PANTHER Gene Information

Gene Symbol(s):

CD44

Organism:

Canis lupus familiaris

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Gene Name:

CD44 antigen (Fragment)

Gene ID:

CD44

Protein ID:

Q28284

Persistent Id:

PTN004140304

Alternate Ids:

473227(GI)	Hermes antigen(Synonym)
CAA81630(EMBL-CDS)	Z27115(EMBL)
CD44_CANLF(UniProtKB-ID)	CD44(Symbol)
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PANTHER Classification

PANTHER Family:	HYALURONAN RECEPTOR (PTHR10225)
PANTHER Subfamily:	CD44 ANTIGEN (PTHR10225:SF6)
PANTHER GO-slim Molecular Function:	cytokine receptor activity glycosaminoglycan binding
PANTHER GO-slim Biological Process:	cell adhesion inflammatory response positive regulation of ERK1 and ERK2 cascade
PANTHER GO-slim Cellular Component:	basolateral plasma membrane receptor complex
PANTHER protein class:	transmembrane signal receptor

Pathway Categories:

Alzheimer disease-presenilin pathway

CD44 transmembrane fragment

Alzheimer disease-presenilin pathway

Cell surface glycoprotein 44

Alzheimer disease-presenilin pathway

CD44 C-terminal fragment

Alzheimer disease-presenilin pathway

CD44 N-terminal fragment

Alzheimer disease-presenilin pathway

CD44 intracellular fragment

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	transmembrane signaling receptor activity, hyaluronic acid binding, cytokine receptor activity
GO BP Complete:	wound healing, spreading of cells, inflammatory response, cytokine-mediated signaling pathway, positive regulation of ERK1 and ERK2 cascade, regulation of lamellipodium morphogenesis, cell adhesion
GO CC Complete:	microvillus, macrophage migration inhibitory factor receptor complex, extracellular region, basolateral plasma membrane, cell projection, plasma membrane, apical plasma membrane, lamellipodium membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=1681\|UniProtKB=P16070	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000003501.6\|UniProtKB=A0A2I3TNC3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000851.4\|UniProtKB=A0A2I2ZB03	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000004327.4\|UniProtKB=F6ZDZ8	Macaca mulatta	O
MOUSE\|MGI=MGI=88338\|UniProtKB=P15379	Mus musculus	O
RAT\|RGD=2307\|UniProtKB=P26051	Rattus norvegicus	O
BOVIN\|Gene=CD44\|UniProtKB=Q29423	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000011578.6\|UniProtKB=F1MQT9	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000013297.6\|UniProtKB=F1SGT4	Sus scrofa	O
HORSE\|Gene=CD44\|UniProtKB=Q05078	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000010267.4\|UniProtKB=A0A3Q2HEJ5	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005887.6\|UniProtKB=A0A337SMK2	Felis catus	O
MONDO\|Ensembl=ENSMODG00000045292.1\|UniProtKB=A0A5F8GLJ6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007392.4\|UniProtKB=A0A6I8NCF4	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010024974.1\|UniProtKB=A0A8V1A8P7	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000044506.1\|UniProtKB=A0A803U1D1	Anolis carolinensis	O
XENLA\|Gene=cd44.L\|UniProtKB=A0A8J0UT55	Xenopus laevis	O
XENLA\|Gene=cd44.S\|UniProtKB=A0A1L8GE56	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-487547\|UniProtKB=A0A803KIY4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000029763.1\|UniProtKB=A0A3B3HCS6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-110429-1\|UniProtKB=E7F6T0	Danio rerio	O
DANRE\|Gene=cd44b\|UniProtKB=A0A8M6YYL8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000001378.1\|UniProtKB=W5LZK3	lepisosteus oculatus	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g196789\|UniProtKB=A7RGE0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g210422\|UniProtKB=A7SD49	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g210423\|UniProtKB=A7SD50	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g210418\|UniProtKB=A7SD47	Nematostella vectensis	O