A0A2I4H248	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_4G628930\|UniProtKB=A0A0A0L4N2	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_4G173900\|UniProtKB=A0A251PM00	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_71144\|UniProtKB=D8QMK0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_87227\|UniProtKB=D8R7N1	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c27_5050\|UniProtKB=A0A2K1IAR0	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0005s0020\|UniProtKB=A0A2R6XQG0	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_004870100\|UniProtKB=A0A1Y1IDR4	Klebsormidium nitens	O