PANTHER Gene Information

Gene Symbol(s):

P2rx5

Organism:

Mus musculus

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Gene Name:

P2X purinoceptor

Gene ID:

MGI:2137026

Protein ID:

Q3UYI1

Persistent Id:

PTN000013070

Alternate Ids:

MGI:2137026(MGI)	74145156(GI)
ENSMUSP00000006104(Ensembl_PRO)	94045(GeneID)
Q3UYI1(Synonym)	ENSMUST00000006104(Ensembl_TRS)
BAE22231(EMBL-CDS)	AK134662(EMBL)
Q3UYI1_MOUSE(UniProtKB-ID)	ENSMUSG00000005950(Ensembl)
NP_201578(refSeq)
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PANTHER Classification

PANTHER Family:	P2X PURINOCEPTOR (PTHR10125)
PANTHER Subfamily:	P2X PURINOCEPTOR 5 (PTHR10125:SF12)
PANTHER GO-slim Molecular Function:	ligand-gated monoatomic cation channel activity excitatory extracellular ligand-gated monoatomic ion channel activity
PANTHER GO-slim Biological Process:	calcium ion transmembrane transport
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	ligand-gated ion channel

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	extracellularly ATP-gated monoatomic cation channel activity, ATP binding, identical protein binding, ATP-gated ion channel activity, ligand-gated monoatomic anion channel activity, voltage-gated monoatomic ion channel activity
GO BP Complete:	regulation of skeletal muscle tissue regeneration, response to zinc ion, response to ATP, positive regulation of calcium ion import across plasma membrane, response to calcium ion, monoatomic cation transmembrane transport, cell surface receptor signaling pathway, response to pH, chloride transport
GO CC Complete:	cytosol, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Platelet homeostasis, Hemostasis, Elevation of cytosolic Ca2+ levels, Platelet calcium homeostasis

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8536\|UniProtKB=Q93086	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008575.6\|UniProtKB=H2R9U8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000009909.3\|UniProtKB=G3R366	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000023392.4\|UniProtKB=F7E3H6	Macaca mulatta	LDO
RAT\|RGD=620256\|UniProtKB=P51578	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015258.6\|UniProtKB=F1MUF3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017868.5\|UniProtKB=A0A287AVK8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024637.3\|UniProtKB=A0A9L0RBT3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000007925.6\|UniProtKB=A0A5F5XQ52	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845016566.1\|UniProtKB=A0A8I3NX68	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006728.3\|UniProtKB=F7CX61	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012692.3\|UniProtKB=F7A812	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029739.1\|UniProtKB=A0A8V1AQ04	Gallus gallus	LDO
XENLA\|Gene=p2rx5.L\|UniProtKB=A0A1L8HD30	Xenopus laevis	O
XENLA\|Gene=p2rx5.S\|UniProtKB=A0A1L8H4Y2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1006287\|UniProtKB=A0A6I8SK99	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000012047.2\|UniProtKB=H2M999	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030319-7\|UniProtKB=Q7SZM1	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030319-5\|UniProtKB=B0R182	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003384.1\|UniProtKB=W5M6K1	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118426535\|UniProtKB=A0A9J7N538	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC591536\|UniProtKB=A0A7M7STW0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115926462\|UniProtKB=A0A7M7T1I6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC587360\|UniProtKB=A0A7M7PAM8	Strongylocentrotus purpuratus	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_310786\|UniProtKB=E9FVI6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_206200\|UniProtKB=E9FVI5	Daphnia pulex	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g104653\|UniProtKB=A7S4Q4	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG57279\|UniProtKB=B3RZ03	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG59819\|UniProtKB=B3S6I7	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_31366\|UniProtKB=A9URI5	Monosiga brevicollis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_33275\|UniProtKB=F4P4K8	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0288061\|UniProtKB=Q54JH4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_152641\|UniProtKB=F0ZLX2	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0272004\|UniProtKB=Q86JM7	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0288335\|UniProtKB=Q54J33	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0275293\|UniProtKB=Q553Y1	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0275191\|UniProtKB=Q553Y0	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_90884\|UniProtKB=F1A5G0	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_74417\|UniProtKB=F0Z7P1	Dictyostelium purpureum	O