PANTHER Gene Information

Gene Symbol(s):

spc-1

Organism:

Caenorhabditis elegans

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Gene Name:

Spectrin alpha chain

Gene ID:

WBGene00004951

Protein ID:

Q21408

Persistent Id:

PTN000747295

Alternate Ids:

180603(GeneID)	CCD64607(EMBL-CDS)
CE46456(WormBase_PRO)	WBGene00004951(WormBase)
Q21408(Synonym)	K10B3.10b(WormBase_TRS)
WBGene00004951(Ensembl)	BX284606(EMBL)
NM_001270071(refSeq)	373218976(GI)
Q21408_CAEEL(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN (PTHR11915)
PANTHER Subfamily:	SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1-RELATED (PTHR11915:SF422)
PANTHER GO-slim Molecular Function:	actin filament binding
PANTHER GO-slim Biological Process:	actin cytoskeleton organization
PANTHER GO-slim Cellular Component:	cell junction cortical actin cytoskeleton cell projection plasma membrane
PANTHER protein class:	actin or actin-binding cytoskeletal protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	actin filament binding, calmodulin binding, metal ion binding, calcium ion binding
GO BP Complete:	regulation of locomotion, actin filament capping, nematode larval development, embryonic body morphogenesis, actin cytoskeleton organization, positive regulation of multicellular organism growth
GO CC Complete:	cytoskeleton, cytoplasm, cell junction, intracellular non-membrane-bounded organelle, cell projection, plasma membrane, cortical actin cytoskeleton

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

MAPK1/MAPK3 signaling, Signal Transduction, Caspase-mediated cleavage of cytoskeletal proteins, Innate Immune System, Signaling by Rho GTPases, Nervous system development, Developmental Biology, Vesicle-mediated transport, RHOV GTPase cycle, Membrane Trafficking, COPI-mediated anterograde transport, RHOU GTPase cycle, Apoptotic execution phase, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Asparagine N-linked glycosylation, Axon guidance, Immune System, RAF/MAP kinase cascade, Apoptotic cleavage of cellular proteins, NCAM signaling for neurite out-growth, Transport to the Golgi and subsequent modification, Apoptosis, MAPK family signaling cascades, Programmed Cell Death, Neutrophil degranulation, ER to Golgi Anterograde Transport, RHO GTPase cycle, Post-translational protein modification, Metabolism of proteins

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11272\|UniProtKB=P02549	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001510.6\|UniProtKB=H2Q0C2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000508.3\|UniProtKB=G3QE19	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000730.4\|UniProtKB=F7HJP2	Macaca mulatta	O
MOUSE\|MGI=MGI=98385\|UniProtKB=P08032	Mus musculus	O
RAT\|RGD=1305194\|UniProtKB=D4A678	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000000888.7\|UniProtKB=F1MMQ8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000006431.5\|UniProtKB=A0A5G2R924	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000021886.4\|UniProtKB=F6ZK25	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000046674.2\|UniProtKB=A0A337S3L8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845016151.1\|UniProtKB=A0A8I3P3Z7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000010331.4\|UniProtKB=F6S9F7	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000013338.2\|UniProtKB=A0A6I8P3N0	Ornithorhynchus anatinus	O
HUMAN\|HGNC=11273\|UniProtKB=Q13813	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000021433.7\|UniProtKB=H2R2T8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007615.3\|UniProtKB=G3QXD1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009327.4\|UniProtKB=A0A5K1TXE9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98386\|UniProtKB=P16546	Mus musculus	LDO
RAT\|RGD=621714\|UniProtKB=P16086	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015327.6\|UniProtKB=E1BFB0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000005654.5\|UniProtKB=A0A286ZXS0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000021297.4\|UniProtKB=A0A3Q2LB26	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005846.6\|UniProtKB=A0A2I2UB74	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845027492.1\|UniProtKB=A0A8I3Q1F4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006252.4\|UniProtKB=F6TSC9	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011986.3\|UniProtKB=F7AQ59	Ornithorhynchus anatinus	LDO
CHICK\|Gene=SPTAN1\|UniProtKB=P07751	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010028556.1\|UniProtKB=A0A8V1AH25	Gallus gallus	LDO
XENLA\|Gene=sptan1.S\|UniProtKB=A0A8J1LPQ3	Xenopus laevis	O
XENLA\|Gene=sptan1.L\|UniProtKB=A0A8J1LHS5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-986854\|UniProtKB=A0A6I8SVI1	Xenopus tropicalis	LDO
DANRE\|ZFIN=ZDB-GENE-051113-60\|UniProtKB=A3FG33	Danio rerio	O
DANRE\|Gene=spna2\|UniProtKB=A0A8M9PQF2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005929.1\|UniProtKB=W5MFP4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000019314.1\|UniProtKB=H2XRN5	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118423381\|UniProtKB=A0A9J7N255	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421631\|UniProtKB=A0A9J7LL94	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC582631\|UniProtKB=A0A7M7SY23	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC580822\|UniProtKB=A0A7M7PL99	Strongylocentrotus purpuratus	LDO
CAEBR\|Gene_ORFName=CBG14139\|UniProtKB=A8XJE3	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00112003\|UniProtKB=A0A2A6CFM8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0250789\|UniProtKB=P13395	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP006686\|UniProtKB=Q7Q515	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000749\|UniProtKB=D6W8J4	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_206384\|UniProtKB=E9FW64	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW000012\|UniProtKB=B7P1U8	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG156368\|UniProtKB=T1ELU5	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g238120\|UniProtKB=A7RGP6	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG59818\|UniProtKB=B3S6I6	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_14504\|UniProtKB=A9UST9	Monosiga brevicollis	LDO
YARLI\|EnsemblGenome=YALI0_F07601g\|UniProtKB=Q6C2I6	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_07707\|UniProtKB=Q5AVH3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G08300\|UniProtKB=Q4WUF8	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU06429\|UniProtKB=Q7RYY6	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_00266\|UniProtKB=A7E4P4	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_09258\|UniProtKB=Q0UG56	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC15A10.08\|UniProtKB=O13728	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04621\|UniProtKB=B6K7B3	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNC06000\|UniProtKB=Q5KJM5	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_04312\|UniProtKB=A0A0D1DXH0	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_12436\|UniProtKB=E3KQA5	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_20161\|UniProtKB=F4P7B2	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0287291\|UniProtKB=O76329	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0268632\|UniProtKB=P05095	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_47922\|UniProtKB=F0ZLZ7	Dictyostelium purpureum	O