PANTHER Gene Information   
Gene Symbol(s): E2F2
Organism: Homo sapiens
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Gene Name: Transcription factor E2F2
Gene ID: HGNC:3114
Protein ID: Q14209
Enhancers: View enhancers for HUMAN|HGNC=3114|UniProtKB=Q14209
Genetic Variant Annotation: Annoq
Persistent Id: PTN002486111
Alternate Ids:
B2R9W1(AltAccession) ENSG00000282899(Ensembl)
AAM54044(EMBL-CDS) 28373876(GI)
ENST00000634683(Ensembl_TRS) AL021154(EMBL)
E2F2(Synonym) E2F2(Symbol)
E2F2_HUMAN(UniProtKB-ID) CHEMBL4630726(ChEMBL)
600426(MIM) NP_004082(refSeq)
HGNC:3114(HGNC) ENSP00000355249(Ensembl_PRO)
1870(GeneID)
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PANTHER Classification
PANTHER Family: TRANSCRIPTION FACTOR E2F (PTHR12081)
PANTHER Subfamily: TRANSCRIPTION FACTOR E2F2 (PTHR12081:SF50)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: RNA polymerase II transcription regulator complex
PANTHER protein class: winged helix/forkhead transcription factor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: DNA binding, DNA-binding transcription factor activity, protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific DNA binding, protein dimerization activity, sequence-specific double-stranded DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete: negative regulation of sprouting angiogenesis, intrinsic apoptotic signaling pathway by p53 class mediator, regulation of DNA-templated transcription, regulation of cell cycle, positive regulation of transcription by RNA polymerase II, lens fiber cell apoptotic process, transcription initiation at RNA polymerase II promoter, regulation of transcription by RNA polymerase II
GO CC Complete: Rb-E2F complex, RNA polymerase II transcription regulator complex, chromatin, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Cellular Senescence, Mitotic G1 phase and G1/S transition, Cell Cycle, Mitotic, Oxidative Stress Induced Senescence, Cell Cycle, Cellular responses to stress, Cyclin D associated events in G1, Cellular responses to stimuli, Aberrant regulation of mitotic cell cycle due to RB1 defects, Disease, Defective binding of RB1 mutants to E2F1,(E2F2, E2F3), Oncogene Induced Senescence, Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects, Diseases of mitotic cell cycle, G1 Phase

Orthologs