PANTHER Gene Information   
Gene Symbol(s): Otulin
Organism: Mus musculus
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Gene Name: Ubiquitin thioesterase otulin
Gene ID: MGI:3577015
Protein ID: Q3UCV8
Persistent Id: PTN002133477
Alternate Ids:
Deubiquitinating enzyme otulin {ECO:0000250|UniProtKB:Q96BN8}(Synonym) ENSMUSP00000057893(Ensembl_PRO)
56789031(GI) ENSMUST00000059662(Ensembl_TRS)
NP_001013814(refSeq) 3.4.19.12 {ECO:0000269|PubMed:23708998, ECO:0000269|PubMed:29950720}(EC)
AAH87945(EMBL-CDS) Otulin{ECO:0000312|MGI:MGI:3577015}(Symbol)
ENSMUSG00000046034(Ensembl) AK134955(EMBL)
MGI:3577015(MGI) OTUL_MOUSE(UniProtKB-ID)
432940(GeneID) Q8R027(AltAccession)
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PANTHER Classification
PANTHER Family: OTU DEUBIQUITINASE WITH LINEAR LINKAGE-SPECIFICITY A-RELATED (PTHR33662)
PANTHER Subfamily: UBIQUITIN THIOESTERASE OTULIN (PTHR33662:SF2)  
PANTHER GO-slim Molecular Function: cysteine-type deubiquitinase activity
PANTHER GO-slim Biological Process: innate immune response
negative regulation of NF-kappaB transcription factor activity
protein deubiquitination
regulation of signal transduction
negative regulation of inflammatory response
PANTHER GO-slim Cellular Component: cytoplasm
PANTHER protein class:
Pathway Categories: No pathway information available
GO MF Complete: cysteine-type deubiquitinase activity, cysteine-type peptidase activity, peptidase activity, hydrolase activity
GO BP Complete: angiogenesis, negative regulation of NF-kappaB transcription factor activity, nucleotide-binding oligomerization domain containing 2 signaling pathway, innate immune response, negative regulation of inflammatory response, regulation of canonical Wnt signaling pathway, proteolysis, regulation of tumor necrosis factor-mediated signaling pathway, sprouting angiogenesis, protein linear deubiquitination, Wnt signaling pathway, immune system process
GO CC Complete: cytoplasm, LUBAC complex
Reactome Pathways: Protein ubiquitination, Metabolism of proteins, Synthesis of active ubiquitin: roles of E1 and E2 enzymes, Post-translational protein modification