PANTHER Gene Information

Gene Symbol(s):

DNF2

Organism:

Saccharomyces cerevisiae

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Gene Name:

Phospholipid-transporting ATPase DNF2

Gene ID:

S000002500

Protein ID:

Q12675

Persistent Id:

PTN000642762

Alternate Ids:

ATC4_YEAST(UniProtKB-ID)	YEAST:G3O-29698-MON(BioCyc)
D6VS80(AltAccession)	6320298(GI)
851667(GeneID)	YDR093W(Ensembl)
CAA87668(EMBL-CDS)	NP_010378(refSeq)
YDR093W_mRNA(Ensembl_TRS)	Z47746(EMBL)
YDR093W(Ensembl_PRO)	DNF2(Symbol)
S000002500(SGD)	ATC4(Synonym)
7.6.2.1 {ECO:0000305\|PubMed:12631737, ECO:0000305\|PubMed:16847258, ECO:0000305\|PubMed:33060204, ECO:0000305\|PubMed:33320091}(EC)
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PANTHER Classification

PANTHER Family:	PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE (PTHR24092)
PANTHER Subfamily:	PHOSPHOLIPID-TRANSPORTING ATPASE DNF1-RELATED (PTHR24092:SF180)
PANTHER GO-slim Molecular Function:	ATPase-coupled intramembrane lipid transporter activity
PANTHER GO-slim Biological Process:	phospholipid translocation
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	primary active transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	magnesium ion binding, aminophospholipid flippase activity, ATP hydrolysis activity, ATP binding, phosphatidylethanolamine flippase activity, phosphatidylserine floppase activity, ATPase-coupled intramembrane lipid transporter activity, metal ion binding, phosphatidylcholine floppase activity, phosphatidylserine flippase activity, glycosylceramide flippase activity
GO BP Complete:	lipid transport, phospholipid translocation, establishment or maintenance of cell polarity, protein transport, ceramide translocation, phospholipid transport, endocytosis, aminophospholipid translocation
GO CC Complete:	cellular bud neck, membrane, endoplasmic reticulum, mating projection tip membrane, plasma membrane, cell periphery

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Transport of small molecules, Ion channel transport, Ion transport by P-type ATPases

Orthologs

ID	Organism	Type
EREGS\|EnsemblGenome=AGOS_AGR120C\|UniProtKB=Q74ZS8	Eremothecium gossypii	O
CANAL\|CGD=CAL0000175287\|UniProtKB=A0A1D8PJN3	Candida albicans	O
CANAL\|CGD=CAL0000173967\|UniProtKB=A0A1D8PMY6	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E17105g\|UniProtKB=Q6C5L2	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_C00495g\|UniProtKB=Q6CDH4	Yarrowia lipolytica	O
ASPFU\|EnsemblGenome=AFUA_6G02070\|UniProtKB=Q4WCQ6	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU07443\|UniProtKB=Q7SF11	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_07757\|UniProtKB=Q0UKF7	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC4F10.16c\|UniProtKB=O36028	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01731\|UniProtKB=B6JYR4	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC24B11.12c\|UniProtKB=Q09891	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_02897\|UniProtKB=B6K1G8	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNN01890\|UniProtKB=Q5K6X2	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_03293\|UniProtKB=A0A0D1DYK0	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_04678\|UniProtKB=E3K3S0	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_04671\|UniProtKB=E3K3R3	Puccinia graminis	O
CRYNJ\|EnsemblGenome=CND03980\|UniProtKB=Q5KI71	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10648\|UniProtKB=A0A0D1CPW3	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_07716\|UniProtKB=E3KDB9	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_19146\|UniProtKB=F4P0C4	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_9692\|UniProtKB=F4NWX1	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_14534\|UniProtKB=F4PCQ6	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_096620\|UniProtKB=C4LWH4	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_140130\|UniProtKB=C4M462	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_188210\|UniProtKB=C4M195	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_024120\|UniProtKB=C4MA58	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_174280\|UniProtKB=B1N3G4	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0286891\|UniProtKB=Q54L55	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_49817\|UniProtKB=F0ZVJ7	Dictyostelium purpureum	O
PLAF7\|EnsemblGenome=PF3D7_1468600\|UniProtKB=Q8IKF1	Plasmodium falciparum	O
PHYRM\|Gene=H3HAP9_PHYRM\|UniProtKB=H3HAP9	Phytophthora ramorum	O
PHYRM\|Gene=H3GFP8_PHYRM\|UniProtKB=H3GFP8	Phytophthora ramorum	O
PHYRM\|Gene=H3GP37_PHYRM\|UniProtKB=H3GP37	Phytophthora ramorum	O
PHYRM\|Gene=H3GXQ6_PHYRM\|UniProtKB=H3GXQ6	Phytophthora ramorum	O
PHYRM\|Gene=H3GVQ5_PHYRM\|UniProtKB=H3GVQ5	Phytophthora ramorum	O
PHYRM\|Gene=H3GNA3_PHYRM\|UniProtKB=H3GNA3	Phytophthora ramorum	O
AMBTC\|EnsemblGenome=AMTR_s00133p00030750\|UniProtKB=W1P9V6	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_4G00490\|UniProtKB=A0A0K9NYF9	Zostera marina	O
MUSAM\|EnsemblGenome=Ma08_g32180\|UniProtKB=A0A804KD68	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma07_g17810\|UniProtKB=A0A804JWW9	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_033945mg\|UniProtKB=K4A4Z1	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G251200\|UniProtKB=A0A1B6QKW3	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb048220\|UniProtKB=A0A1D6KVF4	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb223160\|UniProtKB=A0A804PBQ3	Zea mays	O
BRADI\|EnsemblGenome=BRADI_3g26400v3\|UniProtKB=A0A2K2CZC7	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0034380\|UniProtKB=A0A8I7B2U2	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS1B02G154200\|UniProtKB=A0A3B5YUT3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G132600\|UniProtKB=A0A3B5XXE7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G135500\|UniProtKB=A0A3B5ZS17	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_009961\|UniProtKB=A0A1U8B7E1	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_005385\|UniProtKB=A0A1U8A204	Nelumbo nucifera	O
SPIOL\|Gene=LOC110789544\|UniProtKB=A0A9R0JXB9	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0562001\|UniProtKB=A0A251T5Q1	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400160620\|UniProtKB=A0A9R1VSR3	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0317301\|UniProtKB=A0A251U4G1	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C800453080\|UniProtKB=A0A9R1UVR2	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a000321mg\|UniProtKB=A0A022Q5I8	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_01994\|UniProtKB=A0A1U8GCQ9	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc01g011093.1\|UniProtKB=A0A3Q7EAE6	Solanum lycopersicum	O
TOBAC\|Gene=LOC107760557\|UniProtKB=A0A1S3X2F9	Nicotiana tabacum	O
TOBAC\|Gene=LOC107760085\|UniProtKB=A0A1S3X195	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_27427\|UniProtKB=A0A1U8EVI0	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc05g006640.3\|UniProtKB=A0A3Q7GD55	Solanum lycopersicum	O
TOBAC\|Gene=LOC107759414\|UniProtKB=A0A1S3WZ65	Nicotiana tabacum	O
TOBAC\|Gene=LOC107828611\|UniProtKB=A0A1S4DDD2	Nicotiana tabacum	O
EUCGR\|EnsemblGenome=EUGRSUZ_B03390\|UniProtKB=A0A059D981	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_A09P65080.1\|UniProtKB=A0A078HDI4	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00124937001\|UniProtKB=A0A078F7U6	Brassica napus	O
BRACM\|EnsemblGenome=Bra031711\|UniProtKB=M4ESD3	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00037202001\|UniProtKB=A0A078GQ08	Brassica napus	O
BRACM\|EnsemblGenome=Bra017897\|UniProtKB=M4DN10	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A01P28860.1\|UniProtKB=A0A078GGN5	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00054919001\|UniProtKB=A0A078H810	Brassica napus	O
BRACM\|EnsemblGenome=Bra035422\|UniProtKB=M4F2X2	Brassica campestris	O
ARATH\|TAIR=locus=2025961\|UniProtKB=Q9XIE6	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107886595\|UniProtKB=A0A1U8HJ38	Gossypium hirsutum	O
GOSHI\|Gene=LOC107959952\|UniProtKB=A0A1U8PMQ1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107903682\|UniProtKB=A0A1U8JAQ1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107934523\|UniProtKB=A0A1U8M6M1	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_010087\|UniProtKB=A0A061E5H9	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g0009122mg\|UniProtKB=A0A067H588	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_008G191400v3\|UniProtKB=A0A2K1ZJV2	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_010G039900v3\|UniProtKB=A0A2K1YNI2	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_05G094400\|UniProtKB=A0A2C9VX78	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_01G193500\|UniProtKB=A0A2C9WM10	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0699240\|UniProtKB=B9S2G0	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_08G293900\|UniProtKB=I1KXN1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_18G129200\|UniProtKB=K7MRR2	Glycine max	O
MEDTR\|EnsemblGenome=MTR_5g037210\|UniProtKB=G7K711	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr16_10820\|UniProtKB=A0A2I4EI73	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_5G604040\|UniProtKB=A0A0A0KSH4	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G263700\|UniProtKB=A0A251R3M4	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_164122\|UniProtKB=D8QMQ3	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_168751\|UniProtKB=D8R7H0	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c7_11320\|UniProtKB=A0A2K1KBB8	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0020s0113\|UniProtKB=A0A2R6XED0	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001500140\|UniProtKB=A0A1Y1HXV0	Klebsormidium nitens	O