PANTHER Gene Information   
Gene Symbol(s): Nkx3-1
Organism: Rattus norvegicus
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Gene Name: NK3 homeobox 1
Gene ID: 1305369
Protein ID: Q497B7
Persistent Id: PTN000678371
Alternate Ids:
Q497B7_RAT(UniProtKB-ID) NP_001029316(refSeq)
ENSRNOG00000015477(Ensembl) 77628002(GI)
ENSRNOT00000020753(Ensembl_TRS) Q497B7(Synonym)
ENSRNOP00000020753(Ensembl_PRO) 1305369(RGD)
305999(GeneID)
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PANTHER Classification
PANTHER Family: HOMEOBOX PROTEIN NKX (PTHR24340)
PANTHER Subfamily: HOMEOBOX PROTEIN NKX-3.1 (PTHR24340:SF38)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: cell differentiation
regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: homeodomain transcription factor
Pathway Categories: No pathway information available
GO MF Complete: histone deacetylase binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription cis-regulatory region binding, sequence-specific DNA binding, MADS box domain binding, cysteine-type endopeptidase activator activity involved in apoptotic process, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA binding, DNA-binding transcription factor activity, nuclear receptor activity, transcription regulator inhibitor activity, nuclear estrogen receptor binding, sequence-specific double-stranded DNA binding, DNA-binding transcription factor binding
GO BP Complete: branching involved in prostate gland morphogenesis, male gonad development, negative regulation of cell population proliferation, positive regulation of cell population proliferation, epithelial cell proliferation involved in prostate gland development, salivary gland development, branching morphogenesis of an epithelial tube, positive regulation of transcription by RNA polymerase II, positive regulation of DNA-binding transcription factor activity, epithelial cell proliferation involved in salivary gland morphogenesis, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of transcription by RNA polymerase II, heart development, epithelial cell proliferation, negative regulation of DNA-templated transcription, positive regulation of cell division, positive regulation of DNA-templated transcription, apoptotic process, positive regulation of androgen secretion, cellular response to tumor necrosis factor, response to testosterone, cellular response to hypoxia, androgen receptor signaling pathway, positive regulation of intrinsic apoptotic signaling pathway, negative regulation of epithelial cell proliferation involved in prostate gland development, regulation of protein localization, DNA damage response, pharyngeal system development, positive regulation of mitotic cell cycle, dorsal aorta development, cellular response to steroid hormone stimulus, negative regulation of gene expression, urogenital system development, metanephros development, somitogenesis, positive regulation of gene expression, positive regulation of protein phosphorylation, negative regulation of epithelial cell proliferation, cellular response to interleukin-1, cellular response to xenobiotic stimulus, positive regulation of cysteine-type endopeptidase activity, prostate gland development, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, positive regulation of apoptotic signaling pathway
GO CC Complete: nucleus, site of DNA damage, cytosol, nucleoplasm
Reactome Pathways: -