PANTHER Gene Information

Gene Symbol(s):

mans-3

Organism:

Caenorhabditis elegans

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Gene Name:

alpha-1,2-Mannosidase

Gene ID:

WBGene00020197

Protein ID:

Q22120

Persistent Id:

PTN000201733

Alternate Ids:

Q22120(Synonym)	T03G11(WormBase_TRS)
NP_508877(refSeq)	Q22120_CAEEL(UniProtKB-ID)
WBGene00020197(Ensembl)	351061053(GI)
BX284606(EMBL)	CCD68813(EMBL-CDS)
WBGene00020197(WormBase)	180787(GeneID)
CE29462(WormBase_PRO)
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PANTHER Classification

PANTHER Family:	MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED (PTHR11742)
PANTHER Subfamily:	ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE (PTHR11742:SF55)
PANTHER GO-slim Molecular Function:	hydrolase activity, hydrolyzing O-glycosyl compounds
PANTHER GO-slim Biological Process:	glycoprotein metabolic process response to oxygen-containing compound carbohydrate derivative catabolic process protein modification process ERAD pathway
PANTHER GO-slim Cellular Component:	endoplasmic reticulum membrane
PANTHER protein class:	protein modifying enzyme

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	alpha-mannosidase activity, metal ion binding, calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, hydrolase activity, acting on glycosyl bonds
GO BP Complete:	carbohydrate metabolic process, ERAD pathway
GO CC Complete:	membrane, endoplasmic reticulum

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6823\|UniProtKB=Q9UKM7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000021591.5\|UniProtKB=H2QY80	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001613.3\|UniProtKB=G3SHK3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000008036.4\|UniProtKB=F7GR74	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2684954\|UniProtKB=A2AJ15	Mus musculus	LDO
RAT\|RGD=1563595\|UniProtKB=B2GUY0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000046775.2\|UniProtKB=G3MXQ8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000039830.3\|UniProtKB=A0A287A7G4	Sus scrofa	LDO
PIG\|Ensembl=ENSSSCG00000027526.4\|UniProtKB=I3LIM8	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000042440.2\|UniProtKB=A0A337S0M9	Felis catus	O
FELCA\|Ensembl=ENSFCAG00000038731.3\|UniProtKB=A0A2I2V1B7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845024757.1\|UniProtKB=A0A8I3Q4Z8	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845024994.1\|UniProtKB=A0A8I3PTB7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017244.4\|UniProtKB=F6TLC5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014254.2\|UniProtKB=F6VLK7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010028049.1\|UniProtKB=A0A8V1ABV1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013155.4\|UniProtKB=H9GJP1	Anolis carolinensis	LDO
XENLA\|Gene=man1b1.L\|UniProtKB=Q68FC2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5873781\|UniProtKB=B0JZF2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000013901.2\|UniProtKB=H2MFQ1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000017744.2\|UniProtKB=H2MTU9	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-091116-34\|UniProtKB=E7F4N5	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-070705-482\|UniProtKB=A5WWD5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001522.1\|UniProtKB=W5M044	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006932.3\|UniProtKB=F6VNW9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118420800\|UniProtKB=A0A9J7LIW3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC592701\|UniProtKB=A0A7M7NR34	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC115919045\|UniProtKB=A0A7M7PMS2	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00035057\|UniProtKB=A8XKB3	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00109650\|UniProtKB=A0A2A6B4N9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0039634\|UniProtKB=Q9VAP8	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP003884\|UniProtKB=F5HIW5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002991\|UniProtKB=D6WGJ6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_194674\|UniProtKB=E9G8U4	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW012200\|UniProtKB=B7QCL8	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG178867\|UniProtKB=T1FDU3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG193110\|UniProtKB=T1FUM7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG113976\|UniProtKB=T1EFX8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g13029\|UniProtKB=A7T0F0	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG53127\|UniProtKB=B3RND6	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_13888\|UniProtKB=A9UNJ2	Monosiga brevicollis	LDO
YEAST\|SGD=S000004047\|UniProtKB=Q12205	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ACR213W\|UniProtKB=Q75BQ8	Eremothecium gossypii	O
YARLI\|EnsemblGenome=YALI0_D20174g\|UniProtKB=Q6C8F1	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_02045\|UniProtKB=Q5BBN5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G10070\|UniProtKB=Q4WPQ3	Neosartorya fumigata	O
SCLS1\|EnsemblGenome=SS1G_09338\|UniProtKB=A7EVI0	Sclerotinia sclerotiorum	O
SCLS1\|Gene_ORFName=SS1G_09671\|UniProtKB=A7EWG2	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_13704\|UniProtKB=Q0U3G0	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_03566\|UniProtKB=G5EB12	Emericella nidulans	O
NEUCR\|EnsemblGenome=NCU03134\|UniProtKB=Q7SDV6	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU05836\|UniProtKB=Q7S5K7	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_09104\|UniProtKB=A7EUU6	Sclerotinia sclerotiorum	O
NEUCR\|EnsemblGenome=NCU01059\|UniProtKB=Q1K8A8	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_14200\|UniProtKB=Q0U236	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_03733\|UniProtKB=Q5B6U7	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G12360\|UniProtKB=Q4WLT8	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU09028\|UniProtKB=Q7S2U7	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_12698\|UniProtKB=Q0U6B6	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_06721\|UniProtKB=Q0UNE3	Phaeosphaeria nodorum	O
NEUCR\|EnsemblGenome=NCU02235\|UniProtKB=V5IMQ2	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_14236\|UniProtKB=A7F9F5	Sclerotinia sclerotiorum	O
SCLS1\|Gene_ORFName=SS1G_07919\|UniProtKB=A7ERG5	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_12268\|UniProtKB=Q0U7J6	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNG03330\|UniProtKB=Q5KDN4	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10494\|UniProtKB=A0A0D1DV47	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_03556\|UniProtKB=E3JZX5	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_20955\|UniProtKB=H6QQ09	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_11419\|UniProtKB=E3KLQ1	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_11420\|UniProtKB=E3KLQ2	Puccinia graminis	O
EMENI\|EnsemblGenome=ANIA_00787\|UniProtKB=Q5BF93	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G14560\|UniProtKB=Q4WRZ5	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU07067\|UniProtKB=Q7S6F6	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_04468\|UniProtKB=A7EGM6	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_12593\|UniProtKB=Q0U6M1	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_11750\|UniProtKB=Q0U914	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_01957\|UniProtKB=A0A0D1E532	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_21538\|UniProtKB=H6QRR6	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_09376\|UniProtKB=E3KH88	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_09507\|UniProtKB=E3KHL9	Puccinia graminis	O
YEAST\|SGD=S000003892\|UniProtKB=P32906	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER165W\|UniProtKB=Q756T8	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000181785\|UniProtKB=A0A1D8PD38	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D17424g\|UniProtKB=Q6C8S3	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00551\|UniProtKB=Q5BFX9	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_05748\|UniProtKB=Q5B132	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G06790\|UniProtKB=Q4WND0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU02778\|UniProtKB=Q7SE16	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_04513\|UniProtKB=A7EGS1	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03652\|UniProtKB=Q0UX62	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC2E1P5.01c\|UniProtKB=Q9P7C3	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03032\|UniProtKB=B6K350	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNE04550\|UniProtKB=Q5KG79	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02227\|UniProtKB=A0A0D1CT53	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_11422\|UniProtKB=E3KLQ4	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_14908\|UniProtKB=E3KXK5	Puccinia graminis	LDO
TRIV3\|Gene_ORFName=TVAG_296340\|UniProtKB=A2F782	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_345080\|UniProtKB=A2G688	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_059860\|UniProtKB=A2FHY9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_447400\|UniProtKB=A2DS11	Trichomonas vaginalis	LDO
PHYRM\|Gene=H3GLG6_PHYRM\|UniProtKB=H3GLG6	Phytophthora ramorum	O
PHYRM\|Gene=H3G698_PHYRM\|UniProtKB=H3G698	Phytophthora ramorum	LDO
PHYRM\|Gene=H3G697_PHYRM\|UniProtKB=H3G697	Phytophthora ramorum	LDO
PHYRM\|Gene=H3G775_PHYRM\|UniProtKB=H3G775	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_07g336600v5\|UniProtKB=A0A2K3DK84	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00141p00108250\|UniProtKB=W1PIT9	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_85G00270\|UniProtKB=A0A0K9NN05	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma10_g14420\|UniProtKB=A0A804KW48	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma06_g15930\|UniProtKB=A0A804JGR3	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_021445mg\|UniProtKB=K3Z4H7	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3009G077600\|UniProtKB=C5YUN6	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb350710\|UniProtKB=K7UWA5	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os05g0209100\|UniProtKB=Q0DK00	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g32570v3\|UniProtKB=I1HKX3	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0031450\|UniProtKB=M0WEB1	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G145500\|UniProtKB=A0A3B5YUF4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G126300\|UniProtKB=A0A3B5XX54	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G127200\|UniProtKB=A0A3B5ZR71	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_008179\|UniProtKB=A0A1U8BQR7	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110794113\|UniProtKB=A0A9R0K1A4	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0173451\|UniProtKB=A0A251UZW2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0695381\|UniProtKB=A0A251S8Y7	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700353420\|UniProtKB=A0A9R1X5F9	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a002872mg\|UniProtKB=A0A022R171	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_03612\|UniProtKB=A0A1U8FJR2	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc02g070520.3\|UniProtKB=A0A3Q7F1Z6	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107782104\|UniProtKB=A0A1S3Z244	Nicotiana tabacum	O
TOBAC\|Gene=LOC107783782\|UniProtKB=A0A1S3Z7V3	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi10g00778\|UniProtKB=F6HLR4	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_D00298\|UniProtKB=A0A059CDD2	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A09P36520.1\|UniProtKB=A0A078GIJ8	Brassica napus	O
BRACM\|EnsemblGenome=Bra032351\|UniProtKB=M4EU69	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C03P76300.1\|UniProtKB=A0A078HBX2	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra010804\|UniProtKB=M4D2V1	Brassica campestris	LDO
ARATH\|TAIR=locus=2198299\|UniProtKB=Q93Y37	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107960260\|UniProtKB=A0A1U8PLI4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107905885\|UniProtKB=A0A1U8JHL8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107958416\|UniProtKB=A0A1U8PH95	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_029492\|UniProtKB=A0A061GCZ1	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_004G132300v3\|UniProtKB=A0A2K2ATZ8	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_17G069200\|UniProtKB=A0A2C9U5K4	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_15G120800\|UniProtKB=A0A2C9UF53	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0632950\|UniProtKB=B9S125	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_13G217900\|UniProtKB=I1M1F2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_15G094500\|UniProtKB=I1MF37	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g019520\|UniProtKB=G7IPW7	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr03_14610\|UniProtKB=A0A2I4EDM2	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G523340\|UniProtKB=A0A0A0KLY9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G080100\|UniProtKB=M5X2H5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_168485\|UniProtKB=D8R549	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_176646\|UniProtKB=D8S3V6	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c10_9960\|UniProtKB=A0A2K1JYF8	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0010s0002\|UniProtKB=A0A2R6XKF8	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000890230\|UniProtKB=A0A1Y1HSY5	Klebsormidium nitens	LDO