PANTHER Gene Information   
Gene Symbol(s): Them4
Organism: Rattus norvegicus
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Gene Name: Acyl-coenzyme A thioesterase THEM4
Gene ID: 1304723
Protein ID: Q566R0
Persistent Id: PTN000276070
Alternate Ids:
361992(GeneID) ENSRNOP00000028260(Ensembl_PRO)
NP_001020188(refSeq) THEM4_RAT(UniProtKB-ID)
81888054(GI) 3.1.2.2 {ECO:0000250|UniProtKB:Q5T1C6}(EC)
AAH93385(EMBL-CDS) ENSRNOG00000020829(Ensembl)
ENSRNOT00000028260(Ensembl_TRS) BC093385(EMBL)
THEM4(Synonym) Them4(Symbol)
1304723(RGD)
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PANTHER Classification
PANTHER Family: ACYL-COENZYME A THIOESTERASE THEM4 (PTHR12418)
PANTHER Subfamily: ACYL-COENZYME A THIOESTERASE THEM4 (PTHR12418:SF19)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class: esterase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: long-chain fatty acyl-CoA hydrolase activity, hydrolase activity
GO BP Complete: apoptotic process, fatty acid metabolic process, negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, regulation of mitochondrial membrane permeability involved in apoptotic process
GO CC Complete: mitochondrial intermembrane space, mitochondrion, cytosol, ruffle membrane, mitochondrial inner membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: IRS-mediated signalling, VEGFA-VEGFR2 Pathway, Signaling by Insulin receptor, Insulin receptor signalling cascade, PIP3 activates AKT signaling, CD28 dependent PI3K/Akt signaling, Costimulation by the CD28 family, CD28 co-stimulation, IRS-related events triggered by IGF1R, Signaling by VEGF, Signaling by Receptor Tyrosine Kinases, PI3K Cascade, Activation of AKT2, Signal Transduction, Fatty acid metabolism, IGF1R signaling cascade, VEGFR2 mediated vascular permeability, Metabolism, Metabolism of lipids, Negative regulation of the PI3K/AKT network, Immune System, Mitochondrial Fatty Acid Beta-Oxidation, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Intracellular signaling by second messengers, Adaptive Immune System

Orthologs