PANTHER Gene Information

Gene Symbol(s):

Arfgap3

Organism:

Rattus norvegicus

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Gene Name:

ADP-ribosylation factor GTPase-activating protein 3

Gene ID:

1560066

Protein ID:

Q4KLN7

Persistent Id:

PTN001505443

Alternate Ids:

1046896874(GI)	XM_017595063(refSeq)
AAH99081(EMBL-CDS)	ENSRNOG00000046472(Ensembl)
ARFG3_RAT(UniProtKB-ID)	BC099081(EMBL)
ARFG3(Synonym)	Arfgap3{ECO:0000250\|UniProtKB:Q9NP61}(Symbol)
1560066(RGD)	ENSRNOT00000074960(Ensembl_TRS)
503165(GeneID)	ENSRNOP00000065256(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED (PTHR45686)
PANTHER Subfamily:	ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 3 (PTHR45686:SF1)
PANTHER GO-slim Molecular Function:	GTPase activator activity
PANTHER GO-slim Biological Process:	vesicle budding from membrane vesicle targeting, to, from or within Golgi
PANTHER GO-slim Cellular Component:
PANTHER protein class:	GTPase-activating protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metal ion binding, GTPase activator activity
GO BP Complete:	vesicle-mediated transport, presynaptic endocytosis, COPI coating of Golgi vesicle, protein secretion
GO CC Complete:	photoreceptor ribbon synapse, presynaptic active zone, cytoplasm, cytosol, Golgi membrane, Golgi apparatus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signaling by Rho GTPases, Signal Transduction, Intra-Golgi and retrograde Golgi-to-ER traffic, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Metabolism of proteins, Transport to the Golgi and subsequent modification, Post-translational protein modification, COPI-dependent Golgi-to-ER retrograde traffic, RHO GTPase cycle, RHOG GTPase cycle, Asparagine N-linked glycosylation, ER to Golgi Anterograde Transport, Golgi-to-ER retrograde transport, Vesicle-mediated transport, Membrane Trafficking, COPI-mediated anterograde transport

Orthologs

ID	Organism	Type
HUMAN\|HGNC=661\|UniProtKB=Q9NP61	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000051085.1\|UniProtKB=G2HJF0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014512.3\|UniProtKB=G3RF12	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000002229.4\|UniProtKB=A0A1D5QH88	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1913501\|UniProtKB=Q9D8S3	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000001057\|UniProtKB=Q17R07	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000037.5\|UniProtKB=F1SJR4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000023901.4\|UniProtKB=A0A9L0THJ4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000008578.5\|UniProtKB=A0A5F5Y4T9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014445.1\|UniProtKB=A0A8I3NUI5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006872.4\|UniProtKB=F6PWY1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005849.4\|UniProtKB=F6XWB4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012147.1\|UniProtKB=A0A8V0YLF1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016041.3\|UniProtKB=A0A803T991	Anolis carolinensis	LDO
XENLA\|Gene=arfgap3.L\|UniProtKB=Q1JV76	Xenopus laevis	O
XENLA\|Gene=arfgap3.S\|UniProtKB=Q7ZYR5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-493413\|UniProtKB=Q28CK6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000027675.1\|UniProtKB=H2MLA2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1\|UniProtKB=Q6TNW0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015134.1\|UniProtKB=W5NDB7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005196.3\|UniProtKB=F7B710	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000015738.2\|UniProtKB=F6R2P7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118407142\|UniProtKB=A0A9J7KHK5	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC752571\|UniProtKB=A0A7M7NZC8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC591603\|UniProtKB=A0A7M7PGI9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00017217\|UniProtKB=Q09531	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00025456\|UniProtKB=A8WUF1	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0037182\|UniProtKB=A8JNX0	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005609\|UniProtKB=Q7Q6Y0	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC007817\|UniProtKB=D2A2A4	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_300346\|UniProtKB=E9G5B9	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW018290\|UniProtKB=B7PHG6	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG188195\|UniProtKB=T1FPR6	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG64381\|UniProtKB=B3SC19	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_37355\|UniProtKB=A9V167	Monosiga brevicollis	LDO
YEAST\|SGD=S000002385\|UniProtKB=P35197	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABL164C\|UniProtKB=Q75E34	Eremothecium gossypii	O
CANAL\|CGD=CAL0000194066\|UniProtKB=A0A1D8PCP6	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_C02959g\|UniProtKB=Q6CD82	Yarrowia lipolytica	O
SCHPO\|PomBase=SPCC622.14\|UniProtKB=O94601	Schizosaccharomyces pombe	O
CRYNJ\|EnsemblGenome=CNL05690\|UniProtKB=Q5K8H3	Cryptococcus neoformans	O
PUCGT\|EnsemblGenome=PGTG_11998\|UniProtKB=E3KP17	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_93026\|UniProtKB=F4PF82	Batrachochytrium dendrobatidis	O
YEAST\|SGD=S000000924\|UniProtKB=P38682	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGL279C\|UniProtKB=Q751I5	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000179018\|UniProtKB=Q5A7M1	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D00693g\|UniProtKB=Q6CAR0	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_06033\|UniProtKB=C8V312	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G09830\|UniProtKB=Q4X1I7	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08811\|UniProtKB=Q7S8S4	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_14476\|UniProtKB=A7FA45	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_12691\|UniProtKB=Q0U6C3	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC22E12.17c\|UniProtKB=Q10367	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04391\|UniProtKB=B6K6Q3	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNH03190\|UniProtKB=Q5KD38	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_11439\|UniProtKB=A0A0D1CGQ2	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_15503\|UniProtKB=E3KYD3	Puccinia graminis	LDO
ENTH1\|EnsemblGenome=CL6EHI_004810\|UniProtKB=C4M077	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0281627\|UniProtKB=Q54TP9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_153151\|UniProtKB=F0ZN64	Dictyostelium purpureum	LDO
DICDI\|dictyBase=DDB_G0292148\|UniProtKB=Q54DK9	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_98039\|UniProtKB=F0ZM41	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_13_0710\|UniProtKB=Q4QG83	Leishmania major	O
TRYB2\|Gene_ORFName=Tb09.244.2540\|UniProtKB=Q38CW4	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_32_1230\|UniProtKB=Q4Q5F9	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.6060\|UniProtKB=Q381Z1	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_005650\|UniProtKB=A2FHQ0	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_256450\|UniProtKB=A2FHA7	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_0804900\|UniProtKB=Q8IAP4	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1244600\|UniProtKB=Q8I4Y5	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00035494001\|UniProtKB=A0C6E8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00031702001\|UniProtKB=A0BSF3	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00034533001\|UniProtKB=A0C2N8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014963001\|UniProtKB=A0DAI9	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00024511001\|UniProtKB=A0E913	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_25050\|UniProtKB=B8CDC5	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_20719\|UniProtKB=B8BQB2	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GNL6_PHYRM\|UniProtKB=H3GNL6	Phytophthora ramorum	O
PHYRM\|Gene=H3GE78_PHYRM\|UniProtKB=H3GE78	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_09g386550v5\|UniProtKB=A8J1B8	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_17g715350v5\|UniProtKB=A0A2K3CPX5	Chlamydomonas reinhardtii	LDO
ZOSMR\|Gene_ORFName=ZOSMA_26G01000\|UniProtKB=A0A0K9PEF8	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma04_g28320\|UniProtKB=A0A804IUW0	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma04_g35370\|UniProtKB=A0A804IXG6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma11_g16390\|UniProtKB=A0A804L8I2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma02_g19850\|UniProtKB=A0A804I4P2	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_035275mg\|UniProtKB=K4A8R9	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G287800\|UniProtKB=C5WRB2	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb390370\|UniProtKB=A0A804R6K9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb024360\|UniProtKB=A0A804LNN3	Zea mays	O
ORYSJ\|EnsemblGenome=Os10g0574800\|UniProtKB=Q7XBX2	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g34180v3\|UniProtKB=I1I6F1	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0053120\|UniProtKB=A0A8I6WTQ8	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS1A02G193000\|UniProtKB=A0A3B5Y0H3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G196700\|UniProtKB=A0A3B5ZTT6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G207900\|UniProtKB=A0A3B5YWS8	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_035925mg\|UniProtKB=K4AAL8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G007600\|UniProtKB=C5WS02	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb210570\|UniProtKB=B4FK00	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb064850\|UniProtKB=B4F9F9	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0854100\|UniProtKB=Q84T71	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g01090v3\|UniProtKB=I1GKN7	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0535930\|UniProtKB=F2E7R5	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G554600\|UniProtKB=A0A3B6LYR8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G554100\|UniProtKB=A0A3B6N3G6	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS4A02G323700\|UniProtKB=A0A3B6I072	Triticum aestivum	LDO
NELNU\|Gene=LOC104610346\|UniProtKB=A0A1U8B346	Nelumbo nucifera	O
NELNU\|Gene=LOC104608777\|UniProtKB=A0A1U8B9W0	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110792030\|UniProtKB=A0A9R0JZ65	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0602831\|UniProtKB=A0A251SUM0	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr03g0127311\|UniProtKB=A0A251VC44	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600328520\|UniProtKB=A0A9R1V4L9	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a007232mg\|UniProtKB=A0A022R5N5	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_07741\|UniProtKB=A0A2G2ZUI5	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_34400\|UniProtKB=A0A2G2XW94	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_04019\|UniProtKB=A0A2G3API4	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_34409\|UniProtKB=A0A2G2XWR4	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400001155\|UniProtKB=M0ZKY0	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc08g005070.3\|UniProtKB=A0A3Q7HGM9	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107771184\|UniProtKB=A0A1S3Y1M6	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107785612\|UniProtKB=A0A1S3ZDB0	Nicotiana tabacum	LDO
CAPAN\|EnsemblGenome=T459_00864\|UniProtKB=A0A2G3AFG8	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400017515\|UniProtKB=M1BH67	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc08g076920.3\|UniProtKB=A0A3Q7HRB7	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107790632\|UniProtKB=A0A1S3ZUM8	Nicotiana tabacum	O
TOBAC\|Gene=LOC107787704\|UniProtKB=A0A1S3ZKF9	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi02g00699\|UniProtKB=D7TTW7	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_D02202\|UniProtKB=A0A059CHP7	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00080265001\|UniProtKB=A0A078I3U0	Brassica napus	O
BRACM\|EnsemblGenome=Bra012634\|UniProtKB=M4D824	Brassica campestris	O
BRACM\|EnsemblGenome=Bra013265\|UniProtKB=M4D9V5	Brassica campestris	O
ARATH\|TAIR=locus=2141060\|UniProtKB=Q8H100	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=DARMORV10_A04P26760.1\|UniProtKB=A0A078J4Q7	Brassica napus	O
BRACM\|EnsemblGenome=Bra017330\|UniProtKB=M4DLE9	Brassica campestris	O
ARATH\|TAIR=locus=2063429\|UniProtKB=O82171	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=DARMORV10_A06P45700.1\|UniProtKB=A0A078J6B6	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra024999\|UniProtKB=M4E893	Brassica campestris	LDO
ARATH\|TAIR=locus=2178545\|UniProtKB=Q9FIQ0	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107946832\|UniProtKB=A0A1U8NFP3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107890612\|UniProtKB=A0A1U8I325	Gossypium hirsutum	O
GOSHI\|Gene=LOC107946751\|UniProtKB=A0A1U8NCF2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107935173\|UniProtKB=A0A1U8MCD5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107950174\|UniProtKB=A0A1U8NN88	Gossypium hirsutum	O
GOSHI\|Gene=LOC107912182\|UniProtKB=A0A1U8JZN7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107924282\|UniProtKB=A0A1U8L9S8	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107939765\|UniProtKB=A0A1U8MSV0	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_015712\|UniProtKB=A0A061G472	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g015634mg\|UniProtKB=A0A067DQ39	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_003G092300v3\|UniProtKB=B9N2M5	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G142100v3\|UniProtKB=B9MU26	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_17G010700\|UniProtKB=A0A2C9U4X1	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1279410\|UniProtKB=B9SNV8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_01G096300\|UniProtKB=I1J6C3	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G271700\|UniProtKB=I1KX25	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_8g067090\|UniProtKB=G7LHQ6	Medicago truncatula	LDO
MEDTR\|EnsemblGenome=MTR_8g067080\|UniProtKB=G7LHQ5	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr09_07540\|UniProtKB=A0A2I4DWF7	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr02_13010\|UniProtKB=A0A2I4EDU3	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_3G902260\|UniProtKB=A0A0A0LF23	Cucumis sativus	O
CUCSA\|EnsemblGenome=Csa_3G011600\|UniProtKB=A0A0A0L570	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G035300\|UniProtKB=M5WEI6	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_124944\|UniProtKB=D8SU52	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_44869\|UniProtKB=D8T386	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c1_20430\|UniProtKB=A0A2K1L8V2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c2_23830\|UniProtKB=A0A7I4D671	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0063s0097\|UniProtKB=A0A2R6WRT8	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000850220\|UniProtKB=A0A1Y1HYJ6	Klebsormidium nitens	LDO