PANTHER Gene Information

Gene Symbol(s):

FGFR

Organism:

Ciona intestinalis

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Gene Name:

Fibroblast growth factor receptor

Gene ID:

FGFR

Protein ID:

Q4H3K6

Persistent Id:

PTN001974957

Alternate Ids:

BAE06421(EMBL-CDS)	113195651(GI)
FGFR(Symbol)	AB210416(EMBL)
445706(GeneID)	Ci-FGFR(Synonym)
NM_001044355(refSeq)	FGFR_CIOIN(UniProtKB-ID)
2.7.10.1(EC)
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PANTHER Classification

PANTHER Family:	TYROSINE-PROTEIN KINASE RECEPTOR (PTHR24416)
PANTHER Subfamily:	FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1-RELATED (PTHR24416:SF550)
PANTHER GO-slim Molecular Function:	transmembrane receptor protein tyrosine kinase activity
PANTHER GO-slim Biological Process:	transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of kinase activity multicellular organism development
PANTHER GO-slim Cellular Component:	receptor complex plasma membrane
PANTHER protein class:	transmembrane signal receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	placental growth factor receptor activity, stem cell factor receptor activity, brain-derived neurotrophic factor receptor activity, macrophage colony-stimulating factor receptor activity, protein tyrosine kinase collagen receptor activity, insulin-like growth factor receptor activity, boss receptor activity, GPI-linked ephrin receptor activity, epidermal growth factor receptor activity, transmembrane-ephrin receptor activity, hepatocyte growth factor receptor activity, platelet-derived growth factor beta-receptor activity, fibroblast growth factor receptor activity, platelet-derived growth factor alpha-receptor activity, ATP binding, protein tyrosine kinase activity, insulin receptor activity, histone H2AXY142 kinase activity, fibroblast growth factor binding, histone H3Y41 kinase activity
GO BP Complete:	vascular endothelial growth factor receptor-1 signaling pathway, multicellular organism development, insulin receptor signaling pathway, epidermal growth factor receptor signaling pathway, platelet-derived growth factor receptor-alpha signaling pathway, macrophage colony-stimulating factor signaling pathway, positive regulation of cell population proliferation, platelet-derived growth factor receptor-beta signaling pathway, insulin-like growth factor receptor signaling pathway, cell surface receptor protein tyrosine kinase signaling pathway, fibroblast growth factor receptor signaling pathway, collagen-activated tyrosine kinase receptor signaling pathway, hepatocyte growth factor receptor signaling pathway, chromatin remodeling, brain-derived neurotrophic factor receptor signaling pathway, ephrin receptor signaling pathway, Kit signaling pathway
GO CC Complete:	membrane, receptor complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3688\|UniProtKB=P11362	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020176.7\|UniProtKB=A0A2I3RMA9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013080.3\|UniProtKB=G3RBC6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000022478.4\|UniProtKB=F7A4U3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=95522\|UniProtKB=P16092	Mus musculus	LDO
RAT\|RGD=620713\|UniProtKB=Q04589	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015457.6\|UniProtKB=A0A3Q1LUE0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000015815.6\|UniProtKB=K7GQJ1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000015006.4\|UniProtKB=A0A5F5PNY6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013612.6\|UniProtKB=A0A2I2UK29	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845012040.1\|UniProtKB=A0A8I3NNZ2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000010647.3\|UniProtKB=F7D4I5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003252.4\|UniProtKB=A0A6I8NZC2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010017332.1\|UniProtKB=A0A8V0Z7L6	Gallus gallus	LDO
CHICK\|Gene=FGFR1\|UniProtKB=P21804	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000018003.3\|UniProtKB=H9GPZ1	Anolis carolinensis	LDO
XENLA\|Gene=xfgfra2\|UniProtKB=A0A8J1MNY1	Xenopus laevis	O
XENLA\|Gene=fgfr1\|UniProtKB=P22182	Xenopus laevis	O
XENLA\|Gene=fgfr1.S\|UniProtKB=B7ZRE2	Xenopus laevis	O
XENLA\|Gene=fgfr1.L\|UniProtKB=Q91897	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1018554\|UniProtKB=A0A8J0SFH4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000000321.2\|UniProtKB=A0A3B3IM82	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000014206.2\|UniProtKB=H2MGT2	Oryzias latipes	LDO
DANRE\|Gene=fgfr1b\|UniProtKB=A0A8M1NUM7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-255\|UniProtKB=Q90Z00	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014985.1\|UniProtKB=W5NCV1	lepisosteus oculatus	LDO
HUMAN\|HGNC=3689\|UniProtKB=P21802	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000003003.7\|UniProtKB=H2Q2P3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000008336.3\|UniProtKB=A0A2I2YZH3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000009594.4\|UniProtKB=G7N1A1	Macaca mulatta	O
MOUSE\|MGI=MGI=95523\|UniProtKB=P21803	Mus musculus	O
RAT\|RGD=2611\|UniProtKB=F1LSG7	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000014064.6\|UniProtKB=A0A3Q1LRU7	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000013960.4\|UniProtKB=F7CXP1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000003692.6\|UniProtKB=A0A5F5Y2A8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845019372.1\|UniProtKB=A0A8I3P6D2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000008525.4\|UniProtKB=F7DHF8	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000029096.2\|UniProtKB=A0A6I8NDM2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010001411.1\|UniProtKB=A0A8V0XB17	Gallus gallus	O
CHICK\|Gene=FGFR2\|UniProtKB=P18461	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000017206.4\|UniProtKB=G1KTN6	Anolis carolinensis	O
XENLA\|Gene=fgfr2.S\|UniProtKB=A0A8J0TEF2	Xenopus laevis	O
XENLA\|Gene=fgfr2.L\|UniProtKB=A0A8J0T8A2	Xenopus laevis	O
XENLA\|Gene=fgfr2\|UniProtKB=Q03364	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1018296\|UniProtKB=A0A8J0SHM8	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000013277.2\|UniProtKB=H2MDJ2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030323-1\|UniProtKB=Q8JG38	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000008752.1\|UniProtKB=W5MQK3	lepisosteus oculatus	O
HUMAN\|HGNC=3691\|UniProtKB=P22455	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000017574.6\|UniProtKB=H2QS34	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002917.3\|UniProtKB=G3RPD8	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=95525\|UniProtKB=Q03142	Mus musculus	O
RAT\|RGD=2612\|UniProtKB=Q498D6	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000010543.6\|UniProtKB=F1MN51	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000014047.6\|UniProtKB=F1S3B8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000020869.4\|UniProtKB=A0A5F5PXI3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000016224.6\|UniProtKB=M3WNB0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845010987.1\|UniProtKB=A0A8I3NHA2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000004899.4\|UniProtKB=F7C211	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007493.3\|UniProtKB=F6QKY2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010011810.1\|UniProtKB=F1NCL8	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000005410.4\|UniProtKB=G1KE82	Anolis carolinensis	O
XENLA\|Gene=fgfr4\|UniProtKB=Q91743	Xenopus laevis	O
XENLA\|Gene=fgfr4.S\|UniProtKB=Q9PSV8	Xenopus laevis	O
XENLA\|Gene=fgfr4.L\|UniProtKB=Q9PSV9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-478699\|UniProtKB=Q28GC1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000013964.2\|UniProtKB=H2MFY7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980526-488\|UniProtKB=Q90413	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012293.1\|UniProtKB=W5N3C2	lepisosteus oculatus	O
HUMAN\|HGNC=3690\|UniProtKB=P22607	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000015836.7\|UniProtKB=K7CPL4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015081.3\|UniProtKB=G3QKA0	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000019945.4\|UniProtKB=F7FZR9	Macaca mulatta	O
MOUSE\|MGI=MGI=95524\|UniProtKB=Q61851	Mus musculus	O
RAT\|RGD=620714\|UniProtKB=F1LSN4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000007164.6\|UniProtKB=A0A3Q1MPT9	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000019533.4\|UniProtKB=F6U520	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000018385.5\|UniProtKB=A0A337SDG1	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845013339.1\|UniProtKB=A0A8I3NS74	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000004268.4\|UniProtKB=A0A5F8GLT3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000003354.4\|UniProtKB=F6VBA5	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010016940.1\|UniProtKB=A0A8V0YYZ7	Gallus gallus	O
CHICK\|Gene=FGFR3\|UniProtKB=P18460	Gallus gallus	O
XENLA\|Gene=fgfr3\|UniProtKB=O42127	Xenopus laevis	O
XENLA\|Gene=fgfr3.L\|UniProtKB=A0A8J1MCZ3	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-479255\|UniProtKB=A0A8J0SG86	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000017972.2\|UniProtKB=H2MUP1	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-000816-1\|UniProtKB=Q9I8X3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007042.1\|UniProtKB=W5MJI2	lepisosteus oculatus	O
BRAFL\|Gene=LOC118414472\|UniProtKB=A0A9J7L2Z7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118413855\|UniProtKB=A0A9J7L0C8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=GeneID_373310\|UniProtKB=Q26614	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001184\|UniProtKB=Q10656	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG17516\|UniProtKB=A8XRD1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00278198\|UniProtKB=A0A2A6B247	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0010389\|UniProtKB=Q07407	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0285896\|UniProtKB=Q09147	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP003108\|UniProtKB=A0A1S4GGY3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC004713\|UniProtKB=D6W6I2	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_300042\|UniProtKB=E9FS22	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW018261\|UniProtKB=B7PFB4	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG70474\|UniProtKB=T1G069	helobdella robusta	LDO
HELRO\|EnsemblGenome=HelroG81195\|UniProtKB=T1G4A9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG102694\|UniProtKB=T1EDB0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG132900\|UniProtKB=T1EHZ9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG79669\|UniProtKB=T1G3S0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG131255\|UniProtKB=T1EHV6	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g81258\|UniProtKB=A7RHA0	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g98570\|UniProtKB=A7RZ71	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g98616\|UniProtKB=A7RZ69	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g31143\|UniProtKB=A7RHA4	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_37376\|UniProtKB=A9V1C1	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_20579\|UniProtKB=Q8WRF4	Monosiga brevicollis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_12702\|UniProtKB=A9VD25	Monosiga brevicollis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_39078\|UniProtKB=A9VC23	Monosiga brevicollis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_32678\|UniProtKB=A9V127	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_44364\|UniProtKB=A9V8G0	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_33202\|UniProtKB=A9V450	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_14040\|UniProtKB=A9UNI7	Monosiga brevicollis	O