PANTHER Gene Information

Gene Symbol(s):

Agxt2

Organism:

Mus musculus

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Gene Name:

Alanine--glyoxylate aminotransferase 2, mitochondrial

Gene ID:

MGI:2146052

Protein ID:

Q3UEG6

Persistent Id:

PTN000241053

Alternate Ids:

AGT2_MOUSE(UniProtKB-ID)	MGI:2146052(MGI)
NP_001297665(refSeq)	B9EIZ8(AltAccession)
893712573(GI)	2.6.1.40(EC)
268782(GeneID)	ENSMUSG00000089678(Ensembl)
Beta-alanine-pyruvate aminotransferase(Synonym)	ENSMUSP00000106171(Ensembl_PRO)
BAE28945(EMBL-CDS)	AK149538(EMBL)
ENSMUST00000110542(Ensembl_TRS)	Agxt2(Symbol)
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PANTHER Classification

PANTHER Family:	FAMILY NOT NAMED (PTHR45688)
PANTHER Subfamily:	ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL (PTHR45688:SF3)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	pyridoxal phosphate binding, (R)-3-amino-2-methylpropionate-pyruvate transaminase activity, alanine-glyoxylate transaminase activity, beta-alanine:pyruvate transaminase activity
GO BP Complete:	L-alanine catabolic process, by transamination, positive regulation of nitric oxide biosynthetic process, glycine biosynthetic process, by transamination of glyoxylate, N(omega),N(omega)-dimethyl-L-arginine catabolic process, glyoxylate catabolic process
GO CC Complete:	mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism, Glyoxylate metabolism and glycine degradation, Metabolism of amino acids and derivatives

Orthologs

ID	Organism	Type
HUMAN\|HGNC=14412\|UniProtKB=Q9BYV1	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000016786.5\|UniProtKB=H2QQR4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006579.3\|UniProtKB=G3QUN3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006301.4\|UniProtKB=A0A1D5QGI6	Macaca mulatta	LDO
RAT\|RGD=621767\|UniProtKB=Q64565	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000007690.4\|UniProtKB=F1MLG7	Bos taurus	LDO
BOVIN\|Gene=AGXT2\|UniProtKB=Q17QF0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000016829.5\|UniProtKB=A0A286ZST3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000021933.4\|UniProtKB=A0A5F5Q1S1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000008826.6\|UniProtKB=A0A5F5XHD4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845000838.1\|UniProtKB=A0A8I3MGB1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000020379.4\|UniProtKB=F7F6D0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014528.3\|UniProtKB=A0A6I8P298	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010013296.1\|UniProtKB=A0A8V0YJP6	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008668.4\|UniProtKB=H9GE87	Anolis carolinensis	LDO
XENLA\|Gene=agxt2.L\|UniProtKB=A0A1L8I3B4	Xenopus laevis	O
XENLA\|Gene=agxt2.S\|UniProtKB=A0A1L8HRS1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-993827\|UniProtKB=A0A6I8SPU7	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000027864.1\|UniProtKB=A0A3B3IJD0	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050913-100\|UniProtKB=Q4V8R2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011796.1\|UniProtKB=W5N1L2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002644.3\|UniProtKB=F7AJ78	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118417587\|UniProtKB=A0A9J7LBG2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC594821\|UniProtKB=A0A7M7N5N0	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00020382\|UniProtKB=O02158	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00033756\|UniProtKB=A8XFU0	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00091264\|UniProtKB=A0A8R1Y5M3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0037186\|UniProtKB=A8E6R2	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP012404\|UniProtKB=A0A453YY69	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC011528\|UniProtKB=D6W6C3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_128102\|UniProtKB=E9GEQ7	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG185816\|UniProtKB=T1FNB9	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g214753\|UniProtKB=A7SMZ4	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG63204\|UniProtKB=B3RJD8	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_26129\|UniProtKB=A9V1F9	Monosiga brevicollis	LDO
CHLRE\|EnsemblGenome=CHLRE_03g182800v5\|UniProtKB=A0A2K3DXV2	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00010p00232210\|UniProtKB=W1NFQ7	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_85G00040\|UniProtKB=A0A0K9NMX8	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma10_g18940\|UniProtKB=A0A804KXU6	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_035263mg\|UniProtKB=K4A8Q7	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G488200\|UniProtKB=A0A1B6QQ80	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb005550\|UniProtKB=A0A1D6JQ63	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0171900\|UniProtKB=Q10R45	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g73120v3\|UniProtKB=I1H969	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0403790\|UniProtKB=F2D6C1	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS4A02G015900\|UniProtKB=A0A3B6HMZ7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G288100\|UniProtKB=A0A3B6ITH3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G286900\|UniProtKB=A0A3B6JMH8	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_023317\|UniProtKB=A0A1U8ANJ7	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110794781\|UniProtKB=A0A9R0K1U8	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0702751\|UniProtKB=A0A251S6F2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0648471\|UniProtKB=A0A251SI24	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200073660\|UniProtKB=A0A9R1XN16	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a005616mg\|UniProtKB=A0A022Q8W3	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_30335\|UniProtKB=B5LAW1	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400012800\|UniProtKB=M1AYY7	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc04g054310.3\|UniProtKB=A0A3Q7G5T0	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107815286\|UniProtKB=A0A1S4C601	Nicotiana tabacum	O
TOBAC\|Gene=LOC107827733\|UniProtKB=A0A1S4DAJ5	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi07g01808\|UniProtKB=D7SW34	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_H04825\|UniProtKB=A0A059B923	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C01P00680.1\|UniProtKB=A0A078I0N9	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A01P00550.1\|UniProtKB=A0A078HTY5	Brassica napus	O
BRACM\|EnsemblGenome=Bra011843\|UniProtKB=M4D5T6	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00039306001\|UniProtKB=A0A078JEX0	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra010671\|UniProtKB=M4D2H1	Brassica campestris	LDO
ARATH\|TAIR=locus=2135237\|UniProtKB=Q940M2	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107914378\|UniProtKB=A0A1U8KDN0	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_001213\|UniProtKB=A0A061DJU2	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g011777mg\|UniProtKB=A0A067DM36	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_007G085600v3\|UniProtKB=B9HFU8	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_13G089400\|UniProtKB=A0A2C9UQE1	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0193980\|UniProtKB=B9T1D1	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_18G021000\|UniProtKB=K7MPG5	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G140200\|UniProtKB=I1KT81	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_11G236200\|UniProtKB=A0A0R0HYB1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_05G182600\|UniProtKB=A0A0R4J3C5	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_8g091660\|UniProtKB=B7FLF5	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr01_16190\|UniProtKB=A0A2I4DR33	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G036590\|UniProtKB=A0A0A0KWI3	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G177100\|UniProtKB=M5VXX8	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_1G573800\|UniProtKB=M5XCH2	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_235068\|UniProtKB=D8STE5	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_143081\|UniProtKB=D8R0S3	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c10_22930\|UniProtKB=A9RWB7	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0025s0002\|UniProtKB=A0A2R6XAZ8	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001510300\|UniProtKB=A0A1Y1I5Z0	Klebsormidium nitens	LDO