PANTHER Gene Information

Gene Symbol(s):

USP2

Organism:

Bos taurus

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Gene Name:

Ubiquitin carboxyl-terminal hydrolase 2

Gene ID:

ENSBTAG00000009749

Protein ID:

Q2KHV7

Persistent Id:

PTN007698335

Alternate Ids:

USP2(Symbol)	Ubiquitin-specific-processing protease 2(Synonym)
522980(GeneID)	ENSBTAP00000012857(Ensembl_PRO)
BC112866(EMBL)	ENSBTAT00000012857(Ensembl_TRS)
ENSBTAG00000009749(Ensembl)	AAI12867(EMBL-CDS)
3.4.19.12(EC)	114053169(GI)
UBP2_BOVIN(UniProtKB-ID)	NM_001046263(refSeq)
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PANTHER Classification

PANTHER Family:	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE (PTHR21646)
PANTHER Subfamily:	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2 (PTHR21646:SF17)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	cysteine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	cysteine-type deubiquitinase activity, metal ion binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, muscle organ development, protein deubiquitination, circadian regulation of gene expression, locomotor rhythm, proteolysis, entrainment of circadian clock by photoperiod, circadian behavior, protein stabilization, positive regulation of mitotic cell cycle
GO CC Complete:	perinuclear region of cytoplasm, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

TNFR1-induced proapoptotic signaling, Regulation of TNFR1 signaling, TNF signaling, Signal Transduction, TNFR1-induced NF-kappa-B signaling pathway, Death Receptor Signaling

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12618\|UniProtKB=O75604	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004384.6\|UniProtKB=H2Q4Y6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000005083.3\|UniProtKB=G3QQW0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000008921.4\|UniProtKB=F7DHM3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1858178\|UniProtKB=O88623	Mus musculus	LDO
RAT\|RGD=621073\|UniProtKB=Q5U349	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000015120.5\|UniProtKB=I3LI16	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019869.4\|UniProtKB=F7BTM1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000000980.6\|UniProtKB=A0A2I2URI0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014492.1\|UniProtKB=A0A8I3NP69	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000013213.3\|UniProtKB=F7EVY9	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000004771.4\|UniProtKB=A0A6I8MXA2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010026090.1\|UniProtKB=A0A8V1A7R4	Gallus gallus	LDO
CHICK\|Gene=USP2\|UniProtKB=O57429	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000027046.3\|UniProtKB=A0A803TZ69	Anolis carolinensis	LDO
XENLA\|Gene=usp2.S\|UniProtKB=A0A1L8FFZ3	Xenopus laevis	LDO
XENLA\|Gene=usp2.L\|UniProtKB=A0A1L8FLG3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-962796\|UniProtKB=A0A6I8SRE1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000014803.2\|UniProtKB=H2MIS5	Oryzias latipes	O
DANRE\|Gene=usp2b\|UniProtKB=A0A8M3AST8	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000009912.2\|UniProtKB=H2M1Z7	Oryzias latipes	LDO
DANRE\|Gene=usp2a\|UniProtKB=A0A8M9QLD6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001706.1\|UniProtKB=W5M0S7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009000.3\|UniProtKB=F6UBJ3	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_75955\|UniProtKB=C3YPQ5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427382\|UniProtKB=A0A9J7N803	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00000874\|UniProtKB=Q8WT44	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG21788\|UniProtKB=A8Y0H4	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG09021\|UniProtKB=A8X800	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00275050\|UniProtKB=A0A2A6BP83	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0031187\|UniProtKB=Q8IQ27	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001052\|UniProtKB=F5HLW2	Anopheles gambiae	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_307972\|UniProtKB=E9H578	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW010054\|UniProtKB=B7Q1R2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG171628\|UniProtKB=T1F4H3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG88096\|UniProtKB=T1G6Y5	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g240984\|UniProtKB=A7RVJ3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g124482\|UniProtKB=A7SN67	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG33494\|UniProtKB=B3SCT1	Trichoplax adhaerens	LDO
EMENI\|EnsemblGenome=ANIA_02072\|UniProtKB=Q5BBK8	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G04720\|UniProtKB=Q4WHN9	Neosartorya fumigata	LDO
PHANO\|EnsemblGenome=SNOG_13165\|UniProtKB=Q0U4Z9	Phaeosphaeria nodorum	LDO
ENTH1\|EnsemblGenome=EHI_009430\|UniProtKB=C4LZ20	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0274207\|UniProtKB=Q86KB3	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0268872\|UniProtKB=Q55EJ1	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_156322\|UniProtKB=F0ZWA4	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_32_2910\|UniProtKB=Q9U1E5	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.7760\|UniProtKB=Q381H6	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_197680\|UniProtKB=A2EJI5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_195780\|UniProtKB=A2ETL7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_107900\|UniProtKB=A2F7W0	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1414700\|UniProtKB=Q8ILU9	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_0726500\|UniProtKB=Q8IBJ1	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00004612001\|UniProtKB=A0BDA1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032822001\|UniProtKB=A0BWQ3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009669001\|UniProtKB=A0CRD7	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00008347001\|UniProtKB=A0CM51	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00006350001\|UniProtKB=A0C4Y4	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_4243\|UniProtKB=B8C1B7	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GLU7_PHYRM\|UniProtKB=H3GLU7	Phytophthora ramorum	LDO
MUSAM\|EnsemblGenome=Ma09_g08450\|UniProtKB=A0A804KHC9	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_009913mg\|UniProtKB=K3Y6S2	Setaria italica	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0168270\|UniProtKB=A0A8I6XA42	Hordeum vulgare subsp. vulgare	LDO
SPIOL\|Gene=LOC110786268\|UniProtKB=A0A9R0IC13	Spinacia oleracea	LDO
LACSA\|Gene_ORFName=LSAT_V11C200073750\|UniProtKB=A0A9R1W5I9	Lactuca sativa	LDO
CAPAN\|EnsemblGenome=T459_29998\|UniProtKB=A0A2G2Y738	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400019694\|UniProtKB=M1BQQ3	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc04g051410.3\|UniProtKB=A0A3Q7G4V4	Solanum lycopersicum	LDO
BRANA\|Gene_ORFName=DARMORV10_C03P77810.1\|UniProtKB=A0A078FCP4	Brassica napus	LDO
MANES\|EnsemblGenome=MANES_12G145600\|UniProtKB=A0A2C9UXS3	Manihot esculenta	LDO
JUGRE\|EnsemblGenome=Jr01_15400\|UniProtKB=A0A2I4DHZ4	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr01_15370\|UniProtKB=A0A2I4DI02	Juglans regia	LDO
SELML\|EnsemblGenome=SELMODRAFT_2719\|UniProtKB=D8S7D6	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_2558\|UniProtKB=D8SZ62	Selaginella moellendorffii	LDO
MARPO\|EnsemblGenome=MARPO_0003s0311\|UniProtKB=A0A2R6XTQ1	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000420090\|UniProtKB=A0A1Y1HTR9	Klebsormidium nitens	LDO