PANTHER Gene Information

Gene Symbol(s):

aman-2

Organism:

Caenorhabditis elegans

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Gene Name:

Alpha-mannosidase

Gene ID:

WBGene00010284

Protein ID:

Q2PJ74

Persistent Id:

PTN000176467

Alternate Ids:

Q2PJ74(Synonym)	F58H1(WormBase_TRS)
CAJ55257(EMBL-CDS)	BX284605(EMBL)
83764267(GI)	WBGene00010284(Ensembl)
Q2PJ74_CAEEL(UniProtKB-ID)	NM_073594(refSeq)
WBGene00010284(WormBase)	179632(GeneID)
CE39509(WormBase_PRO)
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PANTHER Classification

PANTHER Family:	ALPHA-MANNOSIDASE (PTHR11607)
PANTHER Subfamily:	LYSOSOMAL ALPHA-MANNOSIDASE (PTHR11607:SF3)
PANTHER GO-slim Molecular Function:	hydrolase activity, hydrolyzing O-glycosyl compounds
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	glycosidase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	alpha-mannosidase activity, catalytic activity, metal ion binding, carbohydrate binding, hydrolase activity, acting on glycosyl bonds
GO BP Complete:	carbohydrate metabolic process, N-glycan processing, mannose metabolic process
GO CC Complete:	membrane, Golgi membrane, Golgi apparatus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

N-glycan antennae elongation in the medial/trans-Golgi, Transport to the Golgi and subsequent modification, Asparagine N-linked glycosylation, Reactions specific to the complex N-glycan synthesis pathway, Post-translational protein modification, Metabolism of proteins

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6824\|UniProtKB=Q16706	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017122.4\|UniProtKB=H2R5G6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001547.4\|UniProtKB=G3QGR6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000003316.4\|UniProtKB=F7EHM7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=104669\|UniProtKB=P27046	Mus musculus	LDO
RAT\|RGD=3038\|UniProtKB=P28494	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000025029.5\|UniProtKB=F1N7T2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000014195.5\|UniProtKB=A0A5G2RDR7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022893.4\|UniProtKB=F6VHV0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000009423.6\|UniProtKB=M3WBE5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004163.1\|UniProtKB=A0A8I3RTC2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001310.4\|UniProtKB=F7BEM8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011397.4\|UniProtKB=F6SBF5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010009762.1\|UniProtKB=A0A8V0Y7C8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006965.4\|UniProtKB=H9GC89	Anolis carolinensis	LDO
XENLA\|Gene=man2a1.S\|UniProtKB=A0A8J1M3V4	Xenopus laevis	LDO
XENLA\|Gene=man2a1.L\|UniProtKB=A0A1L8I1K0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-961025\|UniProtKB=A9UM36	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000022307.1\|UniProtKB=A0A3B3HG10	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060526-31\|UniProtKB=A0A0R4IVS5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010432.1\|UniProtKB=W5MWN5	lepisosteus oculatus	LDO
HUMAN\|HGNC=6825\|UniProtKB=P49641	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000007463.6\|UniProtKB=H2QA36	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000008186.3\|UniProtKB=G3QYR7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000005103.4\|UniProtKB=A0A1D5RIL8	Macaca mulatta	O
MOUSE\|MGI=MGI=2150656\|UniProtKB=Q8BRK9	Mus musculus	O
RAT\|RGD=1310238\|UniProtKB=A0A0G2JWG1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000018905.5\|UniProtKB=A0A3Q1M671	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000001819.5\|UniProtKB=A0A287ACZ4	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000018866.3\|UniProtKB=A0A9L0T8V4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000006094.6\|UniProtKB=M3W597	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845001985.1\|UniProtKB=A0A8I3RQC8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000019461.5\|UniProtKB=F6RWB3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000008973.3\|UniProtKB=F7G2I4	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010000048.1\|UniProtKB=A0A8V0X4B9	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004290.3\|UniProtKB=H9G8Z8	Anolis carolinensis	O
XENLA\|Gene=man2a2.S\|UniProtKB=A0A8J1MRV3	Xenopus laevis	O
XENLA\|Gene=man2a2.L\|UniProtKB=A0A8J0UNI0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-981388\|UniProtKB=Q6DIG4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000011897.2\|UniProtKB=H2M8T5	Oryzias latipes	O
DANRE\|Gene=man2a2\|UniProtKB=A0A8M3AWC8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015097.1\|UniProtKB=W5ND75	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000012920.2\|UniProtKB=F6RMI2	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118411916\|UniProtKB=A0A9J7MKH6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC594620\|UniProtKB=A0A7M7MYC3	Strongylocentrotus purpuratus	LDO
CAEBR\|Gene_ORFName=CBG23330\|UniProtKB=A8Y462	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00280086\|UniProtKB=A0A2A6CN95	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00272685\|UniProtKB=A0A2A6BRC8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0026616\|UniProtKB=Q9VF33	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004032\|UniProtKB=Q7QH78	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC014283\|UniProtKB=D6WL14	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_380\|UniProtKB=E9G740	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW011337\|UniProtKB=B7Q4P5	Ixodes scapularis	O
DROME\|FlyBase=FBgn0011740\|UniProtKB=Q24451	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004020\|UniProtKB=Q7PMM6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009186\|UniProtKB=D6WTA9	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW018027\|UniProtKB=B7PF17	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG110840\|UniProtKB=T1EF56	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g166900\|UniProtKB=A7S628	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG60265\|UniProtKB=B3S7R6	Trichoplax adhaerens	LDO
AMBTC\|EnsemblGenome=AMTR_s00055p00209810\|UniProtKB=U5D7B5	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_334G00070\|UniProtKB=A0A0K9PAG7	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma07_g02180\|UniProtKB=A0A804JR89	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_005719mg\|UniProtKB=K3XUW2	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3010G100800\|UniProtKB=C5Z7K3	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb280070\|UniProtKB=A0A804PW75	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb371770\|UniProtKB=A0A804UI86	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os06g0245700\|UniProtKB=A0A0P0WUK6	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g44550v3\|UniProtKB=I1GZC6	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0668450\|UniProtKB=A0A8I6YLL1	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS7D02G199200\|UniProtKB=A0A3B6TNX2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7B02G103100\|UniProtKB=A0A3B6SBJ5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G236900\|UniProtKB=A0A3B6RHJ2	Triticum aestivum	LDO
NELNU\|Gene=LOC104607979\|UniProtKB=A0A1U8AVC2	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110786831\|UniProtKB=A0A9R0IFD8	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0652981\|UniProtKB=A0A251SKC7	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200083260\|UniProtKB=A0A9R1XVD2	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a000435mg\|UniProtKB=A0A022RY86	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_06903\|UniProtKB=A0A1U8FQH0	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400001394\|UniProtKB=M0ZLV4	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc02g087290.3\|UniProtKB=A0A3Q7F8G5	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107829947\|UniProtKB=A0A1S4DHR3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107777832\|UniProtKB=A0A1S3YMI8	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi14g01872\|UniProtKB=F6HV68	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J02166\|UniProtKB=A0A059AGP2	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra006275\|UniProtKB=M4CPY6	Brassica campestris	O
BRACM\|EnsemblGenome=Bra023496\|UniProtKB=A0A3P5ZYS4	Brassica campestris	LDO
ARATH\|TAIR=locus=2147855\|UniProtKB=Q9LFR0	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107888651\|UniProtKB=A0A1U8HQK3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107958597\|UniProtKB=A0A1U8PFA7	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107892313\|UniProtKB=A0A1U8I3N8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107955563\|UniProtKB=A0A1U8P6I9	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_017957\|UniProtKB=A0A061EEA0	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g001061mg\|UniProtKB=A0A067FG37	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G350400v3\|UniProtKB=A0A2K2C8L9	Populus trichocarpa	LDO
POPTR\|EnsemblGenome=POPTR_017G073900v3\|UniProtKB=B9IJP2	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_15G179800\|UniProtKB=A0A2C9UGS8	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0852760\|UniProtKB=B9RUH3	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_13G068100\|UniProtKB=K7LXD3	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_19G015900\|UniProtKB=I1N5Z3	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g071680\|UniProtKB=G7JJU9	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_6g008850\|UniProtKB=G7KJH1	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr01_03730\|UniProtKB=A0A2I4EUJ4	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G829090\|UniProtKB=A0A0A0LFD6	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G276800\|UniProtKB=M5XBJ9	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_228\|UniProtKB=D8TD14	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_154366\|UniProtKB=D8SD28	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_116442\|UniProtKB=D8SH82	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c23_10010\|UniProtKB=A0A2K1IIR4	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0060s0008\|UniProtKB=A0A2R6WST1	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000020350\|UniProtKB=A0A1Y1HIH9	Klebsormidium nitens	LDO