PANTHER Gene Information   
Gene Symbol(s): ERCC3
Organism: Bos taurus
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Gene Name: General transcription and DNA repair factor IIH helicase subunit XPB
Gene ID: ENSBTAG00000020777
Protein ID: Q1RMT1
Persistent Id: PTN007500885
Alternate Ids:
3.6.4.12(EC) NP_001039453(refSeq)
ENSBTAG00000020777(Ensembl) 122134582(GI)
BC114729(EMBL) AAI14730(EMBL-CDS)
ENSBTAP00000027687(Ensembl_PRO) ENSBTAT00000027687(Ensembl_TRS)
ERCC3(Symbol) 507984(GeneID)
ERCC3_BOVIN(UniProtKB-ID) ERCC3(Synonym)
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PANTHER Classification
PANTHER Family: RAD25/XP-B DNA REPAIR HELICASE (PTHR11274)
PANTHER Subfamily: GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB (PTHR11274:SF0)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class: DNA helicase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP hydrolysis activity, double-stranded DNA helicase activity, four-way junction helicase activity, forked DNA-dependent helicase activity, 3'-5' DNA helicase activity, cohesin loader activity, DNA binding, ATP binding, DNA clamp loader activity, ATP-dependent H2AZ histone chaperone activity, protein binding, promoter-specific chromatin binding, ATP-dependent H3-H4 histone complex chaperone activity, single-stranded 3'-5' DNA helicase activity, chromatin extrusion motor activity, isomerase activity
GO BP Complete: DNA repair, nucleotide-excision repair, DNA duplex unwinding, regulation of mitotic cell cycle phase transition, UV protection, transcription-coupled nucleotide-excision repair, protein localization, nucleotide-excision repair, transcription by RNA polymerase II, response to UV, embryonic organ development, DNA topological change, transcription initiation at RNA polymerase II promoter, response to oxidative stress, chromatin remodeling, apoptotic process, positive regulation of apoptotic process, chromatin looping, hair cell differentiation
GO CC Complete: transcription preinitiation complex, transcription factor TFIID complex, transcription factor TFIIH core complex, transcription factor TFIIH holo complex, nucleotide-excision repair factor 3 complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: RNA Pol II CTD phosphorylation and interaction with CE, Gene expression (Transcription), RNA Polymerase II Transcription Initiation And Promoter Clearance, RNA Polymerase I Transcription, RNA Polymerase I Transcription Termination, Dual incision in TC-NER, DNA Repair, RNA Polymerase I Promoter Escape, Gap-filling DNA repair synthesis and ligation in TC-NER, Transcriptional Regulation by TP53, mRNA Capping, TP53 Regulates Transcription of DNA Repair Genes, Dual Incision in GG-NER, Generic Transcription Pathway, Metabolism of RNA, Transcription-Coupled Nucleotide Excision Repair (TC-NER), RNA Polymerase II Transcription, Formation of the Early Elongation Complex, Formation of TC-NER Pre-Incision Complex, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening, RNA Polymerase I Promoter Clearance, RNA Polymerase II Promoter Escape, RNA Polymerase II Transcription Initiation, RNA Polymerase I Transcription Initiation, RNA Polymerase II Transcription Elongation, Nucleotide Excision Repair, Formation of Incision Complex in GG-NER, Global Genome Nucleotide Excision Repair (GG-NER), RNA Polymerase II Pre-transcription Events

Orthologs