PANTHER Gene Information

Gene Symbol(s):

ezrl

Organism:

Danio rerio

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Gene Name:

Ezrin a

Gene ID:

ZDB-GENE-050522-18

Protein ID:

Q503E6

Persistent Id:

PTN000590070

Alternate Ids:

63102421(GI)	NP_001018326(refSeq)
AAH95359(EMBL-CDS)	ENSDARG00000020944(Ensembl)
Q503E6_DANRE(UniProtKB-ID)	BC165851(EMBL)
ENSDART00000124911(Ensembl_TRS)	Q503E6(Synonym)
ZDB-GENE-050522-18(ZFIN)	ENSDARP00000108896(Ensembl_PRO)
403009(GeneID)
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PANTHER Classification

PANTHER Family:	MERLIN/MOESIN/EZRIN/RADIXIN (PTHR23281)
PANTHER Subfamily:	EZRIN (PTHR23281:SF13)
PANTHER GO-slim Molecular Function:	cell adhesion molecule binding actin binding
PANTHER GO-slim Biological Process:	regulation of vesicle-mediated transport regulation of organelle assembly regulation of cell shape positive regulation of transport positive regulation of protein localization
PANTHER GO-slim Cellular Component:	plasma membrane microvillus apical part of cell adherens junction filopodium
PANTHER protein class:	actin or actin-binding cytoskeletal protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	actin binding, cell adhesion molecule binding, cytoskeletal protein binding
GO BP Complete:	regulation of cell shape, positive regulation of early endosome to late endosome transport, regulation of organelle assembly, developmental process, positive regulation of protein localization to early endosome
GO CC Complete:	microvillus membrane, adherens junction, cytoskeleton, apical part of cell, microvillus, cell cortex, membrane, filopodium, ruffle membrane, plasma membrane, apical plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12691\|UniProtKB=P15311	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000018748.6\|UniProtKB=H2R370	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013301.3\|UniProtKB=G3RBW2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000019457.4\|UniProtKB=H9FZE0	Macaca mulatta	O
MOUSE\|MGI=MGI=98931\|UniProtKB=P26040	Mus musculus	O
RAT\|RGD=621161\|UniProtKB=P31977	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000010347\|UniProtKB=P31976	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000004058.5\|UniProtKB=F1SB42	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000018333.4\|UniProtKB=F7BPT4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000007992.6\|UniProtKB=M3W8S0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845001373.1\|UniProtKB=A0A8I3MKE1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000007642.3\|UniProtKB=A0A5F8GLU3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000001032.3\|UniProtKB=F6QDS8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010005548.1\|UniProtKB=A0A8V0XUZ3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004653.4\|UniProtKB=G1KD48	Anolis carolinensis	O
XENLA\|Gene=ezr.L\|UniProtKB=Q6AX84	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-484766\|UniProtKB=Q5BJ89	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000018142.2\|UniProtKB=H2MV92	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000012128.2\|UniProtKB=H2M9I6	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000016372.1\|UniProtKB=W5NHV7	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000002444.3\|UniProtKB=F6QNQ9	Ciona intestinalis	O
BRAFL\|Gene=LOC118422870\|UniProtKB=A0A9J7LQQ9	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC764541\|UniProtKB=A0A7M7PFI7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00001333\|UniProtKB=G5EBK3	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00033738\|UniProtKB=A8XFS2	Caenorhabditis briggsae	O
DROME\|FlyBase=FBgn0011661\|UniProtKB=P46150	Drosophila melanogaster	O
ANOGA\|Gene_ORFName=AGAP000562\|UniProtKB=Q7PS12	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC000955\|UniProtKB=D6W989	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC016331\|UniProtKB=D7GY91	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC000998\|UniProtKB=D6W9I6	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_327006\|UniProtKB=E9H9F6	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW021858\|UniProtKB=B7Q5K4	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG111783\|UniProtKB=T1EFE5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG185255\|UniProtKB=T1FMK3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG157392\|UniProtKB=T1EMA7	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247943\|UniProtKB=A7SXF9	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG25177\|UniProtKB=B3RY21	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_36461\|UniProtKB=A9UUN2	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_14158\|UniProtKB=A9UPA6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_32815\|UniProtKB=A9V1V5	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_17480\|UniProtKB=A9URX5	Monosiga brevicollis	O